Atazanavir

Zamkati

• Musanatenge atazanavir,
• Atazanavir amatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:
• Ngati mwayamba kuthamanga kwambiri ndi zizindikiro izi, lekani kumwa atazanavir ndipo itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi:
• Zizindikiro za bongo zingaphatikizepo izi:

Atazanavir imagwiritsidwa ntchito limodzi ndi mankhwala ena, monga ritonavir (Norvir), kuchiza matenda opatsirana pogonana a HIV mwa achikulire ndi ana omwe ali ndi miyezi yosachepera itatu ndipo amalemera pafupifupi 22 lb (10 kg). Atazanavir ali mgulu la mankhwala otchedwa protease inhibitors. Zimagwira ntchito pochepetsa kuchuluka kwa kachilombo ka HIV m'magazi. Ngakhale atazanavir sachiza kachilombo ka HIV, imatha kuchepetsa mwayi wanu wopeza matenda a immunodeficiency syndrome (AIDS) ndi matenda okhudzana ndi HIV monga matenda akulu kapena khansa. Kumwa mankhwalawa limodzi ndi kuchita zogonana motetezeka ndikusintha zina ndi zina pamoyo kungachepetse chiopsezo chotenga kachirombo ka HIV kwa anthu ena.

Atazanavir imabwera ngati kapisozi komanso ngati ufa woti utenge pakamwa. The kapisozi ndi ufa nthawi zambiri amatengedwa kamodzi patsiku ndi chakudya kapena chotupitsa. Tengani atazanavir mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani atazanavir ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Mumwa mankhwala ena a HIV mukamamwa atazanavir. Dokotala wanu angakuuzeni ngati mankhwalawa ayenera kumwa nthawi imodzimodzi ndi atazanavir, kapena maola angapo musanatenge atazanavir. Tsatirani ndondomekoyi mosamala, ndipo funsani dokotala wanu kapena wamankhwala ngati muli ndi mafunso okhudza nthawi yomwe muyenera kumwa mankhwala anu.

Atazanavir ufa ayenera kutengedwa ndi ritonavir (Norvir). Musatenge atazanavir ufa wopanda ritonavir (Norvir).

Kumeza makapisozi lonse; osagawana, kutafuna, kapena kutsegula. Ngati mukulephera kumeza makapisozi, uzani dokotala kapena wamankhwala.

Mafuta a Atazanavir atha kuwonjezeredwa ku zakudya monga maapulosi kapena yogurt, kapena zakumwa monga madzi, mkaka, kapena mkaka wa makanda. Sakanizani bwino, ndipo tengani chisakanizo chonse nthawi yomweyo kuti mutenge mokwanira. Mukasakaniza ndi madzi, idyani chotupitsa kapena chakudya nthawi yomweyo mutatha kusakaniza ufa. Kwa makanda (opitilira miyezi itatu zakubadwa) osakhoza kumwa kuchokera mu chikho, ufa ungasakanikidwe ndi chilinganizo cha makanda ndi kuperekedwa ndi jakisoni wamkamwa; osapereka chisakanizo kwa khanda mu botolo la mwana. Ngati osakaniza satengedwa nthawi yomweyo amayenera kusungidwa kutentha ndikutenga ola limodzi. Werengani mosamala malangizo a opanga omwe amafotokoza momwe mungasakanizire ndi kumwa mlingo wa atazanavir. Onetsetsani kuti mufunse wamankhwala kapena dokotala wanu ngati muli ndi mafunso okhudza momwe mungasakanizire kapena kumwa mankhwalawa.

Lankhulani ndi dokotala zomwe muyenera kuchita ngati mwana wanu akusanza, kulavulira, kapena kutenga gawo limodzi la mlingo wa atazanavir.

Atazanavir imathandizira kupewa kachilombo ka HIV, koma sikumachiritsa. Pitirizani kutenga atazanavir ngakhale mutakhala bwino. Osasiya kumwa atazanavir osalankhula ndi dokotala. Katundu wanu wa atazanavir ukayamba kuchepa, pezani zambiri kuchokera kwa dokotala kapena wamankhwala. Mukasiya kumwa atazanavir kapena kudumpha mlingo, matenda anu akhoza kukhala ovuta kuchiza.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso.

Atazanavir imagwiritsidwanso ntchito popewera matenda kwa ogwira ntchito zaumoyo kapena anthu ena omwe adapezeka ndi HIV mwangozi. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa ngati muli ndi vuto lanu.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge atazanavir,

• uzani dokotala ndi wamankhwala ngati muli ndi vuto la atazanavir, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu makapisozi a atazanavir kapena ufa. Dokotala wanu akhoza kukuwuzani kuti musatenge atazanavir. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala ngati mukumwa mankhwala aliwonse otsatirawa kapena mankhwala azitsamba: alfuzosin (Uroxatral); cisapride (Propulsid; sikupezeka ku US); elbasvir ndi grazoprevir (Zepatier); ergot alkaloids monga dihydroergotamine (DHE 45, Migranal), ergonovine, ergotamine (Ergomar, ku Cafergot, ku Migergot), kapena methylergonovine (Methergine); glecaprevir ndi pibrentasvir (Mavyret); indinavir (Crixivan); irinotecan (Camptosar); lovastatin (Altoprev); lurasidone (Latuda); midazolam pakamwa; nevirapine (Viramune), pimozide (Orap); rifampin (Rimactane, Rifadin, ku Rifater, ku Rifamate); sildenafil (mtundu wa Revatio wokha womwe umagwiritsidwa ntchito matenda am'mapapo); simvastatin (Zocor, ku Vytorin); Chingwe cha St. ndi triazolam (Halcion). Dokotala wanu angakuwuzeni kuti musamwe atazanavir ngati mukumwa mankhwala amodzi kapena angapo.
• Uzani dokotala wanu komanso wamankhwala mankhwala ena omwe simukupatsidwa, mavitamini, mankhwala azitsamba, ndi zowonjezera zakudya zomwe mumamwa kapena mukukonzekera.Onetsetsani kuti mwatchulapo izi: maanticoagulants ('opopera magazi') monga warfarin (Coumadin, Jantoven); antidepressants ('mood elevators') monga amitriptyline, desipramine (Norpramin), doxepin (Silenor, Zonalon), imipramine (Tofranil, Surmontil), protriptyline (Vivactil), trazodone, ndi trimipramine (Surmontil); ma antifungals ena monga itraconazole (Onmel, Sporanox), ketoconazole (Extina, Nizoral, Xolegel), ndi voriconazole (Vfend); bepridil (Vascor) (sakupezeka ku US); zotchinga beta monga labetalol (Trandate), nadolol (Corgard, ku Corzide), ndi propranolol (Hemangeol, Inderal, Innopran XL, ku Inderide); boceprevir (sakupezekanso ku US; Victrelis); chifuwa (Tracleer); buprenorphine (Buprenex, Butrans, ku Bunavail, ku Suboxone, ku Zubsolv); calcium blockers monga diltiazem (Cardizem, Cartia, Tiazac, ena), felodipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab, Procardia), ndi verapamil (Calan, Verelan, ku Tarka, ena); mankhwala ochepetsa mafuta m'thupi (ma statins) monga atorvastatin (Lipitor, ku Caduet), ndi rosuvastatin (Crestor); clarithromycin (Biaxin, mu Prevpac); colchicine (Colcrys, Mitigare); digoxin (Lanoxin); fluticasone (Flonase, Flovent, ku Advair); mankhwala a kugunda kwamtima mosasinthasintha monga amiodarone (Cordarone, Nexterone, Pacerone), lidocaine (Octocaine, Xylocaine), ndi quinidine (ku Nuedexta); mankhwala omwe amaletsa chitetezo cha mthupi monga cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), ndi tacrolimus (Astagraf, Prograf); mankhwala ena a HIV kapena Edzi kuphatikiza efavirenz (Sustiva, ku Atripla), ritonavir (Norvir, ku Kaletra, ku Viekira Pak), saquinavir (Invirase), ndi tenofovir (Viread, ku Atripla, ku Stribild, ku Truvada, ena); midazolam ndi jakisoni; paclitaxel (Abraxane, Taxol); ena a phosphodiesterase inhibitors (PDE-5 inhibitors) omwe amagwiritsidwa ntchito pa erectile dysfunction monga sildenafil (Viagra), tadalafil (Cialis), ndi vardenafil (Levitra, Staxyn); repaglinide (Prandin, ku Prandimet); quetiapine (Seroquel); rifabutin (Mycobutin); salmeterol (Serevent, ku Advair); sofosbuvir, velpatasvir, ndi voxilaprevir (Sovaldi, Epclusa, Vosevi); ndi tadalafil (Adcirca, Cialis). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi atazanavir, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• ngati mukumwa maantacids, didanosine ochedwa-release capsule (Videx EC), kapena mankhwala ena aliwonse otetezedwa monga buffered aspirin (Bufferin), imwani atazanavir maola 2 isanakwane kapena ola limodzi mutamwa mankhwala. Funsani dokotala wanu kapena wamankhwala ngati simukudziwa ngati mankhwala omwe mukumwa akuwongolera.
• Uzani dokotala wanu ngati mukumwa mankhwala a kudzimbidwa, kutentha pa chifuwa, kapena zilonda monga cimetidine, esomeprazole (Nexium, ku Vimovo), famotidine (Pepcid, ku Duexis), lansoprazole (Prevacid, Prevpac), nizatidine (Axid), omeprazole (Prilosec, mu Zegerid), pantoprazole (Protonix), rabeprazole (AcipHex), kapena ranitidine (Zantac). Dokotala wanu angakuuzeni kuti musamwe mankhwala kapena kumwa mankhwala ochepa. Ngati mupitiliza kumwa mankhwalawa, adokotala angakuuzeni nthawi yochuluka bwanji yomwe muyenera kulandira pakati pa kumwa mankhwalawa ndi kumwa atazanavir.
• auzeni adotolo ngati mwakhala mukugunda pamtima mosasinthasintha, matenda ashuga kapena shuga wambiri m'magazi, hemophilia (matenda omwe magazi samatseka mwachizolowezi) kapena matenda ena aliwonse otuluka magazi, hepatitis (matenda opatsirana a chiwindi) kapena Matenda ena a chiwindi, impso kapena matenda amtima.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Mukakhala ndi pakati mukatenga atazanavir, itanani dokotala wanu. Simuyenera kuyamwitsa ngati muli ndi kachilombo ka HIV ndipo mukumwa atazanavir.
• Muyenera kudziwa kuti atazanavir imachepetsa mphamvu yolera yakumapiritsi (mapiritsi oletsa kubala, zigamba, mphete, zopangira, ndi jakisoni). Lankhulani ndi dokotala wanu za njira zakulera zomwe zingakuthandizeni mukamamwa atazanavir.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani adotolo kapena dokotala kuti mukumwa atazanavir.
• muyenera kudziwa kuti mutha kukhala ndi hyperglycemia (kuchuluka kwa shuga m'magazi anu) mukamamwa mankhwalawa, ngakhale mulibe matenda ashuga. Uzani dokotala wanu nthawi yomweyo ngati muli ndi zizindikiro izi mukamamwa atazanavir: ludzu lokwanira, kukodza pafupipafupi, njala yayikulu, kusawona bwino, kapena kufooka. Ndikofunika kuyimbira dokotala wanu mukangomva izi, chifukwa shuga wambiri yemwe samalandira mankhwala amatha kuyambitsa vuto lalikulu lotchedwa ketoacidosis. Ketoacidosis imatha kukhala pangozi ngati singachiritsidwe koyambirira. Zizindikiro za ketoacidosis zimaphatikizapo: pakamwa pouma, nseru ndi kusanza, kupuma movutikira, mpweya womwe umanunkhira zipatso, ndikuchepetsa chidziwitso.
• muyenera kudziwa kuti pamene mukumwa atazanavir mafuta anu amthupi amatha kuchuluka kapena kusunthira mbali zosiyanasiyana za thupi lanu monga kumbuyo kwa khosi lanu ndi mapewa apamwamba ('njati hump'), m'mimba, ndi mabere. Mutha kutaya mafuta m'manja, miyendo, nkhope, ndi matako. Lankhulani ndi dokotala ngati muwona kusintha kulikonse kwamafuta anu.
• ngati muli ndi phenylketonuria (PKU, mkhalidwe wobadwa nawo momwe muyenera kudya chakudya chapadera kuti muchepetse kuchepa kwamaganizidwe), muyenera kudziwa kuti atazanavir ufa wothira umakomedwa ndi aspartame yomwe imapanga phenylalanine.
• muyenera kudziwa kuti pamene mukumwa mankhwala ochizira kachilombo ka HIV, chitetezo chanu cha mthupi chingakhale champhamvu ndikuyamba kulimbana ndi matenda ena omwe anali kale mthupi lanu. Izi zitha kukupangitsani kukhala ndi zizindikilo za matendawa. Ngati muli ndi zizindikilo zatsopano kapena zowonjezeka nthawi iliyonse mukamachiza ndi atazanavir, onetsetsani kuti mwauza dokotala.

Lankhulani ndi dokotala wanu za kudya zipatso zamtengo wapatali kapena kumwa madzi amphesa mukamamwa mankhwalawa.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Atazanavir amatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kupweteka m'mimba
• kutsegula m'mimba
• mutu
• kukhumudwa
• malungo
• kuvuta kugona kapena kugona
• kupweteka kwa minofu
• zidzolo pang'ono
• dzanzi, kutentha, kupweteka, kapena kulira kwa manja kapena mapazi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• kugunda kwamtima kosasintha
• chizungulire
• kumverera kukomoka kapena kupepuka mutu
• masomphenya amasintha
• chikasu cha khungu kapena maso (makamaka makanda akhanda)
• kupweteka kumbuyo kwanu kapena mbali
• kupweteka kapena kutentha ndi kukodza
• magazi mkodzo
• kusanza
• kusowa chilakolako
• kutupa kwa manja, mapazi, miyendo, kapena akakolo
• kuchepa pokodza
• mkodzo wamtundu wakuda
• matumbo ofiira owala
• erection yomwe imatenga nthawi yayitali kuposa maola 4

Ngati mwayamba kuthamanga kwambiri ndi zizindikiro izi, lekani kumwa atazanavir ndipo itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi:

• kudwaladwala kapena 'chimfine' zizindikiro
• malungo
• minofu kapena molumikizana mafupa
• ofiira kapena otupa maso
• matuza kapena khungu losenda
• zilonda mkamwa
• kutupa kwa nkhope kapena khosi lanu
• zopweteka, zotentha, kapena zofiira pansi pa khungu lanu

Atazanavir imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe kapena paketi yomwe idabwera, yotsekedwa mwamphamvu, ndipo ana ndi ziweto sangathe kuzipeza. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• chikasu kapena khungu

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu musanachitike komanso mukamalandira chithandizo kuti muwone momwe thupi lanu likuyankhira ku atazanavir.

Sungani atazanavir pafupi. Musayembekezere mpaka mutatsala pang'ono kumwa mankhwala kuti mudzaze mankhwala anu.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Reyataz^®

• Evotaz^® (yokhala ndi Atazanavir, Cobicistat)

• ATZ