Jekeseni wa Bendamustine

Zamkati

• Asanalandire jekeseni wa bendamustine,
• Kubaya kwa Bendamustine kumatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:
• Zizindikiro za bongo zingaphatikizepo:

Jekeseni ya Bendamustine imagwiritsidwa ntchito pochiza khansa ya m'magazi (CLL; mtundu wa khansa yamagazi oyera). Jekeseni ya Bendamustine imagwiritsidwanso ntchito pochiza mtundu wa Hodgkins lymphoma (NHL: khansa yomwe imayamba ndi mtundu wamagazi oyera omwe amalimbana ndi matenda) omwe amafalikira pang'onopang'ono, koma akupitilirabe kukulirakulira mukamalandira mankhwala ena. Bendamustine ali mgulu la mankhwala otchedwa alkylating agents. Zimagwira ntchito popha ma cell omwe amapezeka ndi khansa ndikuchepetsa kukula kwa ma cell a khansa.

Bendamustine amabwera ngati yankho (madzi) kapena ngati ufa wothira madzi ndikubaya jakisoni (mu mtsempha) kupitilira mphindi 10 kapena kulowetsedwa mkati mwa mphindi 30 kapena 60 ndi adotolo kapena namwino kuofesi ya zamankhwala kapena kuchipatala cha odwala kuchipatala. Pamene jekeseni ya bendamustine imagwiritsidwa ntchito pochizira CLL, nthawi zambiri imabayidwa kamodzi patsiku kwa masiku awiri, kenako masiku 26 pomwe mankhwalawo sanaperekedwe. Nthawi yamankhwala iyi imatchedwa kuzungulira, ndipo kuzungulira kumatha kubwerezedwa masiku aliwonse 28 kwa nthawi yayitali 6. Pamene jekeseni ya bendamustine imagwiritsidwa ntchito kuchiza NHL, nthawi zambiri imabayidwa kamodzi patsiku kwa masiku awiri, kenako masiku 19 pomwe mankhwalawo sanaperekedwe. Izi zimachitika mobwerezabwereza masiku 21 aliwonse mpaka nthawi zisanu ndi zitatu.

Dokotala wanu angafunikire kuchedwetsa chithandizo chanu ndikusintha mulingo wanu mukakumana ndi zovuta zina. Dokotala wanu amathanso kukupatsani mankhwala ena kuti muteteze kapena kuchiza zovuta zina. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira chithandizo cha jakisoni wa bendamustine.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire jekeseni wa bendamustine,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la bendamustine, mankhwala ena aliwonse, kapena zosakaniza zilizonse za jekeseni ya bendamustine. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: ciprofloxacin (Cipro), fluvoxamine (Luvox, ndi omeprazole (Prilosec). Dokotala wanu angafunike kusintha mlingo wa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amatha kulumikizana ndi bendamustine , onetsetsani kuti mwauza dokotala wanu za mankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• Uzani dokotala wanu ngati mwakhalapo ndi matenda a cytomegalovirus (CMV; matenda opatsirana omwe angayambitse odwala omwe ali ndi chitetezo chamthupi chofooka), matenda a kachilombo ka hepatitis B (HBV; matenda opatsirana a chiwindi), chifuwa chachikulu (TB; matenda akulu zomwe zimakhudza mapapo ndipo nthawi zina mbali zina za thupi), herpes zoster (shingles; zotupa zomwe zimatha kuchitika kwa anthu omwe adakhalapo ndi nthomba m'mbuyomu), kapena matenda a impso kapena chiwindi.
• uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati, kapena ngati mukufuna kukhala ndi mwana. Inu kapena mnzanu simuyenera kutenga pakati pomwe mukulandira jekeseni wa bendamustine. Muyenera kugwiritsa ntchito njira zakulera kuti mupewe kutenga pakati panu kapena mnzanu mukamamwa mankhwala a bendamustine komanso kwa miyezi itatu pambuyo pake. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Ngati inu kapena mnzanu mumakhala ndi pakati mukalandira jekeseni wa bendamustine, itanani dokotala wanu. Jekeseni wa Bendamustine itha kuvulaza mwana wosabadwayo.
• uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa mukamamwa mankhwala ndi bendamustine.
• muyenera kudziwa kuti jekeseni wa bendamustine imatha kukutopetsani. Osayendetsa galimoto kapena kugwiritsa ntchito makina mpaka mutadziwa momwe mankhwalawa amakukhudzirani.
• uzani dokotala ngati mumagwiritsa ntchito fodya. Kusuta kumatha kuchepetsa mphamvu ya mankhwalawa.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Itanani dokotala wanu nthawi yomweyo ngati simungathe kusungitsa nthawi yokumana kuti mulandire jakisoni wa bendamustine.

Kubaya kwa Bendamustine kumatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kutsegula m'mimba
• kutentha pa chifuwa
• kudzimbidwa
• kupweteka m'mimba kapena kutupa
• zilonda kapena zigamba zoyera pakamwa
• pakamwa pouma
• kusakoma pakamwa kapena kuvutikira kulawa chakudya
• kusowa chilakolako
• kuonda
• mutu
• nkhawa
• kukhumudwa
• kuvuta kugona kapena kugona
• msana, fupa, olowa, mkono kapena kupweteka kwa mwendo
• khungu lowuma
• thukuta
• thukuta usiku

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• kupweteka pamalo pomwe mankhwala adayikidwa
• ming'oma
• zidzolo
• kuyabwa
• khungu kapena khungu
• kuvuta kupuma kapena kumeza
• kutupa kwa maso, nkhope, milomo, lilime, mikono, manja, mapazi, akakolo, kapena miyendo yakumunsi
• kupuma movutikira
• kupweteka pachifuwa
• kugunda kwamtima mwachangu
• kutopa kwambiri kapena kufooka
• khungu lotumbululuka
• malungo, kuzizira, chifuwa, kapena zizindikiro zina za matenda
• nseru; kusanza; kutuluka mwachilendo kapena kuvulala; chikasu cha khungu kapena maso, mkodzo wakuda, kapena chopondapo choyera; Chikondi kumanja chakumanja chakumimba

Kubayira kwa Bendamustine kumatha kubweretsa kusabereka mwa amuna ena. Kusabereka kumeneku kumatha atatha chithandizo, kumatha zaka zingapo, kapena kumatha. Lankhulani ndi dokotala wanu za kuopsa kolandira mankhwalawa.

Anthu ena adayamba mitundu ina ya khansa pomwe amagwiritsa ntchito jakisoni wa bendamustine. Palibe chidziwitso chokwanira kudziwa ngati jakisoni wa bendamustine adayambitsa khansa iyi. Lankhulani ndi dokotala wanu za kuopsa kolandira mankhwalawa.

Kubaya kwa Bendamustine kumatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• kugunda kwamtima msanga, kosasinthasintha, kapena kwamphamvu

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti aone momwe thupi lanu lingayankhire jakisoni wa bendamustine.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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