Thandizo la thrombolytic

Thandizo la Thrombolytic ndikugwiritsa ntchito mankhwala osokoneza bongo kuti athyole kapena kupukuta magazi, omwe ndi omwe amayambitsa kwambiri matenda a mtima ndi sitiroko.

Mankhwala a thrombolytic amavomerezedwa kuchipatala ndi matenda amtima mwadzidzidzi. Mankhwala omwe amagwiritsidwa ntchito kwambiri pa thrombolytic therapy ndi minofu ya plasminogen activator (tPA), koma mankhwala ena amatha kuchita zomwezo.

Momwemo, muyenera kulandira mankhwala a thrombolytic mkati mwa mphindi 30 zoyambirira mukafika kuchipatala kuti mukalandire chithandizo.

MTIMA WOKHUDZA

Magazi amateteza mitsempha kumtima. Izi zimatha kuyambitsa matenda amtima, gawo lina la minofu yamtima likafa chifukwa chosowa mpweya womwe umaperekedwa ndi magazi.

Thrombolytics amagwira ntchito pothetsa chovala chachikulu mwachangu. Izi zimathandizira kuyambiranso kwa magazi kulowa mumtima ndikuthandizira kupewa kuwonongeka kwa minofu yamtima. Thrombolytics imatha kuyimitsa matenda amtima omwe angakhale akulu kapena owopsa. Zotsatira zake zimakhala zabwino ngati mulandila mankhwala opatsirana pogonana patatha maola 12 kuchokera pomwe matenda amtima ayamba. Koma mankhwalawa atayamba msanga, zotsatira zake zimakhala zabwino.

Mankhwalawa amabwezeretsa magazi mumtima mwa anthu ambiri. Komabe, kuthamanga kwa magazi kumatha kukhala kosazolowereka ndipo pangakhalebe pang'ono minofu yowonongeka. Mankhwala ena, monga catheterization ya mtima ndi angioplasty ndi kununkhira, angafunike.

Wothandizira zaumoyo wanu azisankhapo zakuti angakupatseni mankhwala a thrombolytic a matenda a mtima pazinthu zambiri. Izi zikuphatikiza mbiri yanu yakumva kupweteka pachifuwa komanso zotsatira za mayeso a ECG.

Zina zomwe zimagwiritsidwa ntchito kuti mudziwe ngati ndinu woyenera bwino wa thrombolytics ndi izi:

• Zaka (achikulire ali pachiwopsezo chowonjezeka cha zovuta)
• Kugonana
• Mbiri yazachipatala (kuphatikiza mbiri yanu yakudwala kwamtima, matenda ashuga, kuthamanga kwa magazi, kapena kugunda kwa mtima)

Nthawi zambiri, thrombolytics sangaperekedwe ngati muli ndi:

• Kuvulala kwamutu kwaposachedwa
• Mavuto okhetsa magazi
• Zilonda zotuluka magazi
• Mimba
• Opaleshoni yaposachedwa
• Kutenga mankhwala ochepetsa magazi monga Coumadin
• Zowopsa
• Kutaya magazi (kuthamanga) kuthamanga kwa magazi

ZOKHUDZA

Zikwapu zambiri zimachitika pamene kuundana kwa magazi kumasunthira mumtsuko wamagazi muubongo ndikuletsa magazi kulowa m'deralo. Kwa zikwapu zotere (stroko ischemic), thrombolytics itha kugwiritsidwa ntchito kuthandizira kufafaniza msanga. Kupereka ma thrombolytics mkati mwa maola atatu azizindikiro zoyamba za stroke kungathandize kuchepetsa kuwonongeka kwa sitiroko ndi kulemala.

Lingaliro loti apatse mankhwalawa lidakhazikitsidwa:

• Kujambula kwa CT kuti muwonetsetse kuti sipadatuluke magazi
• Kuyezetsa thupi komwe kumawonetsa sitiroko yayikulu
• Mbiri yanu yazachipatala

Monga momwe zimakhalira ndi matenda amtima, mankhwala osungunuka oundana samaperekedwa nthawi zambiri ngati muli ndi imodzi mwamavuto omwe atchulidwa pamwambapa.

Thrombolytics samaperekedwa kwa munthu yemwe ali ndi sitiroko yomwe imakhudza kutuluka magazi muubongo. Amatha kukulitsa sitiroko poyambitsa magazi ochulukirapo.

ZOOPSA

Kutaya magazi ndi chiopsezo chofala kwambiri. Zitha kupha moyo.

Kutaya magazi pang'ono kuchokera m'kamwa kapena mphuno kumatha kuchitika pafupifupi 25% ya anthu omwe amalandira mankhwalawa. Kutuluka magazi muubongo kumachitika pafupifupi 1% ya nthawiyo. Kuopsa kumeneku ndi chimodzimodzi kwa odwala sitiroko komanso amtima.

Ngati thrombolytics imawoneka kuti ndi yowopsa, mankhwala ena omwe angayambitse sitiroko kapena matenda amtima ndi awa:

• Kuchotsa khungu (thrombectomy)
• Njira yotsegulira mitsempha yamagazi yochepetsetsa kapena yotseka yomwe imapereka magazi kumtima kapena ubongo

LUMIKIZANANI NDI WOPEREKA WA CHISANGALALO KAPENA KUYITSA 911

Matenda a mtima ndi sitiroko ndizadzidzidzi zamankhwala. Chithandizo chofulumira ndi thrombolytics chimayamba, ndi mwayi wabwino wopezera zabwino.

Matenda a plasminogen activator; TPA; Kutsegula; Kubwereza; Zowonjezera; Yambitsa thrombolytic wothandizila; Othandizira kusungunuka Kuchotsa mankhwala; Sitiroko - thrombolytic; Matenda a mtima - thrombolytic; Embolism pachimake - thrombolytic; Thrombosis - thrombolytic; Lanoteplase; Staphylokinase; Mzere wa Streptokinase (SK); Urokinase; Sitiroko - thrombolytic mankhwala; Matenda a mtima - mankhwala a thrombolytic; Sitiroko - thrombolysis; Matenda a mtima - thrombolysis; M'mnyewa wamtima infarction - thrombolysis

• Sitiroko
• Thrombus
• Kutumiza kwa myocardial infarction ECG wave tracings

Bohula EA, Morrow DA. ST-elevation myocardial infarction: kasamalidwe. Mu: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, olemba. Matenda a Mtima a Braunwald: Buku Lophunzitsira la Mankhwala Amtima. 11th ed. Philadelphia, PA: Elsevier; 2019: mutu 59.

Crocco TJ, Meurer WJ. Sitiroko. Mu: Makoma RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA: Elsevier; 2018: chap 91.

Jaffer IH, Weitz JI. Mankhwala oletsa antithrombotic. Mu: Hoffman R, Benz EJ, Silberstein LE, et al, olemba. Hematology: Mfundo Zoyambira ndi Zochita. Wachisanu ndi chiwiri. Philadelphia, PA: Elsevier; 2018: mutu 149.

O'Gara PT, Kushner FG, Ascheim DD, ndi al. Chitsogozo cha 2013 ACCF / AHA pakuwongolera ST-elevation myocardial infarction: lipoti la American College of Cardiology Foundation / American Heart Association Task Force on Practice Guidelines. Kuzungulira. 2013; 127 (4): 529-555. PMID: 23247303 pubed.ncbi.nlm.nih.gov/23247303/.