Romiplostim jekeseni

Zamkati

• Asanalandire jakisoni wa romiplostim,
• Romiplostim jakisoni angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

Jakisoni wa Romiplostim amagwiritsidwa ntchito kukulitsa kuchuluka kwa ma platelet (maselo omwe amathandiza magazi kuundana) kuti muchepetse kuwopsa kwa magazi mwa achikulire omwe ali ndi immune thrombocytopenia (ITP; idiopathic thrombocytopenic purpura; vuto lomwe lingayambitse kuvulaza kapena kutaya magazi mosavuta chifukwa cha kuchuluka kwamagazi m'magazi). Jakisoni wa Romiplostim umagwiritsidwanso ntchito kukulitsa kuchuluka kwa ma platelet kuti muchepetse mwayi wopezeka magazi kwa ana osachepera chaka chimodzi omwe akhala ndi ITP kwa miyezi isanu ndi umodzi. Jekeseni ya Romiplostim iyenera kugwiritsidwa ntchito kwa akulu ndi ana azaka 1 kapena kupitilira apo omwe sangachiritsidwe kapena sanathandizidwe ndi mankhwala ena, kuphatikiza mankhwala ena kapena opaleshoni kuchotsa ndulu. Jekeseni wa Romiplostim sayenera kugwiritsidwa ntchito pochiza anthu omwe ali ndi ma platelet otsika omwe amayamba chifukwa cha myelodysplastic syndrome (gulu lomwe mafupa amatulutsa maselo amwazi omwe amapangika ndipo samatulutsa ma cell amwazi okwanira) kapena zinthu zina zilizonse zomwe zimachepetsa magawo amtundu kupatula ITP. Jakisoni wa Romiplostim amagwiritsidwa ntchito kukulitsa kuchuluka kwa ma platelet okwanira kuti muchepetse magazi, koma sagwiritsidwa ntchito kukulitsa kuchuluka kwa ma platelet pamlingo woyenera. Romiplostim ali mgulu la mankhwala otchedwa thrombopoietin receptor agonists. Zimagwira ntchito popangitsa ma cell am'mafupa kupanga ma platelet ambiri.

Jakisoni wa Romiplostim umabwera ngati ufa woti uzisakanikirana ndi madzi kuti alandire jakisoni (pansi pa khungu) ndi dokotala kapena namwino kuofesi yazachipatala. Nthawi zambiri amabayidwa kamodzi pamlungu.

Dokotala wanu mwina angakuyambitseni pa jakisoni wocheperako wa romiplostim ndikusintha mlingo wanu, osapitilira kamodzi sabata iliyonse. Kumayambiriro kwa chithandizo chanu, dokotala wanu amalamula kuti mukayezetse magazi kuti muwone kuchuluka kwa magazi anu m'mwezi kamodzi sabata iliyonse. Dokotala wanu akhoza kukulitsa mlingo wanu ngati kuchuluka kwa mapuloti anu kutsika kwambiri. Ngati mulingo wanu wamagazi ndiwokwera kwambiri, dokotala wanu akhoza kuchepetsa mlingo wanu kapena sangakupatseni mankhwala konse. Pambuyo poti chithandizo chanu chapitilira kwakanthawi ndipo dokotala wanu wapeza mulingo womwe ukugwirirani ntchito, muyeso wanu wamaplatelet umayang'aniridwa kamodzi pamwezi. Mulingo wanu wa mapuloletti udzawunikiridwa kwa milungu iwiri musanamalize chithandizo chanu ndi jakisoni wa romiplostim.

Jakisoni wa Romiplostim sagwira ntchito kwa aliyense. Ngati mulingo wanu wam'maplatelet ukuwonjezeka mokwanira mutalandira jakisoni wa romiplostim kwakanthawi, dokotala wanu asiya kukupatsani mankhwala. Dokotala wanu amathanso kuyitanitsa mayeso amwazi kuti mudziwe chifukwa chake jakisoni wa romiplostim sunakugwireni.

Romiplostim jakisoni imayang'anira ITP koma siyichiza. Pitirizani kusunga nthawi kuti mulandire jakisoni wa romiplostim ngakhale mutakhala bwino.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba chithandizo ndi jakisoni wa romiplostim. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs) kapena tsamba laopanga kuti mupeze Chithandizo cha Mankhwala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire jakisoni wa romiplostim,

• uzani dokotala wanu komanso wamankhwala ngati simukugwirizana ndi jakisoni wa romiplostim kapena mankhwala ena aliwonse.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: maanticoagulants (ochepetsa magazi) monga warfarin (Coumadin); aspirin ndi mankhwala ena osagwiritsa ntchito kutupa (NSAIDs) monga ibuprofen (Advil, Motrin) ndi naproxen (Aleve, Naprosyn); cilostazol (Pletal); clopidogrel (Plavix); dipyridamole (Aggrenox); heparin; ndi ticlopidine (Ticlid). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi romiplostim, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• Uzani dokotala wanu ngati mwakhalapo ndi magazi kapena mavuto a magazi, khansa yamtundu uliwonse yomwe imakhudza ma cell anu am'magazi, myelodysplastic syndrome (vuto lomwe mafupa amapanga magazi osazolowereka ndipo pali chiopsezo kuti khansa ya Maselo amwazi atha kukhala), vuto lina lililonse lomwe limakhudza mafupa anu, kapena matenda a chiwindi. Muuzeni dokotala ngati wachotsa ndulu yanu.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Mukakhala ndi pakati mukalandira jakisoni wa romiplostim, itanani dokotala wanu.
• uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwitsa mukamamwa jakisoni wa romiplostim.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukulandira jakisoni wa romiplostim.
• pitilizani kupewa zinthu zomwe zitha kuvulaza komanso kutaya magazi mukamamwa jakisoni wa romiplostim. Jekeseni ya Romiplostim imaperekedwa kuti ichepetse chiopsezo choti mudzadwala magazi kwambiri, komabe pali chiopsezo kuti kutuluka magazi kumatha kuchitika.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Itanani dokotala wanu nthawi yomweyo ngati simungathe kusungitsa nthawi yokumana kuti mulandire jakisoni wa romiplostim.

Romiplostim jakisoni angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• mutu
• kulumikizana kapena kupweteka kwa minofu
• kupweteka kwa mikono, miyendo, kapena mapewa
• dzanzi, kutentha, kapena kumva kulasalasa m'manja kapena m'miyendo
• kupweteka m'mimba
• kutentha pa chifuwa
• kusanza
• kutsegula m'mimba
• kuvuta kugona kapena kugona
• kutuluka mphuno, kuchulukana, kutsokomola, kapena matenda ena ozizira
• kupweteka pakamwa kapena pakhosi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

• magazi
• kuvulaza
• kutupa, kupweteka, kukoma mtima, kutentha kapena kufiira mwendo umodzi
• kupuma movutikira
• kutsokomola magazi
• kugunda kwamtima mwachangu
• kupuma mofulumira
• kupweteka mukamapuma kwambiri
• kupweteka pachifuwa, mikono, kumbuyo, khosi, nsagwada, kapena m'mimba
• kutuluka thukuta lozizira
• nseru
• wamisala
• mawu odekha kapena ovuta
• chizungulire kapena kukomoka
• kufooka kapena kufooka kwa mkono kapena mwendo

Jakisoni wa Romiplostim ungayambitse mafupa anu. Kusintha kumeneku kumatha kupangitsa kuti mafupa anu achepetse magazi kapena kuti apange maselo abwinobwino amwazi. Mavuto amwaziwa atha kukhala owopsa.

Jekeseni wa Romiplostim itha kupangitsa kuti maplatelet anu azikula kwambiri. Izi zitha kuwonjezera chiopsezo choti mudzadwala magazi, omwe amatha kufalikira m'mapapu, kapena kuyambitsa matenda amtima kapena sitiroko. Dokotala wanu amayang'anitsitsa kuchuluka kwa mapulozi anu mukamamwa mankhwala a romiplostim.

Mukatha kulandira chithandizo ndi jakisoni wa romiplostim, kuchuluka kwa ma platelet anu kumatsika poyerekeza ndi momwe munalili musanayambe mankhwala anu ndi jakisoni wa romiplostim. Izi zimawonjezera chiopsezo choti mudzakumana ndi mavuto otaya magazi. Dokotala wanu adzakuyang'anirani mosamala kwa masabata awiri mutatha mankhwala anu. Ngati muli ndi zipsera zachilendo kapena magazi, uzani dokotala nthawi yomweyo.

Lankhulani ndi dokotala wanu za kuopsa kolandila jakisoni wa romiplostim.

Romiplostim jakisoni zingayambitse mavuto ena. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti aone momwe thupi lanu lingayankhire jekeseni wa romiplostim.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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