Macitentan

Zamkati

• Musanatenge macitentan,
• Macitentan ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, siyani kumwa macitentan ndipo itanani dokotala nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:
• Zizindikiro za bongo zingaphatikizepo:

Kwa odwala achikazi:

Musatenge macitentan ngati muli ndi pakati kapena mukufuna kutenga pakati. Pali chiopsezo chachikulu kuti macitentan ivulaza mwana wosabadwayo.

Chifukwa cha kuopsa koopsa kwa fetus, pulogalamu yotchedwa OPSUMIT Risk Evaluation and Mitigation Strategy (OPSUMIT REMS) yakhazikitsidwa kuti iwonetsetse kuti mayi wapakati satenga macitentan, ndipo mayiyu satenga mimba akumwa macitentan. Azimayi onse, kuphatikiza azimayi omwe sangatenge mimba, amatha kulandira macitentan pokhapokha atalembetsa ndi OPSUMIT REMS, kukhala ndi mankhwala ochokera kwa dokotala yemwe adalembetsa ku OPSUMIT REMS, ndikudzaza mankhwalawo ku pharmacy yomwe imalembetsedwa ndi OPSUMIT CHIKUMBUTSO.

Dokotala wanu adzakulembetsani ku OPSUMIT REMS. Dokotala wanu angakuwuzeni za kuopsa kwa macitentan, makamaka kuopsa kwa zopindika zazikulu zobereka mukamamwa mukakhala ndi pakati. Muyenera kusaina chikalata chovomerezeka cholongosola kuti mumvetsetsa izi kuti dokotala wanu akulembetseni.

Dokotala wanu adzawonetsanso ngati mungathe kutenga pakati. Ngati mwafika msinkhu (pamene thupi la mwana limakhwima mwakuthupi ndikutha kukhala ndi mwana), khalani ndi chiberekero, ndipo simunapitirire kusamba ('kusintha kwa moyo' kumapeto kwa msambo) mumawoneka ngati wamkazi Ndani angathe kutenga pakati, ndipo muyenera kutsatira malamulo ena owonjezera kuti mulandire macitentan.

Kwa akazi omwe amatha kutenga pakati:

Muyenera kugwiritsa ntchito njira yodalirika yothandizira kubadwa nthawi yonse yomwe mumalandira macitentan, komanso kwa mwezi umodzi mutatha kumwa. Dokotala wanu angakuuzeni mitundu yoletsa kuvomerezeka yomwe ingavomerezedwe, ndipo akupatsirani zomwe zalembedwa zakulera. Nthawi zambiri mudzafunika kugwiritsa ntchito njira ziwiri zakulera kuti mupewe kutenga mimba mukamamwa macitentan.

Muyenera kuyezetsa mimba musanayambe mankhwala, mwezi uliwonse mukamalandira chithandizo, komanso mwezi umodzi mutatha kumwa mankhwala omaliza kuti athe kulandira macitentan. Dokotala wanu adzakulemberani mayeso oyembekezera. Sitoloyo siyingakupatseni macitentan mpaka atatsimikizira kuti mwalandira mayeso anu ofunikira.

Simuyenera kugonana mosadziteteza mukamamwa macitentan.

Itanani dokotala wanu nthawi yomweyo ngati mwagonana mosadziteteza, ganizirani kuti kulera kwanu kwalephera, kusowa nthawi yanu, kapena kuganiza kuti mutha kukhala ndi pakati pazifukwa zilizonse. Adzakambirana nanu zosankha zanu zachipatala. Musayembekezere mpaka nthawi yanu yotsatira kudzakambirana izi ndi dokotala wanu.

Uzani dokotala wanu ngati simukumvetsa zonse zomwe munauzidwa zakulera, kapena ngati simukuganiza kuti mutha kugwiritsa ntchito njira zovomerezeka zolerera nthawi zonse mukamalandira chithandizo.

Ngati ndinu kholo kapena wosamalira mkazi yemwe anali asanakule msinkhu, yang'anani mwana wanu pafupipafupi kuti muwone ngati akukula zizindikiro zakusandulika (masamba a m'mawere, tsitsi labanja) ndipo mulole dokotala kuti adziwe zosintha zilizonse.

Kwa odwala onse:

Macitentan sikupezeka m'masitolo ogulitsa. Mankhwala anu adzakutumizirani ku pharmacy yapadera yomwe imalembetsedwa ndi OPSUMIT REMS. Ngati ndinu mkazi amene simunathe msinkhu kapena mkazi amene watha kutenga pakati mudzalandira masiku 30 okha panthawi imodzi. Funsani dokotala wanu ngati muli ndi mafunso okhudza momwe mudzalandire mankhwala anu.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba kulandira mankhwala ndi macitentan ndipo nthawi iliyonse mukamadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Macitentan imagwiritsidwa ntchito kuthana ndi zizindikilo za m'mapapo mwanga (PAH; kuthamanga kwa magazi m'mitsempha yomwe imanyamula magazi kumapapu). Macitentan ali mgulu la mankhwala otchedwa endothelin receptor antagonists. Zimagwira ntchito poletsa endothelin, mankhwala achilengedwe omwe amachititsa kuti mitsempha yamagazi ichepetse komanso kupewa magazi omwe amapezeka mwa anthu omwe ali ndi PAH.

Macitentan amabwera ngati piritsi kuti atenge pakamwa. Nthawi zambiri amatengedwa kapena wopanda chakudya kamodzi patsiku. Tengani macitentan mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani macitentan ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza mapiritsi lonse; osagawana, kutafuna, kapena kuwaphwanya.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge macitentan,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la mankhwala a macitentan, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a macitentan. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala omwe simukulembera, mavitamini, ndi zowonjezera zakudya zomwe mumamwa kapena mukukonzekera. Onetsetsani kuti mwatchulapo izi: carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), clarithromycin (Biaxin, ku Prevpac); efavirenz (Sustiva); ma virus ena a HIV protease monga nelfinavir (Viracept), indinavir (Crixivan), ndi ritonavir (Norvir, ku Kaletra); itraconazole (Onmel, Sporanox); ketoconazole; nefazodone; nevirapine Viramune); phenobarbital; phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); ndi rifampin (Rifadin, Rifamate, Rifater, Rimactane). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi macitentan, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• uzani dokotala wanu ngati mwakhalapo ndi kuchepa kwa magazi m'thupi (momwe maselo ofiira samabweretsa mpweya wokwanira ku ziwalo) kapena matenda a chiwindi.
• osayamwa mukamwa mankhwalawa.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka mwa amuna. Lankhulani ndi dokotala wanu za kuopsa kwakumwa macitentan.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Macitentan ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• mphuno yodzaza
• chikhure
• chifuwa
• chimfine ngati zizindikiro
• mutu
• Kukodza mwachangu, pafupipafupi, kapena kupweteka
• zidzolo

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, siyani kumwa macitentan ndipo itanani dokotala nthawi yomweyo kapena mupeze chithandizo chadzidzidzi:

• khungu loyabwa
• mkodzo wakuda
• chikasu cha khungu lanu kapena maso
• ululu kumtunda chakumanja kwa m'mimba mwanu
• nseru kapena kusanza kosadziwika
• kusowa chilakolako
• kutopa kwambiri
• malungo
• kutupa kwa nkhope, mmero, lilime, milomo, ndi maso
• zovuta kumeza kapena kupuma
• ukali
• kupuma movutikira, makamaka akagona pansi
• kukhosomola pinki, chifuwa chozizira kapena magazi
• kuwonjezeka kwachilendo kulemera
• kutupa kwa akakolo kapena miyendo

Macitentan ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• mutu
• nseru
• kusanza

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amatha kuyitanitsa mayeso kuti muwone momwe chiwindi chanu chikugwirira ntchito, komanso kuti muwone kuchepa kwa magazi musanayambe mankhwala komanso nthawi ndi nthawi mukamalandira macitentan.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Kutsegula^®