Jekeseni wa Durvalumab

Zamkati

• Musanalandire jekeseni wa durvalumab,
• Jekeseni wa Durvalumab itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

Durvalumab imagwiritsidwa ntchito pochiza khansa ya m'mapapo yaing'ono kwambiri (NSCLC) yomwe imafalikira kumatenda oyandikira ndipo sangathe kuchotsedwa ndi opaleshoni koma sinavutike atalandira mankhwala ena a chemotherapy ndi mankhwala a radiation. Jekeseni wa Durvalumab imagwiritsidwanso ntchito limodzi ndi etoposide (Etopophos) komanso carboplatin kapena cisplatin yochizira khansa yaying'ono yaying'ono yamapapo (ES-SCLC) mwa akulu omwe khansa yawo yafalikira m'mapapu ndi mbali zina za thupi. Jekeseni ya Durvalumab ili mgulu la mankhwala otchedwa monoclonal antibodies. Zimagwira ntchito pothandiza chitetezo cha mthupi chanu kuti muchepetse kapena kuletsa kukula kwa maselo a khansa.

Jakisoni wa Durvalumab amabwera ngati madzi oti alowe mumtsinje kwa mphindi 60 ndi dokotala kapena namwino kuchipatala kapena kuchipatala. Pochiza khansa ya m'mitsempha kapena NSCLC, nthawi zambiri imaperekedwa kamodzi pamasabata awiri malinga ngati dokotala akuuzani kuti mulandire chithandizo kapena NSCLC mpaka chaka chimodzi. Pochiza ES-SCLC, nthawi zambiri imaperekedwa kamodzi pamasabata atatu pamiyendo inayi ndi mankhwala ena, kenako kamodzi pamasabata anayi bola dokotala akuuzani kuti mulandire chithandizo.

Jekeseni wa Durvalumab imatha kuyambitsa mavuto akulu kapena owopseza moyo pakulowetsedwa. Dokotala kapena namwino adzakuyang'anirani mosamala mukamakulowetsedwako ndipo posakhalitsa kulowetsedwa kuti awonetsetse kuti simukuyankha bwino mankhwalawo. Uzani dokotala wanu kapena namwino nthawi yomweyo ngati mungakhale ndi izi: Zizindikiro kapena kugwedezeka, kuyabwa, kuthamanga, kuthamanga, kupuma movutikira, chizungulire, malungo, kukomoka, kupweteka kwa msana kapena khosi, kapena kutupa ya nkhope yanu.

Dokotala wanu akhoza kuchepetsa kulowetsedwa kwanu, kuchedwetsa kapena kuyimitsa chithandizo chanu ndi jekeseni wa durvalumab, kapena kukupatsani mankhwala owonjezera kutengera kuyankha kwanu kwa mankhwalawo ndi zovuta zina zomwe mungakumane nazo. Lankhulani ndi dokotala wanu za momwe mukumvera mukamalandira chithandizo.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Chithandizo cha Mankhwala) mukayamba chithandizo ndi jekeseni wa durvalumab ndipo nthawi iliyonse yomwe mumalandira mankhwala. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kapena tsamba laopanga kuti mupeze Medication Guide.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanalandire jekeseni wa durvalumab,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la durvalumab, mankhwala ena aliwonse, kapena zosakaniza zilizonse za jekeseni wa durvalumab. Funsani wamankhwala wanu kapena onani Chithandizo cha Mankhwala kuti mupeze mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni adotolo ngati mudadulidwapo. Muuzeni dokotala wanu ngati mwakhalapo ndi matenda omwe amadzichotsera okha (momwe chitetezo cha mthupi chimagwirira gawo labwino la thupi) monga matenda a Crohn's (momwe chitetezo cha mthupi chimagwirira ntchito m'mimba momwe zimapwetekera, Kutsekula m'mimba, kuchepa thupi, ndi malungo), ulcerative colitis (vuto lomwe limayambitsa kutupa ndi zilonda m'mbali mwa kholingo [matumbo akulu] ndi rectum), kapena lupus (momwe chitetezo cha mthupi chimagwilira ziphuphu ndi ziwalo zambiri kuphatikiza khungu, mafupa, magazi, ndi impso); mtundu uliwonse wamatenda am'mapapo kapena kupuma; kapena matenda a chiwindi. Komanso muuzeni dokotala ngati mukumalandira chithandizo cha matenda.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Simuyenera kutenga pakati mukalandila jekeseni wa durvalumab. Muyenera kugwiritsa ntchito njira yolerera yothandiza kupewa mimba mukamalandira jakisoni wa durvalumab komanso kwa miyezi itatu mutatha kumwa. Lankhulani ndi dokotala wanu za njira zolerera zomwe zingakuthandizeni. Mukakhala ndi pakati mukalandira durvalumab jekeseni, itanani dokotala wanu mwachangu. Jekeseni wa Durvalumab itha kuvulaza mwana wosabadwayo.
• auzeni dokotala ngati mukuyamwitsa kapena mukufuna kuyamwitsa. Simuyenera kuyamwa mukalandira durvalumab jakisoni komanso kwa miyezi itatu mutatha kumwa mankhwala.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Jekeseni wa Durvalumab itha kuyambitsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kupweteka kwa mafupa kapena minofu
• kutupa kwa mikono kapena miyendo yanu
• kudzimbidwa

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

• chifuwa chatsopano kapena chowonjezereka, kupweteka pachifuwa, kapena kupuma pang'ono
• chikasu cha maso kapena khungu lako, kutuluka magazi kapena kuvulala mosavuta, kuchepa kwa njala, mkodzo wamdima (wamtundu wa tiyi), kupweteka kumtunda kwakumimba, kutopa kwambiri, nseru kapena kusanza
• kutsekula m'mimba, kupweteka m'mimba, kapena wakuda, wodikira, womata kapena wamagazi
• kuchepa pokodza, magazi mumkodzo, kutupa m'mapazi anu, kuchepa kwa njala
• malungo, chifuwa, kuzizira, chimfine ngati zizindikilo, kukodza pafupipafupi kapena kupweteka, kapena zizindikilo zina za matenda
• kupweteka mutu komwe sikudzatha kapena kupweteka kwachilendo; kutopa kwambiri; kuonda kapena phindu; kuchuluka kwa njala kapena ludzu; kumva chizungulire kapena kukomoka; kumva kuzizira, kuzama kwa mawu, kapena kudzimbidwa; kutayika tsitsi; Kusintha kwakusintha kwamakhalidwe ndi machitidwe monga kutsika kwa chilakolako chogonana, kukwiya, kusokonezeka, kapena kuiwala; nseru kapena kusanza; kupweteka m'mimba
• zidzolo, kuyabwa, kapena kuphulika kwa khungu
• kuuma khosi
• kusawona bwino kapena masomphenya awiri, kapena zovuta zina zamasomphenya
• kufiira kwa diso kapena kupweteka

Jekeseni wa Durvalumab imatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone kuyankha kwa thupi lanu ku jakisoni wa durvalumab.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Imfinzi^®