Ezetimibe

Zamkati

• Musanatenge ezetimibe,
• Ezetimibe atha kubweretsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Zizindikiro zotsatirazi sizachilendo, koma ngati mungakumane ndi zina mwazi, itanani dokotala wanu mwachangu:

Ezetimibe imagwiritsidwa ntchito limodzi ndi kusintha kwa moyo (zakudya, kuchepa thupi, kuchita masewera olimbitsa thupi) kuti muchepetse kuchuluka kwa cholesterol (chinthu chonga mafuta) ndi mafuta ena m'magazi. Itha kugwiritsidwa ntchito yokha kapena kuphatikiza ndi HMG-CoA reductase inhibitor (statin). Ezetimibe ali mgulu la mankhwala otchedwa mankhwala ochepetsa mafuta m'thupi. Zimagwira ntchito poletsa kuyamwa kwa cholesterol m'matumbo.

Kuchulukana kwa cholesterol ndi mafuta pamakoma amitsempha yamagazi (njira yotchedwa atherosclerosis) kumachepetsa kuthamanga kwa magazi, komwe kumachepetsa kuperekera kwa oxygen pamtima, ubongo, ndi ziwalo zina za thupi. Kuchepetsa magazi m'magazi a cholesterol ndi mafuta kumatha kuchepetsa kuchepa kwamtunduwu ndipo kumachepetsa mwayi wanu wokhala ndi vuto la mtima monga angina (kupweteka pachifuwa), zilonda, ndi matenda amtima. Zotsatira za kafukufuku wamankhwala omwe amafanizira anthu omwe adatenga ezetimibe ndi simvastatin ndi anthu omwe adatenga simvastatin okha adapeza kuti ngakhale gulu la anthu omwe amatenga ezetimibe ndi simvastatin anali ndi cholesterol m'mwazi, panalibe kusiyana pakati pamagulu awiriwo mu kuchuluka wa mafuta m'thupi ndi mafuta omanga mkatikati mwa mitsempha m'khosi. Sizimamveka pakadali pano chifukwa chomwe kutsika kwa mafuta m'magazi sikunapangitse kuchepa kwama cholesterol ndi mafuta ambiri pamakoma amitsempha yamagazi mwa anthu omwe amatenga ezetimibe ndi simvastatin. Maphunziro ena akuchitika poyerekeza chithandizo ndi ezetimibe ndi simvastatin kuchipatala ndi simvastatin yekha kuti awone ngati pali kusiyana pachiwopsezo chodwala matenda amtima. Lankhulani ndi dokotala wanu ngati muli ndi mafunso okhudzana ndi kuopsa ndi phindu lakuwonjezera kuchuluka kwa mafuta m'magazi anu ndi ezetimibe ndi mankhwala ena.

Kuphatikiza pa kumwa mankhwala ochepetsa mafuta m'thupi, kusintha zina ndi zina m'machitidwe anu atsiku ndi tsiku kumathandizanso kuchepa kwama cholesterol. Muyenera kudya zakudya zopanda mafuta ambiri ndi mafuta (onani SPECIAL DIETARY); yesetsani mphindi 30, mwina osakhala onse, masiku; ndi kuonda ngati onenepa kwambiri.

Ezetimibe amabwera ngati piritsi kuti atenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku kapena wopanda chakudya. Kukuthandizani kukumbukira kukumbukira kutenga ezetimibe, tengani nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani ezetimibe ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Pitilizani kutenga ezetimibe ngakhale mukumva bwino. Osasiya kumwa ezetimibe osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge ezetimibe,

• uzani dokotala wanu komanso wamankhwala ngati mukugwirizana ndi ezetimibe kapena mankhwala aliwonse.
• auzeni dokotala ndi wazamankhwala mankhwala omwe akupatsani, osavomerezeka, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa. Onetsetsani kuti mwatchulapo izi: anticoagulants ('' opopera magazi '') monga warfarin (Coumadin); cyclosporine (Neoral, Sandimmune); fenofibrate (TriCor); ndi gemfibrozil (Lopid). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• ngati mukumwa cholestyramine (Questran), colesevelam (WellChol), kapena colestipol (Colestid), tengani maola 4 musanadutse kapena maola awiri kuchokera ezetimibe.
• uzani dokotala wanu ngati mwakhalapo kapena mudakhalapo ndi matenda a chiwindi.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga ezetimibe, itanani dokotala wanu.

Idyani chakudya chochepa cha mafuta, cholesterol. Onetsetsani kuti mukutsatira zolimbitsa thupi komanso malingaliro azakudya zomwe adokotala anu kapena odyetsa. Mutha kuchezanso tsamba la National Cholesterol Education Program (NCEP) kuti mumve zambiri za zakudya pa http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Ezetimibe atha kubweretsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• mutu
• chizungulire
• kutsegula m'mimba
• chikhure
• mphuno
• kuyetsemula
• kupweteka pamodzi

Zotsatira zina zoyipa zingakhale zazikulu. Zizindikiro zotsatirazi sizachilendo, koma ngati mungakumane ndi zina mwazi, itanani dokotala wanu mwachangu:

• ming'oma
• zidzolo
• kuyabwa
• kuvuta kupuma kapena kumeza
• kutupa kwa nkhope, mmero, lilime, milomo, maso, manja, mapazi, akakolo, kapena miyendo yakumunsi
• ukali
• kukhumudwa m'mimba
• kutopa kwambiri
• kutuluka mwachilendo kapena kuphwanya
• kusowa mphamvu
• kusowa chilakolako
• kupweteka kumtunda chakumanja kwam'mimba
• chikasu cha khungu kapena maso
• zizindikiro ngati chimfine
• kupweteka kwa minofu kapena kufooka
• malungo
• kuzizira
• ndowe zotumbululuka kapena zonenepa
• kupweteka pachifuwa

Ezetimibe atha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu adzaitanitsa mayeso ena a labu asanadye komanso mukamalandira chithandizo kuti muwone momwe thupi lanu likuyankhira ku ezetimibe.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Zetia^®

• Liptruzet^® (okhala ndi Atorvastatin, Ezetimibe)
• Nexlizet^® (okhala ndi Bempedoic Acid, Ezetimibe)
• Vytorin^® (munali Ezetimibe, Simvastatin)