Safinamide

Zamkati

• Musanatenge safinamide,
• Safinamide angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

Safinamide imagwiritsidwa ntchito limodzi ndi levodopa ndi carbidopa (Duopa, Rytary, Sinemet, ena) kuti athetse magawo `` oletsa '' (nthawi zovuta kusuntha, kuyenda, ndikuyankhula zomwe zitha kuchitika ngati mankhwala akutha kapena mwachisawawa) mu anthu omwe ali ndi matenda a Parkinson (PD; vuto lamanjenje lomwe limayambitsa zovuta poyenda, kuwongolera minofu, ndikuwongolera). Safinamide ali mgulu la mankhwala otchedwa monoamine oxidase type B (MAO-B) inhibitors. Zimagwira ndikuwonjezera kuchuluka kwa dopamine (chinthu chachilengedwe chomwe chimafunikira kuwongolera mayendedwe) muubongo.

Safinamide amabwera ngati piritsi kuti atenge pakamwa. Nthawi zambiri amatengedwa popanda chakudya kamodzi patsiku. Tengani safinamide mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani safinamide monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu angayambe ndi mlingo wochepa wa safinamide ndipo akhoza kuwonjezera mlingo wanu kamodzi pakatha milungu iwiri yothandizidwa.

Osasiya kumwa safinamide osalankhula ndi dokotala. Dokotala wanu akhoza kuchepetsa mlingo wanu musanaime. Mukasiya mwadzidzidzi kumwa safinamide, mutha kukhala ndi zizindikilo zobwerera m'thupi monga malungo; kuuma kwa minofu; chisokonezo; kapena kusintha kwa chidziwitso. Uzani dokotala wanu ngati mukukumana ndi zina mwazizindikirozi mukamachepetsa safinamide.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge safinamide,

• Uzani dokotala ndi wazamankhwala ngati muli ndi vuto la safinamide (kutupa pakamwa kapena lilime, kupuma movutikira), mankhwala ena aliwonse, kapena zina zilizonse m'mapiritsi a safinamide. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• uzani dokotala wanu ngati mukumwa izi: amphetamines (zolimbikitsa, 'upper') monga amphetamine (Adderall, Adzenys, Dyanavel XR, ku Adderall), dextroamphetamine (Dexedrine, ku Adderall), ndi methamphetamine (Desoxyn); mankhwala ena opondereza monga amitriptyline (Elavil), amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Tofranil), mirtazapine (Remeron) ndi trazodone; busipulo; cyclobenzaprine (Amrix); methylphenidate (Aptensio, Metadate, Ritalin, ena); ma opioid monga meperidine (Demerol), methadone (Dolophine, Methadose), propoxyphene (sichikupezeka ku US; Darvon), kapena tramadol (Conzip, Ultram, mu Ultracet); serotonin ndi norepinephrine reuptake inhibitors (SSNRIs) monga duloxetine (Cymbalta) ndi venlafaxine (Effexor); ndi wort wa St. Komanso muuzeni dokotala ngati mukumwa MAO inhibitor monga isocarboxazid (Marplan), linezolid (Zyvox), methylene buluu, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), kapena tranylcypromine (Parnate) kapena mwasiya kumwa iwo mkati mwa masabata awiri apitawa. Dokotala wanu angakuuzeni kuti simuyenera kumwa safinamide pamodzi ndi mankhwala aliwonsewa. Mukasiya kumwa safinamide, muyenera kudikirira masiku osachepera 14 musanamwe mankhwalawa. Komanso, musatenge dextromethorphan (mu Robitussin DM; yomwe imapezeka m'mafupa ambiri osalembetsedwa ndi mankhwala ozizira) pamodzi ndi safinamide.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: ma antipsychotic monga clozapine (Clozaril, Fazaclo, Versacloz) ndi olanzapine (Zyprexa); benzodiazepines monga alprazolam (Xanax), diazepam (Diastat, Valium), lorazepam (Ativan), temazepam (Restoril), ndi triazolam (Halcion); mankhwala a chimfine ndi chifuwa (decongestant) kuphatikiza omwe adayikidwa m'diso kapena mphuno; imatinib (Gleevec); irinotecan (Camptosar, Onivyde); isoniazid (Laniazid, ku Rifamate, ku Rifater); lapatinib (Tykerb); methotrexate (Otrexup, Rasuvo); metoclopramide (Reglan); mitochantrone; rosuvastatin (Crestor); serotonin reuptake inhibitors monga citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax, ena), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), ndi sertraline (Zoloft); sulfasalazine (Azulfidine); ndi topotecan (Hycamtin). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• uzani dokotala wanu ngati muli ndi matenda a chiwindi. Dokotala wanu angakuuzeni kuti musatenge safinamide.
• Uzani dokotala wanu ngati mwakhalapo kapena mudakhalapo ndi matenda amisala monga schizophrenia (matenda amisala omwe amachititsa kusokonezeka kwamaganizidwe, kusowa chidwi pamoyo, komanso kukhudzika kapena zachilendo), kusinthasintha kwa malingaliro (kusinthasintha kwamalingaliro kumasintha kukhala osangalala modabwitsa) , kapena matenda amisala; kapena ngati muli ndi kuthamanga kwa magazi kapena kuthamanga magazi; dyskinesia (mayendedwe achilendo); kapena mavuto ogona. Uzaninso dokotala wanu ngati inu kapena wachibale wanu mwakhala mukukumana ndi mavuto ndi diso la maso anu kapena maalubino (mkhalidwe wobadwa nawo womwe umayambitsa kusowa kwa khungu pakhungu, tsitsi ndi maso).
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Mukakhala ndi pakati mukatenga safinamide, itanani dokotala wanu.
• uzani dokotala wanu ngati mukuyamwitsa kapena mukufuna kuyamwitsa.
• muyenera kudziwa kuti safinamide imatha kukupangitsani kugona kapena itha kukupangitsani kugona modzidzimutsa mukamagwira ntchito tsiku ndi tsiku. Mwina simungamve kugona kapena kukhala ndi zizindikiro zina musanagone mwadzidzidzi.Osayendetsa galimoto, kugwiritsa ntchito makina, kugwira ntchito pamalo okwera, kapena kuchita nawo zoopsa pachiyambi cha chithandizo chanu mpaka mutadziwa momwe mankhwalawo amakukhudzirani. Ngati mumagona modzidzimutsa pamene mukuchita zinthu monga kuonera TV, kulankhula, kudya, kapena kukwera galimoto, kapena ngati mutagona kwambiri, makamaka masana, itanani dokotala wanu. Osayendetsa, kugwira ntchito m'malo okwezeka, kapena kugwiritsa ntchito makina mpaka mutalankhula ndi dokotala wanu.
• kumbukirani kuti mowa umatha kuwonjezera ku tulo chifukwa cha mankhwalawa. Musamamwe mowa mukamamwa safinamide.
• Muyenera kudziwa kuti anthu ena omwe amamwa mankhwala monga safinamide adayamba kukhala ndi vuto la kutchova juga kapena zolakalaka zina kapena zikhalidwe zina zomwe zinali zowakakamiza kapena zachilendo kwa iwo, monga zolakalaka zakugonana kapena zikhalidwe. Itanani dokotala wanu ngati muli ndi chidwi chofuna kutchova juga komwe kuli kovuta kuletsa, muli ndi chidwi chachikulu, kapena simutha kudziletsa. Uzani achibale anu za chiopsezo ichi kuti athe kuyimbira adokotala ngakhale simukuzindikira kuti kutchova juga kwanu kapena zina zilizonse zolimbikitsa kapena zikhalidwe zina zasanduka vuto.

Mutha kukhala ndi vuto lalikulu mukamadya zakudya zomwe zili ndi tyramine wochuluka mukamamwa mankhwala a safinamide. Tyramine imapezeka mu zakudya ndi zakumwa zambiri, kuphatikiza nyama, nkhuku, nsomba, kapena tchizi zomwe zasuta, kukalamba, kusungidwa molakwika, kapena kuwonongeka; zipatso, ndiwo zamasamba, ndi nyemba; zakumwa zoledzeretsa; ndi zopangira yisiti zofufumitsa. Dokotala wanu kapena wazakudya zakuwuzani zakudya zomwe muyenera kupewa kwathunthu, ndi zakudya zomwe mungadye pang'ono. Ngati mumadya chakudya chomwe chili ndi tyramine yambiri mukamamwa safinamide, funsani dokotala wanu.

Pitani muyezo womwe mwaphonya ndikumwa mlingo wanu wotsatira nthawi yotsatira tsiku lotsatira. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Safinamide angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kuvuta kugona kapena kugona

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• kukulirakulira kapena kusuntha kwakanthawi kwamthupi komwe simungathe kuwongolera
• masomphenya amasintha
• kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe)
• zikhulupiriro zabodza (kukhulupirira zinthu zosakhala zenizeni)
• kusokonezeka, kuyerekezera zinthu m'maganizo, kuyerekezera thupi, kutentha thupi, thukuta, chisokonezo, kugunda kwa mtima, kunjenjemera, kuuma kwambiri kwa minofu kapena kugwedezeka, kutayika kwa mgwirizano, nseru, kusanza, kapena kutsekula m'mimba

Safinamide imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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