Mlembi: Clyde Lopez
Tsiku La Chilengedwe: 23 Kulayi 2021
Sinthani Tsiku: 18 Novembala 2024
Anonim
ALEX: alectinib is the best first-line therapy available for ALK-positive NSCLC
Kanema: ALEX: alectinib is the best first-line therapy available for ALK-positive NSCLC

Zamkati

Alectinib imagwiritsidwa ntchito pochiza mtundu wina wa khansa ya m'mapapo yaing'ono (NSCLC) yomwe yafalikira mbali zina za thupi. Alectinib ali mgulu la mankhwala otchedwa kinase inhibitors. Zimagwira ntchito poletsa proteni yachilendo yomwe imawonetsa kuti ma cell a khansa achulukane. Izi zimathandiza kuchepetsa kapena kuletsa kufalikira kwa maselo a khansa.

Alectinib imabwera ngati kapisozi woti atenge pakamwa. Nthawi zambiri amatengedwa ndi chakudya kawiri patsiku. Tengani alectinib mozungulira nthawi yofananira tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani alectinib ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Kumeza makapisozi lonse; musatsegule kapena kuwataya.

Ngati musanza mutatenga alectinib, musatengere mlingo wina nthawi yomweyo. Pitirizani dongosolo lanu lokhazikika.

Dokotala wanu akhoza kuyimitsa chithandizo chanu kwakanthawi kapena kosatha kapena kuchepetsa mlingo wanu ngati mukukumana ndi zovuta zina za alectinib. Uzani dokotala wanu momwe mukumvera mukamalandira chithandizo. Pitirizani kutenga alectinib ngakhale mutakhala bwino. Osasiya kumwa alectinib osalankhula ndi dokotala.


Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge alectinib,

  • Uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la alectinib, mankhwala ena aliwonse, kapena zosakaniza zilizonse mu makapisozi alectinib. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
  • auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: Mankhwala othandizira kuthamanga kwa magazi kapena mavuto amtima. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
  • Uzani dokotala wanu ngati mwakhalapo ndi matenda a chiwindi, mapapu kapena kupuma, kapena kugunda kwamtima pang'ono kapena kosafunikira.
  • uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati, kapena ngati mukufuna kukhala ndi mwana. Simuyenera kutenga pakati mukatenga alectinib. Ngati ndinu wamkazi, muyenera kugwiritsa ntchito njira yodalirika yolerera mukamamwa alectinib komanso kwa sabata limodzi mutangomaliza kumwa mankhwala. Ngati ndinu wamwamuna, inu ndi mnzanuyo muyenera kugwiritsa ntchito njira yoletsa kuyamwa mukamamwa alectinib komanso kwa miyezi itatu mutatha kumwa. Ngati inu kapena mnzanu mukhala ndi pakati mukatenga alectinib itanani dokotala wanu mwachangu. Alectinib ikhoza kuvulaza mwanayo.
  • uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwitsa mukamamwa alectinib komanso kwa sabata limodzi mutamwa mankhwala omaliza.
  • konzani kupewa kupezeka kwa dzuwa kosafunikira kapena kwakanthawi (kuphatikiza zowunikira ndi mabedi ofufuta) komanso kuvala zovala zoteteza, magalasi a dzuwa, ndi zotchingira dzuwa zomwe zimakhala ndi zoteteza dzuwa (SPF) zosachepera 50 mukamamwa alectinib komanso masiku osachepera 7 mlingo wanu wotsiriza. Alectinib imatha kupangitsa khungu lanu kumvetsetsa kuwala kwa dzuwa.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.


Pitani muyezo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Alectinib ikhoza kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • kudzimbidwa
  • kutsegula m'mimba
  • kutupa m'manja mwanu, nkhope, kapena zikope
  • mutu
  • kunenepa
  • zidzolo

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa mu gawo la MAWONEKEDWE OTHANDIZA, pitani kuchipatala nthawi yomweyo:

  • kupuma kwatsopano kapena kukulira, kupuma movutikira, kapena kutsokomola
  • malungo
  • kupweteka pachifuwa mwadzidzidzi
  • chizungulire, mutu wopepuka, kapena kukomoka
  • masomphenya amasintha
  • kupweteka mwadzidzidzi kwa minofu, kukoma mtima, kapena kufooka
  • kupweteka kwa msana
  • kutopa
  • zidzolo
  • khungu loyabwa
  • kusowa chilakolako
  • nseru
  • kusanza
  • chikasu chachikopa kapena kuyera kwa maso ako
  • kupweteka kumanja kwa gawo m'mimba mwanu
  • sinthani kuchuluka kapena mtundu wa mkodzo wanu
  • kutupa kwatsopano kapena kukulira m'miyendo kapena m'mapazi anu
  • Kutuluka magazi kapena kuphwanya mosavuta kuposa zachilendo

Alectinib ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.


Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisunge kutentha komanso kutali ndi kuwala, kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amayang'ana kugunda kwa mtima kwanu ndi kuthamanga kwa magazi pafupipafupi ndikulamula mayeso ena a labu kuti muwone momwe thupi lanu likuyankhira alectinib.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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