Apixaban

Zamkati

• Musanatenge apixaban,
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:
• Zizindikiro za bongo zingaphatikizepo izi:

Ngati muli ndi matenda a atrial fibrillation (momwe mtima umagunda mosalekeza, kukulitsa mwayi wam'magazi wopangidwa mthupi, ndipo mwina kuyambitsa sitiroko) ndipo mukumwa apixaban kuti muteteze sitiroko kapena kuundana kwamagazi, muli pachiwopsezo chachikulu kudwala sitiroko mutasiya kumwa mankhwalawa. Osasiya kumwa apixaban osalankhula ndi dokotala. Pitirizani kutenga apixaban ngakhale mukumva bwino. Onetsetsani kuti mukudzaza mankhwala anu musanathe mankhwala kuti musaphonye mlingo wa apixaban. Ngati mukufuna kusiya kumwa apixaban, dokotala wanu akhoza kukupatsani mankhwala ena oletsa anticoagulant ('magazi ochepera magazi') kuti ateteze magazi oundana kuti asapangidwe ndikupatseni sitiroko.

Ngati muli ndi matenda opatsirana kapena otupa msana kapena kuboola msana mukamamwa 'magazi ocheperako' monga apixaban, muli pachiwopsezo chokhala ndi mawonekedwe a magazi mkati kapena mozungulira msana wanu zomwe zingakupangitseni kukhala wolumala. Uzani dokotala wanu ngati muli ndi catheter yamatenda yomwe yatsala m'thupi lanu kapena mwakhalapo ndi zotupa zingapo zam'mimba kapena zopindika msana, kuwonongeka kwa msana, kapena opaleshoni ya msana. Uzani dokotala wanu komanso wamankhwala ngati mukumwa izi: anagrelide (Agrylin); aspirin ndi mankhwala ena osagwiritsa ntchito kutupa (NSAIDs) monga ibuprofen (Advil, Motrin, ena), indomethacin (Indocin, Tivorbex), ketoprofen, ndi naproxen (Aleve, Anaprox, ena); cilostazol (Pletal); clopidogrel (Plavix); dipyridamole (Persantine); eptifibatide (Integrilin); heparin; prasugrel (Mphamvu); maphunziro (Brilinta); ticlopidine; tirofiban (Aggrastat), ndi warfarin (Coumadin, Jantoven). Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo: kufooka kwa minofu (makamaka m'miyendo ndi m'miyendo), kufooka kapena kumva kulira (makamaka m'miyendo), kapena kulephera kuwongolera matumbo kapena chikhodzodzo.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Chithandizo cha Mankhwala) mukayamba mankhwala ndi apixaban ndipo nthawi iliyonse mukamadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Lankhulani ndi dokotala wanu za kuopsa kotenga apixaban.

Apixaban imagwiritsidwa ntchito kuthandizira kupwetekedwa kapena magazi m'magazi mwa anthu omwe ali ndi matenda a atrial fibrillation (vuto lomwe mtima umagunda mosalekeza, ndikuwonjezera mwayi wamatumba opangidwa mthupi ndipo mwina kuyambitsa zilonda) zomwe sizimayambitsidwa ndi matenda a valavu yamtima. Apixaban imagwiritsidwanso ntchito kupewetsa mitsempha yakuya kwambiri (DVT; magazi, nthawi zambiri mwendo) ndi kupindika kwa m'mapapo (PE; magazi m'mapapo) mwa anthu omwe akuchita opaleshoni ya mchiuno kapena maondo. Apixaban imagwiritsidwanso ntchito pochiza DVT ndi PE ndipo itha kupitilizidwa kuteteza DVT ndi PE kuti zisadzachitikenso mankhwala oyamba akamalizidwa. Apixaban ali mgulu la mankhwala otchedwa factor Xa inhibitors. Zimagwira ntchito poletsa kuchitapo kanthu kwachilengedwe komwe kumathandizira kuundana kwamagazi.

Apixaban amabwera ngati piritsi kuti atenge pakamwa. Nthawi zambiri amatengedwa kapena wopanda chakudya kawiri patsiku. Apixaban ikatengedwa kuti iteteze DVT ndi PE pambuyo pa opaleshoni ya m'chiuno kapena mawondo, mlingo woyamba uyenera kutengedwa osachepera 12 mpaka 24 maola atachitidwa opaleshoni. Apixaban nthawi zambiri amatengedwa masiku 35 atachitidwa opareshoni m'chiuno komanso masiku 12 atachitidwa opaleshoni yamondo. Tengani apixaban mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani apixaban ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Ngati mukulephera kumeza mapiritsiwo, mutha kuwaphwanya ndikusakanikirana ndi madzi, msuzi wa apulo, kapena maapulosi. Kumeza chisakanizo mutangokonzekera. Apixaban itha kuperekedwanso mumitundu ina yamachubu zodyetsa. Funsani dokotala ngati mukuyenera kumwa mankhwalawa mu chubu chanu chodyetsera. Tsatirani malangizo a dokotala mosamala.

Pitirizani kutenga apixaban ngakhale mukumva bwino. Osasiya kumwa apixaban osalankhula ndi dokotala. Mukasiya kumwa apixaban, chiopsezo chanu chokhala ndi magazi chitha kukulirakulira.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge apixaban,

• uzani dokotala ndi wamankhwala ngati muli ndi vuto la apixaban, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a apixaban. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ena omwe simukupatsidwa, mavitamini, ndi zowonjezera zakudya zomwe mukumwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); clarithromycin (Biaxin, mu Prevpac); itraconazole (Onmel, Sporanox); ketoconazole (Nizoral); phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rimactane, ku Rifadin, ku Rifater); ritonavir (Norvir, ku Kaletra); serotonin reuptake inhibitors (SSRIs) monga citalopram (Celexa), fluoxetine (Prozac, Sarafem, Selfemra, mu Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), ndi sertraline (Zoloft); ndi serotonin ndi norepinephrine reuptake inhibitors (SNRIs) monga duloxetine (Cymbalta), desvenlafaxine (Khedezla, Pristiq), milnacipran (Fetzima, Savella), ndi venlafaxine (Effexor). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi apixaban, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• muyenera kudziwa kuti apixaban amatha kulumikizana ndi mankhwala ena omwe atha kugwiritsidwa ntchito ngati mutapwetekedwa kapena mwadzidzidzi. Ngati mwadzidzidzi, inu kapena wachibale wanu muyenera kuuza adotolo kapena ogwira ntchito kuchipatala omwe akukuthandizani kuti mukumwa apixaban.
• uzani dokotala wanu ngati muli ndi valavu yopangira mtima kapena ngati muli ndi magazi ochulukirapo kulikonse m'thupi lanu omwe sangathe kuyimitsidwa. Dokotala wanu angakuuzeni kuti musatenge apixaban.
• uzani dokotala wanu ngati mwakhalapo ndi vuto lililonse lotuluka magazi, antiphospholipid syndrome (APS; vuto lomwe limayambitsa kuundana kwamagazi), kapena matenda a impso kapena chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga apixaban, itanani dokotala wanu.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa apixaban. Dokotala wanu angakuuzeni kuti musiye kumwa apixaban musanachite opaleshoni kapena njira. Ngati mukufuna kusiya kumwa apixaban chifukwa mukuchitidwa opaleshoni, dokotala wanu akhoza kukupatsani mankhwala osiyanasiyana kuti ateteze magazi nthawi imeneyi. Dokotala wanu angakuuzeni nthawi yomwe muyenera kuyambiranso apixaban mukatha opaleshoni. Tsatirani malangizowa mosamala.
• Itanani dokotala wanu nthawi yomweyo ngati mukugwa kapena kudzivulaza, makamaka mukamenya mutu. Dokotala wanu angafunike kuti akuyese.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• nkhama zotuluka magazi
• mwazi wa m'mphuno
• kutuluka magazi kwambiri kumaliseche
• mkodzo wofiira, pinki, kapena bulauni
• ofiira kapena akuda, mipando yodikira
• kutsokomola kapena kusanza magazi kapena zinthu zomwe zimawoneka ngati malo a khofi
• kutupa kapena kupweteka pamfundo
• mutu
• zidzolo
• kupweteka pachifuwa kapena kulimba
• kutupa kwa nkhope kapena lilime
• kuvuta kupuma
• kupuma
• kumva chizungulire kapena kukomoka

Apixaban imalepheretsa magazi kuti atseke bwino, chifukwa zimatha kutenga nthawi yayitali kuposa nthawi zonse kuti musiye magazi mukadulidwa kapena kuvulala. Mankhwalawa amathanso kukupweteketsani kapena kutuluka magazi mosavuta. Itanani dokotala wanu nthawi yomweyo ngati kutuluka magazi kapena kuvulaza kuli kwachilendo, koopsa, kapena kosalamulirika.

Apixaban ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisunge kutentha komanso kutali ndi kuwala, kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kutuluka mwachilendo kapena kuphwanya
• mkodzo wofiira, wabulauni, kapena pinki
• ofiira kapena akuda, mipando yodikira
• kutsokomola kapena kusanza magazi kapena zinthu zomwe zimawoneka ngati malo a khofi

Sungani maimidwe onse ndi dokotala wanu.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Eliquis^®