Acidicholic acid

Zamkati

• Musanamwe asidi obeticholic,
• Obeticholic acid amatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu:
• Zizindikiro za bongo zingaphatikizepo izi:

Obeticholic acid imatha kuwononga chiwindi chachikulu kapena chowopsa, makamaka ngati kuchuluka kwa obeticholic acid sikusintha matenda a chiwindi akukulira. Ngati mukukumana ndi izi mwazizindikiro mukamamwa obeticholic acid, itanani dokotala wanu mwachangu: chikaso cha khungu kapena maso, mkodzo wakuda, mipando yakuda, kutsokomola kapena kusanza magazi, nseru, kusanza, kupweteka m'mimba, kutupa mkati ndi mozungulira M'mimba, kuchepa thupi, kusowa njala, kutopa, kutsegula m'mimba, kusokonezeka, kusalankhula bwino, kuda nkhawa, kusintha kwa malingaliro, kusintha umunthu, kapena kukodza pafupipafupi.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amatha kuyitanitsa mayeso ena musanachitike komanso mukamalandira chithandizo kuti muwone momwe chiwindi chanu chikuyendera komanso momwe thupi lanu limayankhira ku obeticholic acid.

Obeticholic acid imagwiritsidwa ntchito yokha kapena kuphatikiza ursodiol (Actigall, Urso) kuchiza biliary cholangitis (PBC; mtundu wa matenda a chiwindi omwe amawononga timitsempha ta ndulu, tomwe timalola kuti ndulu ikhale m'chiwindi ndikuwononga) mwa anthu omwe sangatenge ursodiol kapena mwa anthu omwe sanalandire chithandizo bwino ndi ursodiol okha. Obeticholic acid ali mgulu la mankhwala otchedwa farnesoid X receptor agonists. Zimagwira ntchito pochepetsa kupanga kwa bile m'chiwindi ndikuwonjezera kuchotsedwa kwa ndulu pachiwindi.

Obeticholic acid amabwera ngati piritsi kuti atenge pakamwa. Amatengedwa nthawi zambiri kamodzi kapena tsiku popanda chakudya. Tengani obeticholic acid mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani obeticholic acid ndendende monga momwe akuuzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu angafunikire kuyimitsa chithandizo chanu kwakanthawi kapena kwanthawi zonse kapena muchepetse kuchuluka kwanu kwa obeticholic acid mukamalandira chithandizo. Izi zimadalira momwe mankhwalawa amakuthandizirani kapena ngati mukukumana ndi zovuta zina. Pitirizani kumwa obeticholic acid ngakhale mukumva bwino. Osasiya kumwa obeticholic acid osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanamwe asidi obeticholic,

• uzani dokotala ndi wamankhwala ngati muli ndi vuto la obeticholic acid, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a obeticholic acid. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: caffeine (yomwe imapezeka m'mankhwala ena kuti muzitha kugona ndi kupweteka mutu), theophylline (Elixophyllin, Theo-24, Theochron, ena), tizanidine (Zanaflex), kapena warfarin (Coumadin, Jantoven). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake. Mankhwala ena ambiri amathanso kulumikizana ndi obeticholic acid, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
• ngati mukumwa cholestyramine (Prevalite), colestipol (Colestid), kapena colesevelam (Welchol), imwani osachepera maola 4 isanakwane kapena maola 4 kuchokera ku obeticholic acid.
• uzani dokotala wanu ngati muli ndi zotchinga za bile (kutsekeka m'machubu zomwe zimanyamula bile kuchokera pachiwindi kupita kundulu ndi m'matumbo ang'ono). Dokotala wanu angakuuzeni kuti musamwe obeticholic acid.
• Uzani dokotala wanu ngati mwakhalapo ndi cholesterol kapena matenda amtundu wa chithokomiro.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga obeticholic acid, itanani dokotala wanu.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Obeticholic acid amatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kupweteka pakamwa kapena pakhosi
• kuthamanga, kusasinthasintha, kapena kugunda kwamtima
• zidzolo
• chizungulire
• kukomoka
• kutupa kwa manja, mapazi, akakolo, kapena miyendo yakumunsi
• kutopa kapena kufooka
• kulumikizana kapena kupweteka kwa minofu
• kudzimbidwa

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa MUCHENJEZO CHENJEZO, itanani dokotala wanu mwachangu:

• kuyabwa kwambiri
• malungo, kuzizira, kapena zizindikiro zina za matenda
• kuuma, kuyabwa, kufiira, kupindika kapena ngalande za khungu

Obeticholic acid amatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• chikasu cha khungu kapena maso
• mkodzo wachikuda
• kusowa chilakolako
• kupweteka kumtunda chakumanja kwam'mimba
• nseru
• kusanza
• kutupa m'dera lozungulira mimba

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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