Mlembi: Virginia Floyd
Tsiku La Chilengedwe: 6 Ogasiti 2021
Sinthani Tsiku: 14 Novembala 2024
Anonim
Edoxaban for Cancer-Associated Venous Thromboembolism
Kanema: Edoxaban for Cancer-Associated Venous Thromboembolism

Zamkati

Ngati muli ndi matenda a atrial fibrillation (momwe mtima umagunda mosalekeza, kuwonjezera mwayi wam'magazi wopangidwa mthupi, mwinanso kuchititsa zikwapu) ndipo mukumwa edoxaban kuti muteteze kupwetekedwa kapena magazi oundana, muli pachiwopsezo chachikulu cha kudwala sitiroko mutasiya kumwa mankhwalawa. Osasiya kumwa edoxaban osalankhula ndi dokotala. Pitirizani kutenga edoxaban ngakhale mutakhala bwino. Onetsetsani kuti mwadzaza mankhwala anu musanathe mankhwala kuti musaphonye mlingo uliwonse wa edoxaban. Ngati mukufuna kusiya kumwa edoxaban, dokotala wanu akhoza kukupatsani mankhwala ena oletsa anticoagulant ('' magazi ochepera magazi '') kuti ateteze magazi kuti asapangike ndikupatseni sitiroko.

Ngati muli ndi matenda opatsirana kapena operewera msana kapena kuboola msana mukamamwa 'magazi ocheperako' monga edoxaban, muli pachiwopsezo chokhala ndi mawonekedwe a magazi mkati kapena mozungulira msana wanu zomwe zingakupangitseni kukhala wolumala. Uzani dokotala wanu ngati muli ndi catheter yamatenda yomwe yatsala m'thupi lanu kapena mwakhalapo ndi zotupa zingapo zam'mimba kapena zopindika msana, kuwonongeka kwa msana, kapena opaleshoni ya msana. Uzani dokotala wanu komanso wamankhwala ngati mukugwiritsa ntchito anagrelide (Agrylin); aspirin ndi mankhwala ena osagwiritsa ntchito kutupa (NSAIDs) monga ibuprofen (Advil, Motrin, ena), indomethacin (Indocin, Tivorbex), ketoprofen, ndi naproxen (Aleve, Anaprox, ena); cilostazol (Pletal); clopidogrel (Plavix); dipyridamole (Persantine); eptifibatide (Integrilin); heparin; prasugrel (Mphamvu); maphunziro (Brilinta); ticlopidine; tirofiban (Aggrastat), ndi warfarin (Coumadin, Jantoven). Ngati mukumane ndi izi, itanani dokotala wanu nthawi yomweyo: kupweteka kwa msana, kufooka kwa minofu, kufooka kapena kugwedezeka (makamaka m'miyendo), kulephera kuwongolera matumbo anu kapena chikhodzodzo, kapena kulephera kusuntha miyendo yanu.


Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu adzayitanitsa mayeso kuti muwone momwe impso zanu zikugwirira ntchito kale komanso nthawi ndi nthawi mukamalandira edoxaban.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Chithandizo cha Mankhwala) mukayamba mankhwala ndi edoxaban ndipo nthawi iliyonse mukadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/downloads/Drugs/DrugSafety/) kapena tsamba laopanga kuti mupeze Chithandizo cha Mankhwala.

Lankhulani ndi dokotala wanu za chiopsezo chotenga edoxaban.

Edoxaban imagwiritsidwa ntchito kuthandizira kupwetekedwa kapena magazi m'magazi mwa anthu omwe ali ndi matenda a atrial fibrillation (vuto lomwe mtima umagunda mosalekeza, ndikuwonjezera mwayi wamatumba opangidwa mthupi ndipo mwina kuyambitsa zilonda) zomwe sizimayambitsidwa ndi matenda a valavu yamtima. Edoxaban imagwiritsidwanso ntchito kupewetsa mitsempha yakuya kwambiri (DVT; magazi, nthawi zambiri mwendo) ndi kuphatikizika kwamapapu (PE; magazi m'magazi m'mapapu) mwa anthu omwe adalandiridwa ndi mankhwala ojambulidwa ndi magazi a 5 mpaka 10 masiku. Edoxaban ali mgulu la mankhwala otchedwa factor Xa inhibitors. Zimagwira ntchito poletsa kuchitapo kanthu kwachilengedwe komwe kumathandizira kuundana kwamagazi.


Edoxaban imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kapena wopanda chakudya kamodzi patsiku. Tengani edoxaban mozungulira nthawi imodzimodzi tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani edoxaban ndendende monga mwadongosolo Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Ngati mukulephera kumeza mapiritsiwo, aphwanyeni ndi kuwasakaniza ndi ma ola 2 kapena 3 (60 mpaka 90 mL) amadzi kapena maapulosi. Tengani chisakanizo nthawi yomweyo.

Ngati muli ndi chubu cha m'mimba, mapiritsiwo amatha kuphwanyidwa ndikusakanizidwa m'madzi ndikupatsidwa kudzera mu chubu. Funsani dokotala wanu kapena wamankhwala momwe muyenera kumwa mankhwalawa. Tsatirani malangizowa mosamala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge edoxaban,

  • Uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la edoxaban, mankhwala ena aliwonse, kapena chilichonse mwazomwe zimaphatikizidwa ndi mapiritsi a edoxaban. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
  • auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa.Onetsetsani kuti mwatchula mankhwala omwe adalembedwa mgawo la CHENJEZO LOFUNIKA ndi zina mwa izi: amiodarone (Cordarone, Pacerone), atorvastatin (Lipitor, ku Caduet, ku Liptruzet), cyclosporine (Gengraf, Neoral), digoxin (Lanoxin), dronedarone ( Multaq), erythromycin (EES, E-Mycin, Erythrocin), esomeprazole (Nexium, ku Vimovo), ketoconazole (Nizoral), quinidine, rifampin (Rifadin, ku Rifamate, ku Rifater, Rimactane), serotonin-reuptake (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Selfemra), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), ndi sertraline (Zoloft); serotonin-norepinephrine reuptake inhibitors (SNRI) monga desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), milnacipran (Savella), ndi venlafaxine (Effexor); ndi verapamil (Calan, Covera, Isoptin, Verelan, ku Tarka). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi edoxaban, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sawoneka pamndandandawu.
  • Uzani dokotala wanu ngati mukudwala magazi paliponse m'thupi lanu omwe sangathe kuyimitsidwa. Dokotala wanu angakuuzeni kuti musatenge edoxaban.
  • uzani dokotala ngati mukulemera mapaundi 132 (60 kilograms) kapena ochepera ndipo ngati mwakhalapo ndi vuto la kutuluka magazi, valavu yamtima yamakina, antiphospholipid syndrome (matenda omwe amayambitsa magazi omwe amachititsa magazi kuundana), khansa ya m'mimba kapena matumbo, kapena mtima, matenda a impso kapena chiwindi.
  • Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga edoxaban, itanani dokotala wanu.
  • ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa edoxaban.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.


Tengani mlingo womwe mwaphonya mukangokumbukira tsiku lomwelo. Komabe, ngati ndi tsiku lotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Edoxaban ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • zidzolo
  • kutopa kapena kufooka kosazolowereka
  • chizungulire
  • khungu lotumbululuka

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa mgawo LENJEZO LOFUNIKA, lekani kumwa edoxaban ndikuimbira foni nthawi yomweyo:

  • nkhama zotuluka magazi
  • mwazi wa m'mphuno
  • kutuluka magazi kwambiri kumaliseche
  • mkodzo wofiira, pinki, kapena bulauni
  • ofiira kapena akuda, mipando yodikira
  • kutsokomola kapena kusanza magazi kapena zinthu zomwe zimawoneka ngati malo a khofi

Edoxaban ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

  • kutuluka mwachilendo kapena kuphwanya
  • chimbudzi chamagazi, chakuda, kapena chochedwa
  • magazi mkodzo
  • kutsokomola kapena kusanza magazi kapena zinthu zomwe zimawoneka ngati malo a khofi

Musanapite kukayezetsa labotale, auzeni adotolo ndi ogwira nawo ntchito kuti mukumwa edoxaban.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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