Lapatinib

Zamkati

• Musanatenge lapatinib,
• Lapatinib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHACHENJEZO kapena gawo LOPHUNZITSIRA, itanani dokotala wanu mwachangu:
• Zizindikiro za bongo zingaphatikizepo izi:

Lapatinib ikhoza kuwononga chiwindi chomwe chitha kukhala chowopsa kapena chowopseza moyo. Kuwonongeka kwa chiwindi kumatha kuchitika patangotha ​​masiku angapo kapena miyezi ingapo kuchokera pomwe mankhwala amayamba ndi lapatinib. Uzani dokotala wanu ngati mwakhalapo kapena mukudwala matenda a chiwindi. Ngati mukumane ndi izi, itanani dokotala wanu nthawi yomweyo: kuyabwa, chikasu pakhungu kapena maso, mkodzo wamdima, kupweteka kumtunda kwakumimba kwam'mimba, kutuluka mwazi kapena mikwingwirima yachilendo, kapena mipando yotumbululuka kapena yakuda.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labotale musanachitike komanso mukamalandira chithandizo kuti muwone ngati chiwindi chanu chitha kuwonongeka kapena chawonongeka ndi lapatinib.

Lankhulani ndi dokotala wanu za kuopsa kotenga lapatinib.

Lapatinib imagwiritsidwa ntchito ndi capecitabine (Xeloda) kuti ithetse mtundu wina wa khansa ya m'mawere mwa anthu omwe adalandira kale mankhwala ena a chemotherapy. Lapatinib imagwiritsidwanso ntchito ndi letrozole (Femara) kuchiza mtundu wina wa khansa ya m'mawere mwa amayi omwe atha msambo (azimayi omwe asintha moyo, kumapeto kwa msambo) omwe afalikira mbali zina za thupi. Lapatinib ali mgulu la mankhwala otchedwa kinase inhibitors. Zimagwira ntchito poletsa mapuloteni achilendo omwe amawonetsa kuti ma cell a khansa achulukane. Izi zimathandiza kuletsa kapena kuchepetsa kufalikira kwa maselo a khansa.

Lapatinib imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku, osachepera ola limodzi isanakwane kapena ola limodzi mutadya. Lapatinib imagwiritsidwa ntchito pochiza khansa ya m'mawere kapena yamatenda, imaperekedwa kamodzi tsiku lililonse pa masiku 1 mpaka 21 (limodzi ndi capecitabine masiku a 1 mpaka 14) a masiku 21. Kuzungulira kumatha kubwerezedwa monga momwe dokotala akuwalimbikitsira. Lapatinib imagwiritsidwa ntchito pochiza khansa ya m'mawere mwa amayi omwe atha msinkhu, amatha kupatsidwa kamodzi tsiku lililonse pamodzi ndi letrozole. Tengani mapiritsi onse a lapatinib anu tsiku lililonse nthawi imodzi; osagawaniza mapiritsi kuti atenge ngati mlingo umodzi. Tengani lapatinib mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani lapatinib ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi lonse; osagawana, kutafuna, kapena kuwaphwanya.

Dokotala wanu akhoza kuwonjezera pang'onopang'ono kapena kuchepetsa mlingo wa lapatinib mukamamwa mankhwala. Izi zimadalira momwe mankhwalawa amakuthandizirani komanso zovuta zina zomwe mungakumane nazo. Pitirizani kutenga lapatinib ngakhale mutakhala bwino. Osasiya kumwa lapatinib osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge lapatinib,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la lapatinib, mankhwala ena aliwonse, kapena chilichonse mwapiritsi a lapatinib. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala omwe simukulembera, mavitamini, ndi zowonjezera zakudya zomwe mumamwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: maantibayotiki ena monga clarithromycin (Biaxin, mu Prevpac), erythromycin (EES, E-Mycin, Erythrocin), moxifloxacin (Avelox), rifabutin (Mycobutin), rifampin (Rifadin, in Rifamate, in Rifater, Rimactane), rifapentine (Priftin), sparfloxacin (Zagam) (sakupezeka ku US), ndi telithromycin (Ketek); antifungals monga itraconazole (Sporanox), ketoconazole (Nizoral), ndi voriconazole (Vfend); calcium blockers monga amlodipine (Norvasc, ku Caduet ndi Lotrel), diltiazem (Cardizem, Dilacor, Tiazac, ena), felodipine (Plendil, ku Lexxel), nifedipine (Adalat, Nifedical XL, Procardia, ena), nisoldipine (Sular) , ndi verapamil (Calan, Isoptin, Verelan, ena); cisapride (Propulsid) (sikupezeka ku U.S.); dexamethasone (Decadron, Dexpak); mankhwala ena okhumudwa monga nefazodone; mankhwala ena a chemotherapy kuphatikiza daunorubicin (Cerubidine, DaunoXome), doxorubicin (Adriamycin, Doxil, Rubex), epirubicin (Ellence), idarubicin (Idamycin), tamoxifen (Nolvadex), valrubicin (Valstar), vinblastine, vinblastine, mankhwala ena opatsirana pogonana (HIV) kapena matenda opatsirana m'thupi (AIDS) kuphatikiza atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, ku Kaletra), ndi saquinavir (Invirase); mankhwala osagunda pamtima kuphatikiza amiodarone (Cordarone), disopyramide (Norpace), dofetilide (Tikosyn), procainamide (Procanbid), quinidine, ndi sotalol (Betapace, Betapace AF, Sorine); mankhwala ena ogwidwa monga carbamazepine (Carbatrol, Epitol, Tegretol), phenobarbital (Luminal), ndi phenytoin (Dilantin, Phenytek); pimozide (Orap); ndi thioridazine. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi lapatinib, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu komanso wazamankhwala zomwe mumamwa mankhwala azitsamba, makamaka wort ya St.
• auzeni adotolo ngati mwakhala mukugunda pang'onopang'ono, mwachangu, kapena mosasinthasintha; nthawi yayitali ya QT (vuto losowa la mtima lomwe lingayambitse kugunda kwamtima, kukomoka, kapena kufa mwadzidzidzi); mlingo wotsika wa magnesium kapena potaziyamu m'magazi anu; kapena matenda amtima kapena am'mapapo.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Muyenera kuyezetsa mimba musanayambe mankhwala. Ngati ndinu mayi amene amatha kutenga pakati, muyenera kugwiritsa ntchito njira yoletsa yothandiza kubereka mukamalandira chithandizo komanso kwa sabata limodzi mutapatsidwa mankhwala omaliza. Ngati ndinu wamwamuna wokhala ndi mkazi yemwe angatenge mimba, muyenera kugwiritsa ntchito njira yolerera yoyenerera mukamalandira chithandizo komanso kwa sabata limodzi mutapatsidwa mankhwala omaliza. Lankhulani ndi dokotala wanu za njira zolerera zomwe mungagwiritse ntchito mukamachiza. Mukakhala ndi pakati mukatenga lapatinib, itanani dokotala wanu mwachangu. Lapatinib ikhoza kuvulaza mwana wosabadwayo.
• auzeni dokotala ngati mukuyamwitsa kapena mukufuna kuyamwitsa. Simuyenera kuyamwa mukamamwa lapatinib komanso kwa sabata limodzi mutapatsidwa mankhwala omaliza.
• muyenera kudziwa kuti lapatinib nthawi zambiri imayambitsa kutsegula m'mimba, komwe kumatha kukhala koopsa. Itanani dokotala wanu ngati muli ndi matenda otsekula m'mimba mukamatenga lapatinib. Dokotala wanu angakuuzeni kuti muzimwa zakumwa zambiri, musinthe zakudya zanu, komanso mutenge mankhwala kuti muchepetse kutsekula m'mimba ndikupewa kutaya madzi m'thupi (kutaya madzi ochulukirapo m'thupi lanu). Itanani dokotala wanu nthawi yomweyo ngati mukukumana ndi zizindikiro zotsatirazi za kuchepa kwa madzi m'thupi: ludzu lalikulu, mkamwa wouma komanso / kapena khungu, kuchepa kwamadzi, maso otayika, kapena kugunda kwamtima.

Musadye zipatso zamphesa kapena kumwa madzi amphesa mukamamwa mankhwalawa.

Tengani mlingo womwe mwaphonya mukangokumbukira tsiku lomwelo. Komabe, ngati simukumbukira mpaka tsiku lotsatira, ngati simukumbukira ngati munamwa mankhwalawo, kapena ngati musanza mankhwala anu, dumpha mlingo womwe mwaphonyawo ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Lapatinib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kutentha pa chifuwa
• zilonda pamilomo, mkamwa, kapena pakhosi
• kusowa chilakolako
• zofiira, zopweteka, dzanzi, kapena kumenyetsa manja ndi mapazi
• khungu lowuma
• kupweteka m'manja, miyendo, kapena kumbuyo
• kuvuta kugona kapena kugona

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHACHENJEZO kapena gawo LOPHUNZITSIRA, itanani dokotala wanu mwachangu:

• kupuma movutikira
• chifuwa chowuma
• kukhosomola ntchofu zapinki kapena zamagazi
• kuthamanga, kusasinthasintha, kapena kugunda kwamtima
• kufooka
• kutupa kwa manja, mapazi, akakolo, kapena miyendo yakumunsi
• zidzolo
• malungo
• khungu kapena khungu

Lapatinib ingasinthe momwe mtima wanu umagundira ndikupopera magazi kudzera mthupi lanu. Dokotala wanu adzakuyang'anirani mosamala kuti awone ngati lapatinib yakhudza mtima wanu. Lankhulani ndi dokotala wanu za kuopsa kotenga lapatinib.

Lapatinib ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kutsegula m'mimba
• kusanza

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Zamgululi^®