Mlembi: Marcus Baldwin
Tsiku La Chilengedwe: 21 Kuni 2021
Sinthani Tsiku: 16 Novembala 2024
Anonim
OPIOID AGONIST-ANTAGONIST | pentazocine | Buprenorphine | partial agonist
Kanema: OPIOID AGONIST-ANTAGONIST | pentazocine | Buprenorphine | partial agonist

Zamkati

Pentazocine imatha kukhala chizolowezi, makamaka pogwiritsa ntchito nthawi yayitali. Tengani pentazocine ndendende monga mwalamulo. Osamutenga wochulukirapo, uzimutenga pafupipafupi, kapena umutenge mosiyana ndi momwe dokotala akuuzira. Pamene mukumwa pentazocine, kambiranani ndi wothandizira zaumoyo wanu zolinga zanu zakuchiritsira, kutalika kwa chithandizo, ndi njira zina zothetsera ululu wanu. Uzani dokotala wanu ngati inu kapena wina aliyense m'banja mwanu amamwa mowa kapena amamwa mowa wambiri, amagwiritsa ntchito mankhwala osokoneza bongo, kapena amamwa mankhwala osokoneza bongo, kapena amamwa mankhwala osokoneza bongo, kapena ngati mwakhala mukudwala kapena matenda ena amisala. Pali chiopsezo chachikulu choti mugwiritse ntchito pentazocine ngati mwakhalapo kapena mwakhalapo ndi izi. Lankhulani ndi omwe amakuthandizani nthawi yomweyo ndikupemphani kuti akuwongolereni ngati mukuganiza kuti muli ndi vuto la opioid kapena pitani ku US Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline ku 1-800-662-HELP.

Pentazocine imatha kubweretsa mavuto opumira kapena owopsa, makamaka munthawi ya 24 mpaka 72 yoyambira yamankhwala anu komanso nthawi iliyonse yomwe mlingo wanu ukuwonjezeka. Dokotala wanu adzakuyang'anirani mosamala mukamalandira chithandizo. Uzani dokotala wanu ngati mwakhala mukucheperapo kapena mphumu. Dokotala wanu angakuuzeni kuti musamwe pentazocine. Uzaninso dokotala wanu ngati mwakhalapo kapena mudakhalapo ndi matenda am'mapapo monga matenda osokoneza bongo (COPD; gulu la matenda omwe amakhudza mapapo ndi njira zapaulendo), kuvulala pamutu, chotupa muubongo, kapena vuto lililonse lomwe limakulitsa kuchuluka kwa kupanikizika mu ubongo wanu. Chiwopsezo choti mutha kukhala ndi vuto lakupuma chimatha kukhala chachikulu ngati ndinu okalamba kapena ofooka kapena osowa zakudya m'thupi chifukwa cha matenda. Ngati mukumane ndi izi, itanani dokotala wanu nthawi yomweyo kapena mupeze chithandizo chamankhwala mwadzidzidzi: kupuma pang'ono, kupuma pang'ono pakati pa kupuma, kapena kupuma pang'ono.


Kumwa mankhwala ena ndi pentazocine kungapangitse kuti mukhale ndi vuto lakupuma, kupuma, kapena kukomoka. Uzani dokotala wanu komanso wamankhwala ngati mukumwa kapena mukufuna kumwa mankhwala aliwonse awa: mankhwala ena ophera fungal kuphatikiza itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), ndi voriconazole (Vfend); benzodiazepines monga alprazolam (Xanax), chlordiazepoxide (Librium), clonazepam (Klonopin), diazepam (Diastat, Valium), estazolam, flurazepam, lorazepam (Ativan), oxazepam, temazepam (Restoril), ndi triazol carbamazepine (Carbatrol, Epitol, Tegretol, Teril); clarithromycin (Biaxin, mu PrevPac); erythromycin (Erytab, Erythrocin); mankhwala ena a kachirombo ka HIV (HIV) kuphatikizapo indinavir (Crixivan), nelfinavir (Viracept), ndi ritonavir (Norvir, ku Kaletra); mankhwala a matenda amisala, nseru, kapena kupweteka; zotsegula minofu; phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rimactane, ku Rifamate); mankhwala ogonetsa; mapiritsi ogona; kapena opondereza. Dokotala wanu angafunike kusintha mlingo wa mankhwala anu ndipo adzakuyang'anirani mosamala. Ngati mutenga pentazocine ndi iliyonse mwa mankhwalawa ndipo mukukhala ndi zizindikiro izi, pitani kuchipatala nthawi yomweyo kapena funani chithandizo chamankhwala mwadzidzidzi: chizungulire chosazolowereka, kupepuka mopepuka, kugona kwambiri, kupuma pang'ono kapena kuvuta, kapena kusayankha. Onetsetsani kuti amene akukusamalirani kapena abale anu akudziwa zomwe zingakhale zovuta kuti athe kuyimbira dokotala kapena chithandizo chamankhwala mwadzidzidzi ngati simungathe kupeza chithandizo chamankhwala panokha.


Kumwa mowa, kumwa mankhwala akuchipatala kapena osapatsirana omwe ali ndi mowa, kapena kugwiritsa ntchito mankhwala osokoneza bongo mukamamwa mankhwala ndi pentazocine kumawonjezera chiopsezo kuti mudzakumana ndi zovuta zoyipa izi. Musamamwe mowa, kumwa mankhwala akuchipatala kapena osalemba omwe muli ndi mowa, kapena kugwiritsa ntchito mankhwala osokoneza bongo mumsewu mukamamwa mankhwala.

Musalole kuti aliyense azimwa mankhwala anu. Pentazocine itha kuvulaza kapena kupha anthu ena omwe amamwa mankhwala anu, makamaka ana.

Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Ngati mumamwa pentazocine pafupipafupi mukakhala ndi pakati, mwana wanu amatha kukhala ndi ziwopsezo zochoka pobereka. Uzani dokotala wa mwana wanu nthawi yomweyo ngati mwana wanu akukumana ndi izi: kukwiya, kusakhazikika, kugona mokwanira, kulira kwambiri, kugwedeza kosalamulirika kwa gawo lina la thupi, kusanza, kutsegula m'mimba, kapena kulephera kunenepa.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Chithandizo cha Mankhwala) mukayamba mankhwala anu ndi pentazocine ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.


Lankhulani ndi dokotala wanu za kuopsa kwa kumwa pentazocine.

Pentazocine imagwiritsidwa ntchito kuthetsa ululu wopweteka kwambiri. Pentazocine ali mgulu la mankhwala otchedwa opiate (narcotic) analgesics. Zimagwira ntchito posintha momwe ubongo ndi dongosolo lamanjenje zimayankhira ndikumva kuwawa.

Pentazocine imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa maola atatu kapena anayi pakufunika. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani pentazocine monga momwe akuuzira.

Mapiritsi a Pentazocine ayenera kumwedwa pakamwa. Musayese kupasuka ndi kubaya mapiritsi. Kubaya jakisoni wa pentazocine kumatha kuyambitsa mavuto akulu azaumoyo kapena kufa. Naloxone imawonjezeredwa pamapiritsi kuti anthu omwe amabaya mapiritsi osungunuka asadzavutike ndi pentazocine.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge pentazocine,

  • uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la pentazocine, naloxone, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a pentazocine. Funsani dokotala wanu kapena wamankhwala mndandanda wa zosakaniza.
  • Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: mankhwala a mutu waching'alang'ala monga almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Alsuma, Imitrex, ku Treximet), ndi zolmitriptan (Zomig); mankhwala a chifuwa, kuzizira, kapena chifuwa; 5HT3 serotonin blockers monga alosetron (Lotronex), dolasetron (Anzemet), granisetron (Kytril), ondansetron (Zofran, Zuplenz), kapena palonosetron (Aloxi); serotonin-reuptake inhibitors monga citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, mu Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Prozac, Pexeva), ndi sertraline (Zoloft); serotonin ndi norepinephrine reuptake inhibitors monga desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), milnacipran (Savella), ndi venlafaxine (Effexor); tramadol; trazodone (Oleptro); ndi tricyclic antidepressants ('mood elevator') monga amitriptyline, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactiline), ndi trimipramine. Komanso uzani dokotala wanu kapena wamankhwala ngati mukumwa kapena kulandira mankhwala aliwonse otsatirawa kapena mwasiya kuwamwa m'masabata awiri apitawa: monoamine oxidase (MAO) inhibitors monga isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), rasagiline (Azilect), selegiline (Emsam, Eldepryl, Zelapar), ndi tranylcypromine (Parnate). Mankhwala ena ambiri amathanso kulumikizana ndi pentazocine, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
  • uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
  • uzani dokotala wanu ngati mwakhala mukukumana ndi mavuto pokodza; kulanda matenda; mapapo, chiwindi, impso, chithokomiro, ndulu, kapena matenda amtima.
  • Uzani dokotala wanu ngati mukuyamwitsa.
  • Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka kwa abambo ndi amai. Lankhulani ndi dokotala wanu za kuopsa kwa kumwa pentazocine.
  • lankhulani ndi dokotala wanu za kugwiritsa ntchito bwino mankhwalawa ngati muli ndi zaka 65 kapena kupitilira apo. Okalamba sayenera kumwa pentazocine chifukwa siotetezeka ngati mankhwala ena omwe angagwiritsidwe ntchito kuthana ndi vuto lomwelo.
  • ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa pentazocine.
  • muyenera kudziwa kuti mankhwalawa akhoza kukupangitsani kugona. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Mankhwalawa nthawi zambiri amatengedwa ngati mukufunikira. Ngati dokotala wakuwuzani kuti muzimwa pentazocine pafupipafupi, tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Pentazocine ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • kumva kutopa kwambiri
  • wamisala
  • Kusinza
  • zosintha
  • mutu
  • kukhumudwa m'mimba
  • kudzimbidwa
  • kupweteka m'mimba
  • zidzolo
  • kuvuta kukodza

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo:

  • kuvuta kupuma
  • kusintha kwa kugunda kwa mtima
  • kusakhazikika, kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe), malungo, thukuta, chisokonezo, kugunda kwamtima, kunjenjemera, kuuma minofu mwamphamvu kapena kugwedezeka, kutayika kwa mgwirizano, nseru, kusanza, kapena kutsekula m'mimba
  • nseru, kusanza, kusowa kwa njala, kufooka, kapena chizungulire
  • Kulephera kupeza kapena kusunga erection
  • msambo wosasamba
  • Kuchepetsa chilakolako chogonana
  • kukomoka

Pentazocine ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Mukamamwa pentazocine, muyenera kukambirana ndi adotolo za mankhwala opulumutsa omwe amatchedwa naloxone omwe amapezeka mosavuta (mwachitsanzo, kunyumba, ofesi). Naloxone imagwiritsidwa ntchito kusintha zomwe zimawopseza moyo chifukwa cha bongo. Zimagwira ntchito poletsa zotsatira za ma opiate kuti athetse zovuta zomwe zimayambitsidwa ndi ma opiate ambiri m'magazi. Dokotala wanu amathanso kukupatsirani naloxone ngati mukukhala m'nyumba momwe muli ana aang'ono kapena wina yemwe wagwiritsa ntchito mankhwala osokoneza bongo mumsewu. Muyenera kuwonetsetsa kuti inu ndi abale anu, osamalira odwala, kapena anthu omwe mumacheza nanu mukudziwa momwe mungadziwire kuchuluka kwa mankhwala osokoneza bongo, momwe mungagwiritsire ntchito naloxone, ndi zomwe muyenera kuchita mpaka chithandizo chadzidzidzi chidzafike. Dokotala wanu kapena wamankhwala akuwonetsani inu ndi abale anu momwe mungagwiritsire ntchito mankhwalawa. Funsani wamankhwala wanu kuti akupatseni malangizowo kapena pitani patsamba la wopanga kuti mupeze malangizowo. Ngati zizindikilo za bongo zikachitika, mnzanu kapena wachibale akuyenera kupereka mlingo woyamba wa naloxone, itanani 911 mwachangu, ndikukhala nanu ndikukuyang'anirani mpaka thandizo ladzidzidzi litafika. Zizindikiro zanu zimatha kubwerera mkati mwa mphindi zochepa mutalandira naloxone. Ngati zizindikiro zanu zibwerera, munthuyo akuyenera kukupatsaninso mankhwala a naloxone. Mlingo wowonjezerapo ungaperekedwe mphindi ziwiri kapena zitatu zilizonse, ngati zizindikiro zibwerera chithandizo chamankhwala chisanabwere.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

  • kupuma pang'ono kapena pang'ono
  • kuvuta kupuma
  • kugona kwambiri
  • osakhoza kuyankha kapena kudzuka

Sungani maimidwe onse ndi dokotala ndi labotale. Dokotala wanu akhoza kuyitanitsa mayeso ena a labu kuti muwone momwe thupi lanu lingayankhire pentazocine.

Musanayesedwe mu labotale (makamaka yomwe imakhudza methylene buluu), uzani adotolo anu ndi ogwira nawo ntchito kuti mukumwa pentazocine.

Musalole kuti aliyense azimwa mankhwala anu. Pentazocine ndi chinthu cholamulidwa. Malangizo amatha kudzazidwanso kangapo; funsani wamankhwala wanu ngati muli ndi mafunso.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Talwin® NX
  • Talacen® (monga chinthu chophatikizira chomwe chili ndi Acetaminophen, Pentazocine)

Chogulitsa ichi sichikupezeka pamsika. Njira zina zitha kupezeka.

Idasinthidwa Komaliza - 02/15/2021

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