Glecaprevir ndi Pibrentasvir

Zamkati

• Musanatenge glecaprevir ndi pibrentasvir,
• Glecaprevir ndi pibrentasvir zitha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Glecaprevir ndi pibrentasvir zimatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mutha kukhala ndi kachilombo ka hepatitis B (kachilombo kamene kamagwira chiwindi ndipo kakhoza kuwononga chiwindi kwambiri) koma osakhala ndi zisonyezo za matendawa. Poterepa, kutenga kuphatikiza kwa glecaprevir ndi pibrentasvir kumatha kuwonjezera chiopsezo kuti matenda anu akhoza kukhala owopsa kapena owopseza moyo ndipo mudzakhala ndi zizindikiro. Uzani dokotala wanu ngati mwakhalapo ndi kachilombo ka hepatitis B. Dokotala wanu amalamula kuti ayesedwe magazi kuti awone ngati mwadwalapo matenda a hepatitis B. Dokotala wanu adzakuyang'anirani ngati muli ndi matenda a chiwindi cha B mkati ndi miyezi ingapo mutalandira chithandizo. Ngati ndi kotheka, dokotala wanu akhoza kukupatsani mankhwala ochizira matendawa musanachitike komanso mukamamwa mankhwalawa kuphatikiza ndi glecaprevir ndi pibrentasvir. Ngati mukumane ndi zizindikiro izi mukamalandira chithandizo kapena mutalandira chithandizo, itanani dokotala wanu mwachangu: kutopa kwambiri, khungu lachikaso kapena maso, kusowa kwa njala, nseru, kusanza, mipando yotuwa, kupweteka kumtunda chakumanja kwa m'mimba, kapena mkodzo wakuda.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amatha kuyitanitsa mayeso ena asanadye, nthawi, komanso mutalandira chithandizo kuti muwone momwe thupi lanu likuyankhira pophatikizana ndi glecaprevir ndi pibrentasvir.

Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito glecaprevir ndi pibrentasvir.

Kuphatikiza kwa glecaprevir ndi pibrentasvir amagwiritsidwa ntchito pochiza mitundu ina yamatenda (a nthawi yayitali) a chiwindi cha hepatitis C (kutupa kwa chiwindi choyambitsidwa ndi kachilombo) mwa akulu ndi ana azaka 12 kapena kupitilira apo omwe amalemera mapaundi 99 (45) makilogalamu). Amagwiritsidwanso ntchito pochiza mitundu ina yamatenda amtundu wa hepatitis C mwa akulu ndi ana azaka 12 kapena kupitilira apo omwe amalemera pafupifupi mapaundi 99 (45 kilograms) omwe alandila kale mankhwala ena ochizira matenda awo a hepatitis C. Glecaprevir ali mgulu la mankhwala otchedwa HCV NS3 / 4A protease inhibitors. Zimagwira ntchito pochepetsa kuchuluka kwa kachilombo ka hepatitis C (HCV) mthupi. Pibrentasvir ali mgulu la mankhwala otchedwa HCV NS5A inhibitors. Zimagwira ntchito poletsa kachilombo kamene kamayambitsa matenda a hepatitis C kufalikira m'thupi.

Kuphatikiza kwa glecaprevir ndi pibrentasvir kumabwera ngati piritsi kuti mutenge pakamwa. Nthawi zambiri amatengedwa ndi chakudya kamodzi tsiku lililonse kwa masabata 8 mpaka 16. Tengani glecaprevir ndi pibrentasvir mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani glecaprevir ndi pibrentasvir ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Pitirizani kumwa glecaprevir ndi pibrentasvir ngakhale mukumva bwino. Kutalika kwa chithandizo chanu kumadalira momwe mulili, ngati mudamwa mankhwala ena a HCV, momwe mumayankhira mankhwalawo, komanso ngati mukukumana ndi zovuta zina. Osasiya kumwa glecaprevir ndi pibrentasvir osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge glecaprevir ndi pibrentasvir,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la glecaprevir, pibrentasvir, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a glecaprevir ndi pibrentasvir. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• uzani dokotala wanu ngati mukumwa atazanavir (Reyataz, ku Evotaz) kapena rifampin (Rifadin, Rimactane, ku Rifamate, ku Rifater). Dokotala wanu angakuuzeni kuti musamwe glecaprevir ndi pibrentasvir ngati mukumwa imodzi mwa mankhwalawa.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: maanticoagulants ('opopera magazi') monga warfarin (Coumadin, Jantoven); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), mankhwala ochepetsa mafuta m'thupi (ma statins) monga atorvastatin (Lipitor, ku Caduet), fluvastatin (Lescol), lovastatin (Altoprev), pitavastatin (Livalo), pravastatin (Pravachol), rosuvastol Crestor), ndi simvastatin (Zocor, ku Simcor, ku Vytorin); cyclosporine (Gengraf, Neoral, Sandimmune); dabigatran (Pradaxa); digoxin (Lanoxin); ethinyl estradiol njira zolerera zamkamwa monga zina ('mapiritsi oletsa kubereka'), zigamba, mphete za nyini, ndi zinthu zina za ethinyl estradiol; mankhwala ena obwezeretsa mahomoni (HRT); ndi mankhwala ena a kachirombo ka HIV (HIV) kapena matenda a immunodeficiency (AIDS) kuphatikiza darunavir (Prezista, ku Prezcobix), efavirenz (Sustiva, ku Atripla), lopinavir (ku Kaletra), kapena ritonavir (Norvir, ku Kaletra); ndi phenytoin (Dilantin, Phenytek). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• uzani dokotala wanu za mankhwala azitsamba omwe mukumwa, makamaka wort ya St.
• auzeni adotolo ngati muli ndi matenda amtundu wina uliwonse wa chiwindi kupatula hepatitis C. Dokotala wanu akhoza kukuwuzani kuti musatenge glecaprevir ndi pibrentasvir.
• auzeni adotolo ngati mudakhalapo ndi kachilombo ka HIV kapena matenda a shuga, kapena ngati mudalandilapo chiwindi kapena impso.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga glecaprevir ndi pibrentasvir, itanani dokotala wanu.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ngati mwangotsala ndi maola 18 kapena kuchepera pomwe mwaphonya glecaprevir ndi pibrentasvir, imwani mlingo wa chakudya ndi chakudya mukangokumbukira. Komabe, ngati papitilira maola 18 kuyambira nthawi yomwe mumayenera kumwa mankhwala anu, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Glecaprevir ndi pibrentasvir zitha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• mutu
• kutopa
• kufooka
• nseru
• kutsegula m'mimba
• kuyabwa

Glecaprevir ndi pibrentasvir zimatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

• kugona
• chisokonezo
• kutupa kwa m'mimba
• kusanza magazi kapena zinthu zomwe zimawoneka ngati malo a khofi
• mdima wakuda, wakuda, kapena wamagazi

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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