Empagliflozin
Zamkati
- Asanatenge empagliflozin,
- Mankhwalawa amatha kusintha shuga m'magazi anu. Muyenera kudziwa zizindikiro za shuga wotsika kwambiri komanso zomwe muyenera kuchita ngati muli ndi izi.
- Empagliflozin angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
- Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:
- Ngati mukumane ndi izi, lekani kumwa empagliflozin ndipo itanani dokotala mwachangu kapena mupeze chithandizo chadzidzidzi:
- Ngati mukumane ndi zizindikiro zotsatirazi za ketoacidosis, lekani kumwa empagliflozin ndipo itanani dokotala mwamsanga kapena pitani kuchipatala mwadzidzidzi. Ngati kuli kotheka, fufuzani ketoni mumkodzo wanu ngati muli ndi zizindikirozi, ngakhale shuga lanu la magazi liri lochepera 250 mg / dL:
Empagliflozin imagwiritsidwa ntchito limodzi ndi zakudya komanso kuchita masewera olimbitsa thupi, ndipo nthawi zina ndi mankhwala ena, kuti muchepetse shuga m'magazi mwa anthu omwe ali ndi matenda a shuga a mtundu wachiwiri (momwe shuga wamagazi amakhala wochuluka kwambiri chifukwa thupi silimatulutsa kapena kugwiritsa ntchito insulini mwachizolowezi). Empagliflozin imagwiritsidwanso ntchito pochepetsa chiopsezo cha sitiroko, matenda amtima, kapena kufa kwa anthu omwe ali ndi matenda ashuga amtundu wa 2 komanso matenda amtima ndi mtsempha wamagazi. Ali mgulu la mankhwala otchedwa sodium-glucose co-transporter 2 (SGLT2) inhibitors. Empagliflozin imachepetsa shuga wamagazi poyambitsa impso kuchotsa shuga wambiri mkodzo. Sigwiritsidwe ntchito pochiza matenda amtundu woyamba 1 (momwe thupi silimatulutsa insulini, chifukwa chake, silingathe kuwongolera kuchuluka kwa shuga m'magazi) kapena matenda ashuga ketoacidosis (vuto lalikulu lomwe lingachitike ngati shuga wa magazi sakuchiritsidwa ).
Popita nthawi, anthu omwe ali ndi matenda ashuga komanso shuga wambiri m'magazi amatha kukhala ndi mavuto owopsa kapena owopsa, kuphatikizapo matenda amtima, sitiroko, mavuto a impso, kuwonongeka kwa mitsempha, komanso mavuto amaso. Kumwa mankhwala (mankhwala), kusintha moyo wanu (mwachitsanzo, zakudya, kuchita masewera olimbitsa thupi, kusiya kusuta), komanso kuwunika shuga wanu wamagazi pafupipafupi kungakuthandizeni kuthana ndi matenda anu ashuga komanso kukhala ndi thanzi labwino. Mankhwalawa amathanso kuchepetsa mwayi wokhala ndi vuto la mtima, sitiroko, kapena zovuta zina zokhudzana ndi matenda ashuga monga impso kulephera, kuwonongeka kwamitsempha (dzanzi, miyendo yozizira kapena mapazi; kuchepa kwa kugonana kwa amuna ndi akazi), mavuto amaso, kuphatikiza kusintha kutaya masomphenya, kapena matenda a chiseyeye. Dokotala wanu ndi ena othandizira zaumoyo adzakambirana nanu za njira yabwino yothetsera matenda anu ashuga.
Empagliflozin imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku m'mawa kapena wopanda chakudya. Tengani empagliflozin mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani empagliflozin monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.
Dokotala wanu akhoza kukuyambitsani pamlingo wochepa wa empagliflozin ndikuwonjezera mlingo wanu pakufunika kutero.
Empagliflozin amawongolera matenda amtundu wa 2 koma samachiritsa. Pitirizani kutenga empagliflozin ngakhale mutakhala bwino. Osasiya kumwa empagliflozin osalankhula ndi dokotala.
Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.
Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.
Asanatenge empagliflozin,
- uzani dokotala wanu komanso wamankhwala kuti ngati muli ndi vuto la empagliflozin, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a empagliflozin. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
- auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: zoletsa ma angiotensin zotembenuza enzyme (ACE) monga benazepril (Lotensin, ku Lotrel), captopril, enalapril (Vasotec, in Vaseretic), fosinopril, lisinopril (mu Zestoretic), moexipril (Univasc, Uniretic), perindopril (Aceon, ku Prestalia), quinapril (Accupril, mu Accuretic, mu Quinaretic), ramipril (Altace), ndi trandolapril (Mavik, ku Tarka); angiotensin receptor blockers monga azilsartan (Edarbi, ku Edarbyclor), candesartan (Atacand, ku Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, ku Avalide), losartan (Cozaar, ku Hyzaar), olmesartan (Benicar, ku Azor, Azor, ku Benicar HCT, ku Tribenzor), telmisartan (Micardis, ku Micardis HCT, ku Twynsta), ndi valsartan (Diovan, ku Diovan HCT, ku Exforge); aspirin ndi mankhwala ena osagwiritsa ntchito kutupa (NSAIDs) monga ibuprofen (Advil, Motrin) ndi naproxen (Aleve, Naprosyn); digoxin (Lanoxin); okodzetsa ('mapiritsi amadzi'); kapena insulini kapena mankhwala akumwa ashuga monga chlorpropamide (Diabinese), glimepiride (Amaryl, ku Duetact), glipizide (Glucotrol), glyburide (DiaBeta, Glynase, ku Glucovance), tolazamide, ndi tolbutamide. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
- uzani dokotala wanu ngati muli ndi dialysis komanso ngati mwakhalapo ndi matenda a impso. Dokotala wanu angakuuzeni kuti musatenge empagliflozin.
- uzani dokotala wanu ngati mumamwa mowa nthawi zonse kapena nthawi zina mumamwa mowa wambiri nthawi yochepa (kumwa mopitirira muyeso) kapena mumadya zakudya zochepa. Komanso, uzani dokotala ngati mwakhalapo ndi matenda opatsirana mumkodzo kapena mavuto okodza, kuthamanga kwa magazi, cholesterol, kulephera kwa mtima, matenda am'mimba kuphatikizapo kapamba (kutupa kwa kapamba) kapena mwachitidwapo opaleshoni kapamba, matenda a yisiti m'dera loberekera, kapena matenda a chiwindi. Ngati ndinu amuna, uzani dokotala ngati simunadulidwepo. Uzani dokotala wanu ngati mukudya pang'ono chifukwa cha matenda, opaleshoni, kapena kusintha kwa zakudya zanu kapena ngati simungathe kudya kapena kumwa kawirikawiri chifukwa cha mseru, kusanza, kutsegula m'mimba, kapena ngati mwasowa madzi chifukwa chokhala padzuwa nthawi yayitali .
- Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Osamayamwa mukamwa empagliflozin. Mukakhala ndi pakati mukatenga empagliflozin, itanani dokotala wanu.
- ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa empagliflozin.
- mowa ungayambitse kusintha kwa magazi. Funsani dokotala wanu za zakumwa zoledzeretsa pamene mukumwa canagliflozin.
- muyenera kudziwa kuti empagliflozin imatha kuyambitsa chizungulire, mutu wopepuka, komanso kukomoka mukadzuka mwachangu pamalo abodza. Ngati muli ndi vutoli, itanani dokotala wanu. Vutoli limafala kwambiri mukayamba kumwa empagliflozin. Pofuna kupewa vutoli, tulukani pabedi pang'onopang'ono, ndikupumitsa mapazi anu pansi kwa mphindi zingapo musanayimirire
- funsani dokotala wanu choti muchite mukadwala, mutenga matenda kapena malungo, mukumva kupsinjika kwachilendo, kapena mukavulala. Izi zimatha kukhudza shuga wamagazi komanso kuchuluka kwa empagliflozin komwe mungafune.
Onetsetsani kuti mukutsatira zolimbitsa thupi komanso malingaliro azakudya zomwe adokotala anu kapena odyetsa. Ndikofunika kudya zakudya zopatsa thanzi komanso kuchita masewera olimbitsa thupi nthawi zonse. Tsatirani malangizo a dokotala anu zakumwa madzi okwanira tsiku lonse mukamamwa mankhwalawa.
Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.
Mankhwalawa amatha kusintha shuga m'magazi anu. Muyenera kudziwa zizindikiro za shuga wotsika kwambiri komanso zomwe muyenera kuchita ngati muli ndi izi.
Empagliflozin angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
- kukodza kwambiri, kuphatikizapo usiku
- ludzu lowonjezeka
Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:
- kukodza pafupipafupi, mwachangu, kuwotcha, kapena kupweteka
- mkodzo womwe mitambo, yofiira, pinki, kapena bulauni
- m'chiuno kapena kupweteka kwa msana
- (mwa akazi) kununkhira kwa ukazi, kumaliseche koyera kapena koterako (kumatha kukhala kotupa kapena kuwoneka ngati kanyumba kanyumba), kapena kuyabwa kumaliseche
- (mwa amuna) kufiira, kuyabwa, kapena kutupa kwa mbolo; zidzolo pa mbolo; kutuluka koyipa kuchokera ku mbolo; kapena kupweteka pakhungu lozungulira mbolo
- kumva kutopa, kufooka, kapena kusakhazikika; pamodzi ndi malungo ndi ululu, kukoma mtima, kufiira, ndi kutupa kwa maliseche kapena malo apakati pa maliseche ndi thumbo
- zizindikiro ngati chimfine
Ngati mukumane ndi izi, lekani kumwa empagliflozin ndipo itanani dokotala mwachangu kapena mupeze chithandizo chadzidzidzi:
- zidzolo
- ming'oma
- kuyabwa
- zovuta kumeza kapena kupuma
- kutupa kwa nkhope, mmero, lilime, milomo, pakamwa, kapena maso
- ukali
Ngati mukumane ndi zizindikiro zotsatirazi za ketoacidosis, lekani kumwa empagliflozin ndipo itanani dokotala mwamsanga kapena pitani kuchipatala mwadzidzidzi. Ngati kuli kotheka, fufuzani ketoni mumkodzo wanu ngati muli ndi zizindikirozi, ngakhale shuga lanu la magazi liri lochepera 250 mg / dL:
- nseru
- kusanza
- kupweteka kwa m'mimba
- kutopa
- kuvuta kupuma
Empagliflozin ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.
Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).
Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).
Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org
Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.
Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.
Sungani maimidwe onse ndi dokotala wanu ndi labotale. Magazi anu a shuga amayenera kuyang'aniridwa pafupipafupi kuti mudziwe momwe mungayankhire kwa empagliflozin. Dokotala wanu adzaitanitsa mayeso ena a labu, kuphatikiza glycosylated hemoglobin (HbA1c), kuti muwone yankho lanu ku empagliflozin. Dokotala wanu adzakuwuzani momwe mungayang'anire kuyankha kwanu kwa mankhwalawa poyeza kuchuluka kwa shuga wamagazi kunyumba. Tsatirani malangizowa mosamala.
Musanapite kukayezetsa labotale, auzeni adotolo ndi ogwira nawo ntchito kuti mukumwa empagliflozin. Chifukwa cha momwe mankhwalawa amagwirira ntchito, mkodzo wanu ukhoza kuyesa kuti mukhale ndi shuga.
Muyenera kuvala chibangili chizindikiritso cha ashuga kuti mutsimikizire kuti mumalandira chithandizo chadzidzidzi pakagwa mwadzidzidzi.
Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.
Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.
- Makhalidwe®
- Glyxambi® (ngati chinthu chophatikiza chophatikiza Empagliflozin ndi Linagliptin)
- Kusinkhasinkha® (monga chinthu chophatikiza chophatikiza Empagliflozin ndi Metformin)