Raltegravir

Zamkati

• Musanatenge raltegravir,
• Raltegravir ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

Raltegravir imagwiritsidwa ntchito limodzi ndi mankhwala ena kuchiza matenda opatsirana kudzera m'thupi (HIV) mwa akulu ndi ana omwe amalemera makilogalamu awiri ndi theka. Raltegravir ali mgulu la mankhwala otchedwa HIV integrase inhibitors. Zimagwira ntchito pochepetsa kuchuluka kwa kachilombo ka HIV m'magazi. Ngakhale raltegravir sachiza kachilombo ka HIV, ikhoza kuchepetsa mwayi wanu wopeza matenda a immunodeficiency syndrome (AIDS) ndi matenda okhudzana ndi HIV monga matenda akulu kapena khansa. Kumwa mankhwalawa pamodzi ndi kugonana mosatekeseka ndikusintha zina pamoyo wanu kumachepetsa chiopsezo chotenga (kufalitsa) kachirombo ka HIV kwa anthu ena.

Raltegravir imabwera ngati piritsi, piritsi losasunthika, komanso timagulu tomwe timayimitsidwa pakamwa kuti titenge pakamwa. Raltegravir (Isentress^®) mapiritsi, mapiritsi osasunthika, komanso kuyimitsidwa pakamwa nthawi zambiri amatengedwa kapena opanda chakudya kawiri patsiku. Raltegravir (Isentress^® HD) mapiritsi nthawi zambiri amatengedwa popanda chakudya kamodzi patsiku. Tengani raltegravir nthawi yofanana tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani raltegravir ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi lonse; osagawana, kutafuna, kapena kuwaphwanya. Ngati mukumwa mapiritsi otetemera, mutha kuwatafuna kapena kuwameza onse.

Kwa ana omwe amavutika kutafuna, mapiritsi otetemera amatha kuphwanyidwa ndikusakanizidwa ndi supuni 1 (5 ml) yamadzi monga madzi, msuzi, kapena mkaka wa m'mawere mu kapu yoyera. Mapiritsiwo amayamwa madziwo ndikugwa mkati mwa mphindi ziwiri. Pogwiritsa ntchito supuni, pewani zidutswa zotsalazo. Imwani chisakanizo nthawi yomweyo. Ngati mankhwala aliwonse atsalira mu chikho, onjezerani supuni (5 ml) yamadzi, yothirani madzi ndikutenga nthawi yomweyo.

Musanayambe kumwa raltegravir kuyimitsidwa pakamwa kwa nthawi yoyamba, werengani malangizo olembedwa omwe amafotokoza momwe angakonzekerere mankhwalawa. Sakanizani zomwe zili mu paketi imodzi ya granule mu kapu yosakaniza ndikuwonjezera masupuni 2 (10 mL) amadzi. Sungani bwino zomwe zili mkapu yosakaniza kwa masekondi 45; musagwedezeke. Gwiritsani ntchito syringe ya dosing yoperekedwa kuti muyese kuchuluka kwa mankhwala omwe dokotala wakupatsani. Gwiritsani ntchito chisakanizo mkati mwa mphindi 30 kukonzekera ndikukataya kuyimitsidwa kulikonse.

Pitilizani kumwa raltegravir ngakhale mukumva bwino. Osasiya kumwa raltegravir kapena mankhwala ena a anti-HIV osalankhula ndi dokotala. Mukasiya kumwa raltegravir kapena kudumpha mlingo, matenda anu akhoza kukulirakulira ndipo kachilomboka kakhoza kugonjetsedwa ndi mankhwala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge raltegravir,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi raltegravir, mankhwala ena aliwonse, kapena zosakaniza zilizonse za mankhwala a raltegravir. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: maantacid okhala ndi calcium, magnesium, kapena aluminium (Maalox, Mylanta, Tums, ndi ena); carbamazepine (Equetro, Tegretol, Teril); mankhwala ochepetsa mafuta m'thupi (ma statins) monga atorvastatin (Lipitor, ku Caduet), fluvastatin (Lescol), lovastatin (Altoprev), pravastatin (Pravachol), rosuvastatin (Crestor), ndi simvastatin (Zocor, ku Vytorin); etravirine (Kutengeka); fenofibrate (Antara, Lipofen, Tricor, ena); gemfibrozil (Lopid); phenobarbital; phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater), tipranavir (Aptivus) ndi ritonavir (Norvir); ndi zidovudine (Retrovir, ena). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• Uzani dokotala wanu ngati mukumupatsa mankhwala a dialysis (chithandizo chamankhwala kuti muyeretsedwe magazi ngati impso sizikugwira ntchito moyenera), kapena ngati mwakhalapo ndi hepatitis, cholesterol yamagazi kapena triglycerides (mafuta am'magazi), matenda amisempha kapena kutupa kwa minofu, kapena rhabdomyolysis (chigoba cha minofu).
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Mukakhala ndi pakati mukatenga raltegravir, itanani dokotala wanu. Uzani dokotala wanu ngati mukuyamwitsa kapena mukufuna kuyamwitsa. Simuyenera kuyamwa ngati muli ndi kachilombo ka HIV kapena ngati mukumwa raltegravir.
• ngati muli ndi phenylketonuria (PKU, mkhalidwe wobadwa nawo momwe muyenera kudya chakudya chapadera kuti muchepetse kuchepa kwamaganizidwe), muyenera kudziwa kuti mapiritsi osavuta omwe ali ndi aspartame omwe amapanga phenylalanine.
• muyenera kudziwa kuti pamene mukumwa mankhwala ochizira kachilombo ka HIV, chitetezo chanu cha mthupi chingakhale champhamvu ndikuyamba kulimbana ndi matenda ena omwe anali kale mthupi lanu. Izi zitha kukupangitsani kukhala ndi zizindikilo za matendawa. Ngati muli ndi zizindikiro zatsopano kapena zowonjezereka mukamalandira raltegravir.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musamamwe mapiritsi awiri a raltegravir nthawi yomweyo kuti mupange mankhwala omwe mwaphonya.

Raltegravir ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutsegula m'mimba
• mpweya
• kupweteka m'mimba
• kutentha pa chifuwa
• kusowa tulo
• maloto achilendo
• kukhumudwa
• mutu

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• kupweteka kwa minofu kapena kufatsa
• kufooka kwa minofu
• mkodzo wakuda kapena kola
• kupweteka pachifuwa kapena kupanikizika
• zidzolo
• malungo
• zotupa pakhungu kapena khungu
• ming'oma
• kuyabwa
• kutupa kwa maso, nkhope, milomo, lilime, mmero, manja, mapazi, akakolo, kapena mikono
• kuvuta kupuma kapena kumeza
• kutopa kwambiri
• zotupa pakamwa
• ofiira, oyabwa, kapena otupa
• kupweteka kumtunda chakumanja kwam'mimba
• chikasu cha khungu kapena maso
• mipando yotumbululuka
• nseru
• kusanza
• kusowa chilakolako
• kugunda kwamtima mwachangu
• kupuma movutikira
• malungo, zilonda zapakhosi, chifuwa, kuzizira, ndi zizindikiro zina za matenda
• kusowa mphamvu
• kunenepa kopanda tanthauzo
• kuchepa kwa mkodzo
• kutupa mozungulira mapazi, akakolo, kapena miyendo
• Kusinza

Raltegravir ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Musachotse desiccant (paketi yaying'ono yophatikizidwa ndi mapiritsi oyamwa chinyezi) kuchokera mu botolo lanu.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Sungani maimidwe onse ndi dokotala komanso labotale mukamamwa raltegravir. Dokotala wanu adzaitanitsa mayeso ena a labu kuti muwone momwe thupi lanu limayankhira ku raltegravir.

Musalole kuti aliyense azimwa mankhwala anu.

Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Isentress^®
• Isentress^® HD