Mlembi: Janice Evans
Tsiku La Chilengedwe: 26 Kulayi 2021
Sinthani Tsiku: 19 Novembala 2024
Anonim
GENVOYA® (elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide) Mechanism of Action
Kanema: GENVOYA® (elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide) Mechanism of Action

Zamkati

Elvitegravir, cobicistat, emtricitabine, ndi tenofovir siziyenera kugwiritsidwa ntchito pochiza matenda a chiwindi a hepatitis B (HBV; matenda opitilira chiwindi). Uzani dokotala wanu ngati muli ndi HBV kapena mukuganiza kuti mwina muli ndi HBV. Dokotala wanu akhoza kukuyesani kuti muone ngati muli ndi HBV musanayambe kumwa mankhwala ndi elvitegravir, cobicistat, emtricitabine, ndi tenofovir. Ngati muli ndi HBV ndipo mumamwa elvitegravir, cobicistat, emtricitabine, ndi tenofovir, matenda anu akhoza kukulirakirani mwadzidzidzi mukasiya kumwa mankhwalawa. Dokotala wanu adzakufunsani ndikuyitanitsa mayeso a labu pafupipafupi kwa miyezi ingapo mutasiya kumwa mankhwalawa kuti muwone ngati HBV yanu yaipiraipira.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu adzaitanitsa mayeso ena musanachitike komanso mukamalandira chithandizo kuti muwone momwe thupi lanu likuyankhira ku elvitegravir, cobicistat, emtricitabine, ndi tenofovir.

Lankhulani ndi dokotala wanu za kuopsa kotenga elvitegravir, cobicistat, emtricitabine, ndi tenofovir.

Kuphatikiza kwa elvitegravir, cobicistat, emtricitabine, ndi tenofovir (Genvoya, Stribilid) amagwiritsidwa ntchito kuchiza matenda opatsirana pogonana a HIV mwa achikulire ndi ana omwe sanalandire mankhwala ena a HIV kapena m'malo mwa mankhwala omwe alipo pakadali pano mwa anthu ena kale kumwa mankhwala a HIV. Kuphatikiza kwa elvitegravir, cobicistat, emtricitabine, ndi tenofovir ali mgulu la mankhwala otchedwa antivirals. Ntchito ya Elvitegravir, emtricitabine, ndi tenofovir pochepetsa kuchuluka kwa kachilombo ka HIV m'magazi. Cobicistat imathandizira kusunga elvitegravir m'thupi nthawi yayitali kuti mankhwala azikhala ndi mphamvu yayikulu. Ngakhale kuphatikiza kwa elvitegravir, cobicistat, emtricitabine ndi tenofovir sikungachiritse HIV, mankhwalawa amachepetsa mwayi wanu wopeza matenda a immunodeficiency (AIDS) ndi matenda okhudzana ndi HIV monga matenda akulu kapena khansa. Kumwa mankhwalawa pamodzi ndi kugonana mosatekeseka ndikusintha zina pamoyo wanu kumachepetsa chiopsezo chotenga kachirombo ka HIV kwa anthu ena.


Kuphatikiza kwa elvitegravir, cobicistat, emtricitabine, ndi tenofovir kumabwera ngati piritsi kuti mutenge pakamwa. Nthawi zambiri amatengedwa ndi chakudya kamodzi patsiku. Tengani elvitegravir, cobicistat, emtricitabine, ndi tenofovir mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani elvitegravir, cobicistat, emtricitabine, ndi tenofovir ndendende monga mwalamulira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Elvitegravir, cobicistat, emtricitabine, ndi tenofovir amathandizira kupewa kachilombo ka HIV koma samachiritsa. Pitilizani kumwa elvitegravir, cobicistat, emtricitabine, ndi tenofovir ngakhale mukumva bwino. Osasiya kumwa elvitegravir, cobicistat, emtricitabine, ndi tenofovir osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.


Musanatenge elvitegravir, cobicistat, emtricitabine, ndi tenofovir,

  • uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la elvitegravir, cobicistat, emtricitabine, kapena tenofovir, mankhwala ena aliwonse, kapena chilichonse chosakaniza mu elvitegravir, cobicistat, emtricitabine, ndi mapiritsi a tenofovir. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
  • Uzani dokotala ngati mukumwa mankhwala aliwonse awa: alfuzosin (Uroxatral); carbamazepine (Carbatrol, Epitol, Tegretol, ena), cisapride (Propulsid) (sikupezeka ku U.S.); mankhwala a ergot monga dihydroergotamine (DHE 45, Migranal), ergotamine (Ergomar, ku Cafergot, ku Migergot), ndi methylergonovine (Methergine); lomitapide (Wowonjezera); lovastatin (Altoprev); lurasidone (Latuda); midazolam (Ndime) pakamwa; phenobarbital; phenytoin (Dilantin, Phenytek); pimozide (Orap); rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater); Chingwe cha St. sildenafil (kokha Revatio, mtundu womwe umagwiritsidwa ntchito matenda am'mapapo); simvastatin (Simcor, Zocor, ku Vytorin); kapena triazolam (Halcion). Dokotala wanu angakuuzeni kuti musatenge elvitegravir, cobicistat, emtricitabine, ndi tenofovir ngati mukumwa mankhwala amodzi kapena angapo.
  • auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: aminoglycoside maantibayotiki monga gentamicin; anticoagulants ('blood thinners') monga apixaban (Eliquis), mafutaxaban (Bevyxxa), dabigatran (Pradaxa), edoxaban (Savaysa), rivaroxaban powder (Xarelto), ndi warfarin (Coumadin, Jantoven); mankhwala antifungal monga itraconazole (Onmel, Sporanox), ketoconazole, ndi voriconazole (Vfend); mankhwala ophera mavairasi monga acyclovir (Sitavig, Zovirax), cidofovir, ganciclovir (Cytovene), valacyclovir (Valtrex), ndi valganciclovir (Valcyte); aspirin ndi mankhwala ena osagwiritsa ntchito kutupa (NSAIDs) monga ibuprofen (Advil, Motrin) ndi naproxen (Aleve, Naprosyn); atorvastatin (Lipitor, mu Caduet); benzodiazepines monga clonazepam (Klonopin), clorazepate (Gen-Xene, Tranxene), diazepam (Diastat, Valium), estazolam, flurazepam, ndi midazolam amapatsidwa kudzera m'mitsempha (mumtsempha); zotchinga beta monga metoprolol (Lopressor, Toprol-XL, ku Dutoprol) ndi timolol; chifuwa (Tracleer); buprenorphine ndi naloxone (Bunavail, Suboxone); busipulo; calcium blockers monga amlodipine (Norvasc), diltiazem (Cardizem, Diltzac, Tiazac, ena), felodipine, nicardipine (Cardene), nifedipine (Adalat CC, Afeditab CR, Procardia), ndi verapamil (Calan, Verelan, ku Tarka); clarithromycin (Biaxin, mu PrevPac); colchicine (Colcrys, Mitagare, mu Col-Probenecid); dexamethasone; ethosuximide (Zarontin), njira zolerera za mahomoni (mapiritsi oletsa kubala, chigamba, mphete ya nyini, kapena jakisoni); mankhwala a kukhumudwa monga amitriptyline, bupropion (Aplenzin, Forfivo XL, Wellbutrin, Zyban), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Brisdelle, Paxil, Pexeva), ndi trazodone; Mankhwala ena a HIV kapena Edzi kuphatikiza cobicistat (Tybost, ku Evotaz, ku Prezcobix), emtricitabine (Emtriva, ku Atripla, ku Complera, ku Truvada), lamivudine (Epivir, ku Combivir, ku Epzicom, ku Trizivir, ena), ritonavir ( Norvir, ku Kaletra, ku Technivie), ndi tenofovir (Viread, ku Atripla, ku Complera, ku Truvada); fentanyl (Actiq, Duragesic, Subsys); mankhwala a kugunda kwamtima mosasinthasintha monga amiodarone (Nexterone, Pacerone), digoxin (Lanoxin), disopyramide (Norpace), flecainide, lidocaine (Xylocaine), mexiletine, propafenone (Rythmol), ndi quinidine (ku Nuedexta); mankhwala omwe amaletsa chitetezo cha mthupi monga cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), ndi tacrolimus (Prograf); naloxone (Evzio, Narcan); oxcarbazepine (Oxtellar XR, Trileptal); perphenazine; quetiapine (Seroquel); phosphodiesterase (PDE5) inhibitors monga sildenafil (Viagra), tadalafil (Adcirca, Cialis), ndi vardenafil (Levitra, Staxyn); rifabutin (Mycobutin); rifapentine (Priftin); risperidone (Risperdal); salmeterol (Serevent, ku Advair); Steroids yapakamwa kapena inhaled monga betamethasone, budesonide (Pulmicort), ciclesonide (Alvesco, Omnaris), dexamethasone, fluticasone (Flonase, Flovent, ku Advair), methylprednisolone (Medrol). mometasone (ku Dulera). prednisone (Rayos), ndi triamcinolone; telithromycin (Ketek; sakupezeka ku US); thioridazine; tramadol; ndi zolpidem (Ambien, Edluar, Intermezzo, Zolpimist). Mankhwala ena ambiri amathanso kulumikizana ndi elvitegravir, cobicistat, emtricitabine, ndi tenofovir, chifukwa chake onetsetsani kuti muwauze adotolo zamankhwala onse omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
  • ngati mukumwa maantacid okhala ndi aluminium, magnesium, kapena calcium (Maalox, Mylanta, ena), tengani maola 2 isanakwane kapena maola awiri kuchokera elvitegravir, cobicistat, emtricitabine, ndi tenofovir.
  • uzani dokotala wanu ngati mwakhalapo ndi zikhalidwe zotchulidwa mu gawo LOFUNIKITSA CHENJEZO, mavuto a mafupa kuphatikizapo kufooka kwa mafupa (vuto lomwe mafupa amafooka ndi kufooka ndikuthyoka mosavuta) kapena mafupa amtundu uliwonse, matenda amtundu uliwonse omwe samapita kutali kapena komwe kumabwera ndikudutsa monga chifuwa chachikulu (TB; mtundu wamatenda am'mapapo) kapena cytomegalovirus (CMV; matenda opatsirana omwe angayambitse zizindikiro kwa odwala omwe ali ndi chitetezo chamthupi chofooka), kapena matenda a chiwindi kapena impso.
  • Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga elvitegravir, cobicistat, emtricitabine, ndi tenofovir, itanani dokotala wanu nthawi yomweyo. Simuyenera kuyamwa ngati muli ndi kachilombo ka HIV kapena ngati mukumwa elvitegravir, cobicistat, emtricitabine ndi tenofovir.
  • muyenera kudziwa kuti pamene mukumwa mankhwala ochizira kachilombo ka HIV, chitetezo chanu cha mthupi chingakhale champhamvu ndikuyamba kulimbana ndi matenda ena omwe anali kale mthupi lanu. Izi zitha kukupangitsani kukhala ndi zizindikilo za matendawa. Ngati muli ndi zizindikiro zatsopano kapena zowonjezereka mukamamwa mankhwala a elvitegravir, cobicistat, emtricitabine, ndi tenofovir, onetsetsani kuti mwauza dokotala.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.


Tengani mlingo wosowa mukangokumbukira ndi chakudya. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Elvitegravir, cobicistat, emtricitabine, ndi tenofovir zitha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • mutu
  • kuvuta kugona kapena kugona
  • maloto achilendo
  • kutsegula m'mimba
  • mpweya
  • zidzolo

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi chimodzi mwazizindikirozi kapena zomwe zalembedwa m'magulu OTHANDIZA KUCHENJEZA KAPENA KUDZIPEREKA KWAMBIRI, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

  • kutupa kwa nkhope, mmero, lilime, milomo, maso, manja, mapazi, akakolo, kapena miyendo yakumunsi
  • ukali
  • zovuta kumeza kapena kupuma
  • kuchepa pokodza
  • kupweteka m'manja, manja, mapazi, kapena miyendo
  • kupweteka kumtunda chakumanja kwa m'mimba mwanu
  • kusowa chilakolako
  • zizindikiro ngati chimfine
  • nseru
  • kusanza
  • kutopa kwambiri
  • kutuluka mwachilendo kapena kuphwanya
  • kufooka
  • chizungulire
  • wamisala
  • kuthamanga kapena kusakhazikika kwamtima
  • kuvuta kupuma
  • mkodzo wachikasu kapena wabulauni
  • matumbo ofiira owala
  • chikasu cha khungu kapena maso
  • kumva kuzizira, makamaka m'manja kapena m'miyendo
  • kupweteka kwa minofu

Elvitegravir, cobicistat, emtricitabine, ndi tenofovir zimatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Sungani ma elvitegravir, cobicistat, emtricitabine, ndi tenofovir pafupi. Musayembekezere mpaka mutatsala pang'ono kumwa mankhwala kuti mudzaze mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

  • Genvoya® (yokhala ndi Cobicistat, Elvitegravir, Emtricitabine, Tenofovir)
  • Kugulitsa® (yokhala ndi Cobicistat, Elvitegravir, Emtricitabine, Tenofovir)
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