Mulingo wa Vitamini B12

Mulingo wa vitamini B12 ndimayeso amwazi omwe amayeza kuchuluka kwa vitamini B12 m'magazi anu.

Muyenera kuyesa magazi.

Simuyenera kudya kapena kumwa pafupifupi 6 mpaka 8 maola musanayezedwe.

Mankhwala ena angakhudze zotsatira za kuyesaku. Wothandizira zaumoyo wanu angakuuzeni ngati mukufuna kusiya kumwa mankhwala aliwonse. Musayime mankhwala aliwonse musanalankhule ndi omwe akukuthandizani.

Mankhwala omwe angakhudze zotsatira zake ndi awa:

• Colchicine
• Neomycin
• Para-aminosalicylic acid
• Phenytoin

Pamene singano imayikidwa kuti ikoke magazi, anthu ena amamva kupweteka pang'ono. Ena amangomva kubaya kapena kuluma. Pambuyo pake, pakhoza kukhala kupunduka kapena kuvulala pang'ono. Izi posachedwa zichoka.

Kuyezetsa kumeneku kumachitika nthawi zambiri kukayezetsa magazi kumapereka vuto lotchedwa megaloblastic anemia. Kuchepa kwa magazi koyipa ndi mtundu wa kuchepa kwa magazi m'thupi komwe kumachitika chifukwa cha kuyamwa kwa vitamini B12. Izi zimatha kuchitika m'mimba mukamapanga zinthu zochepa zomwe thupi limafunikira kuyamwa vitamini B12.

Wothandizira anu angalimbikitsenso kuyesa kwa vitamini B12 ngati muli ndi zizindikilo zina zamanjenje. Mulingo wochepa wa B12 ukhoza kuyambitsa dzanzi kapena kumva kulira m'mikono ndi m'miyendo, kufooka, komanso kutayika.

Zina zomwe mayeso angayesedwe ndi monga:

• Chisokonezo chadzidzidzi (delirium)
• Kutaya kwa ntchito yaubongo (dementia)
• Dementia chifukwa cha zomwe zimayambitsa kagayidwe kachakudya
• Zovuta zamitsempha, monga zotumphukira za m'mitsempha

Makhalidwe abwinobwino ndi ma picograms 160 mpaka 950 pa mililita (pg / mL), kapena poto 118 mpaka 701 pa lita (pmol / L).

Mitengo yamtengo wapatali imatha kusiyanasiyana pakati pa ma labotore osiyanasiyana. Ma lab ena amagwiritsa ntchito miyeso yosiyanasiyana kapena amatha kuyesa mitundu yosiyanasiyana. Lankhulani ndi omwe amakupatsani zomwe zotsatira za mayeso anu zikutanthauza.

Makhalidwe ochepera pa 160 pg / mL (118 pmol / L) ndi chizindikiro cha kuchepa kwa vitamini B12. Anthu omwe ali ndi vuto limeneli amatha kukhala kapena kukhala ndi zizindikilo.

Okalamba omwe ali ndi vitamini B12 osakwana 100 pg / mL (74 pmol / L) amathanso kukhala ndi zizindikilo. Kuperewera kuyenera kutsimikiziridwa pofufuza mulingo wa chinthu m'magazi chotchedwa methylmalonic acid. Mulingo wapamwamba umawonetsera kusowa koona kwa B12.

Zomwe zimayambitsa kuchepa kwa vitamini B12 ndizo:

• Mavitamini B12 osakwanira pazakudya (zochepa, kupatula ndi zakudya zamasamba)
• Matenda omwe amayambitsa malabsorption (mwachitsanzo, matenda a leliac ndi matenda a Crohn)
• Kupanda chinthu chofunikira, puloteni yomwe imathandiza m'matumbo kuyamwa vitamini B12
• Pamwambapa kutentha kwapadera (mwachitsanzo, ndi hyperthyroidism)
• Mimba

Mulingo wowonjezera wa vitamini B12 siwachilendo. Kawirikawiri, mavitamini B12 owonjezera amachotsedwa mumkodzo.

Zomwe zitha kukulitsa mulingo wa B12 ndi monga:

• Matenda a chiwindi (monga cirrhosis kapena hepatitis)
• Matenda a Myeloproliferative (mwachitsanzo, polycythemia vera ndi khansa ya m'magazi yayikulu)

Pali chiopsezo chochepa chotenga magazi anu. Mitsempha ndi mitsempha imasiyana mosiyanasiyana kuchokera pa munthu wina kupita kwina komanso kuchokera mbali imodzi ya thupi kupita mbali inayo. Kutenga magazi kuchokera kwa anthu ena kumatha kukhala kovuta kuposa ena.

Zowopsa zina zomwe zimakoka magazi ndi zochepa, koma mwina ndi izi:

• Kutaya magazi kwambiri
• Kukomoka kapena kumva mopepuka
• Ma punctures angapo kuti mupeze mitsempha
• Hematoma (magazi omanga pansi pa khungu)
• Kutenga (chiopsezo chochepa nthawi iliyonse khungu likasweka)

Mayeso a Cobalamin; Kuchepa kwa magazi m'thupi - mulingo wa vitamini B12

Marcogliese AN, Inde DL. Zothandizira a hematologist: ndemanga zomasulira komanso malingaliro osankhidwa a ana akhanda, ana, komanso achikulire. Mu: Hoffman R, Benz EJ, Silberstein LE, et al, olemba. Hematology: Mfundo Zoyambira ndi Zochita. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2018: mutu 162.

Mason JB, Booth SL. Mavitamini, kufufuza mchere, ndi micronutrients ena. Mu: Goldman L, Schafer AI, olemba. Mankhwala a Goldman-Cecil. 26 wa. Philadelphia, PA: Elsevier; 2020: chap 205.