Dexrazoxane jekeseni

Zamkati

• Asanalandire jekeseni wa dexrazoxane,
• Jekeseni wa Dexrazoxane imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:
• Zizindikiro za bongo zingaphatikizepo:

Jekeseni wa Dexrazoxane (Totect, Zinecard) amagwiritsidwa ntchito popewa kapena kuchepetsa kukhuthala kwa minofu yamtima yoyambitsidwa ndi doxorubicin mwa azimayi omwe amamwa mankhwalawa kuti athetse khansa ya m'mawere yomwe yafalikira mbali zina za thupi. Jekeseni wa Dexrazoxane (Totect, Zinecard) imaperekedwa kwa azimayi omwe alandila kale doxorubicin ndipo adzafunika kupitiliza kulandira mankhwala a doxorubicin, sagwiritsidwa ntchito popewa kuwonongeka kwa mtima kwa amayi omwe akuyamba kulandira mankhwala ndi doxorubicin. Jekeseni wa Dexrazoxane (Totect) amagwiritsidwa ntchito pochepetsa kuwonongeka kwa khungu ndi ziphuphu zomwe zingayambike pamene mankhwala a anthracycline chemotherapy monga daunorubicin (Cerubidine), doxorubicin (Adriamycin, Doxil), epirubicin (Ellence) kapena idarubicin (Idamycin) amatuluka mitsempha pamene ikubayidwa. Jekeseni wa Dexrazoxane ili mgulu la mankhwala otchedwa cardioprotectants ndi chemoprotectants. Zimagwira ntchito poletsa mankhwala a chemotherapy kuti asawononge mtima ndi minofu.

Jekeseni wa Dexrazoxane umabwera ngati ufa wosakanizidwa ndi madzi ndikulowetsedwa mumtsinje ndi dokotala kapena namwino kuchipatala. Jekeseni wa dexrazoxane akagwiritsidwa ntchito popewa kuwonongeka kwa mtima chifukwa cha doxorubicin, amapatsidwa mphindi zopitilira 15 kutatsala pang'ono kumwa doxorubicin. Pamene jekeseni wa dexrazoxane imagwiritsidwa ntchito popewa kuwonongeka kwa minofu pambuyo poti mankhwala a anthracycline atuluka mumtsempha, amapatsidwa kupitirira 1 mpaka 2 maola kamodzi patsiku masiku atatu. Mlingo woyamba umaperekedwa mwachangu mkati mwa maola 6 oyamba kutayikira kwatuluka, ndipo mulingo wachiwiri ndi wachitatu amapatsidwa pafupifupi maola 24 ndi 48 pambuyo pa mlingo woyamba.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire jekeseni wa dexrazoxane,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la dexrazoxane, mankhwala aliwonse, kapena zosakaniza zilizonse za jekeseni wa dexrazoxane. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo zinthu zam'mutu za dimethylsulfoxide (DMSO).
• Uzani dokotala wanu ngati mwakhalapo ndi matenda amtima, impso, kapena chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena konzekerani kukhala ndi mwana. Simuyenera kutenga pakati mukalandira jekeseni wa dexrazoxane. Ngati mukulandira jekeseni wa dexrazoxane (Zinecard), muyenera kugwiritsa ntchito njira zakulera mukamalandira chithandizo. Ngati mukulandira jekeseni wa dexrazoxane (Totect), muyenera kugwiritsa ntchito njira zakulera mukamalandira chithandizo komanso kwa miyezi yosachepera 6 mutalandira mankhwala. Ngati ndinu wamwamuna, inu ndi mnzanuyo muyenera kugwiritsa ntchito njira zakulera mukamalandira chithandizo komanso kwa miyezi itatu mutasiya kulandira jakisoni wa dexrazoxane (Totect). Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Ngati inu kapena mnzanu mumakhala ndi pakati mukalandira jakisoni wa dexrazoxane, itanani dokotala wanu. Dexrazoxane atha kuvulaza mwana wosabadwayo.
• uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwitsa mukalandira jekeseni wa dexrazoxane (Zinecard). Ngati mukulandira jekeseni wa dexrazoxane (Totect), simuyenera kuyamwa mukalandira chithandizo komanso kwa milungu iwiri mutalandira mankhwala omaliza.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka mwa amuna. Lankhulani ndi dokotala wanu za kuopsa kolandila jekeseni wa dexrazoxane.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani adotolo kapena dokotala kuti mukulandira jekeseni wa dexrazoxane.
• muyenera kudziwa kuti chithandizo cha jekeseni wa dexrazoxane chimachepa koma sichimathetsa chiopsezo kuti doxorubicin ingawononge mtima wanu. Dokotala wanu adzafunikirabe kukuyang'anirani mosamala kuti muwone momwe doxorubicin yakhudzira mtima wanu.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Jekeseni wa Dexrazoxane imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kupweteka kapena kutupa pamalo pomwe munabayira mankhwala
• nseru
• kusanza
• kutsegula m'mimba
• kudzimbidwa
• kupweteka m'mimba
• kusowa chilakolako
• chizungulire
• mutu
• kutopa kwambiri
• kuvuta kugona kapena kugona
• kukhumudwa
• kutupa kwa mikono, manja, mapazi, akakolo, kapena miyendo yakumunsi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• zilonda zapakhosi, malungo, kuzizira, chifuwa, ndi zizindikilo zina za matenda
• kuvulaza kapena kutuluka mwachilendo
• khungu lotumbululuka
• kufooka
• kupuma movutikira
• zidzolo
• kuyabwa
• ming'oma
• kuvuta kupuma kapena kumeza
• kutupa kwa maso, nkhope, pakamwa, milomo, lilime, kapena pakhosi
• chizungulire
• kukomoka

Anthu ena omwe adamwa mankhwala omwe amafanana kwambiri ndi jekeseni wa dexrazoxane adapanga mitundu yatsopano ya khansa. Palibe chidziwitso chokwanira choti mudziwe ngati kulandira jekeseni wa dexrazoxane kumawonjezera chiopsezo kuti mudzakhala ndi khansa yatsopano. Lankhulani ndi dokotala wanu za kuopsa kolandira mankhwalawa.

Jekeseni wa Dexrazoxane imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• zilonda zapakhosi, malungo, kuzizira, ndi zizindikiro zina za matenda
• kuvulaza kapena kutuluka mwachilendo
• khungu lotumbululuka
• kupuma movutikira
• kutopa kwambiri

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti awone kuyankha kwa thupi lanu ku jakisoni wa dexrazoxane.

Funsani dokotala wanu kapena wamankhwala mafunso aliwonse omwe muli nawo okhudza jekeseni wa dexrazoxane.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Zochepa^®
• Zinecard^®