Dacomitinib

Zamkati

• Musanatenge dacomitinib,
• Dacomitinib itha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

Dacomitinib imagwiritsidwa ntchito pochiza khansa yam'mapapo yam'magazi (NSCLC) yomwe yafalikira mbali zina za thupi. Dacomitinib ali mgulu la mankhwala otchedwa kinase inhibitors. Zimagwira ntchito poletsa proteni yachilendo yomwe imawonetsa kuti ma cell a khansa achulukane. Izi zimathandiza kuchepetsa kapena kuletsa kufalikira kwa maselo a khansa.

Dacomitinib imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kamodzi tsiku lililonse kapena wopanda chakudya. Tengani dacomitinib mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani dacomitinib ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Ngati musanza mutatenga dacomitinib, musatengere mlingo wina nthawi yomweyo. Pitirizani dongosolo lanu lokhazikika.

Dokotala wanu akhoza kuyimitsa chithandizo chanu kwakanthawi kapena kosatha kapena kuchepetsa mlingo wanu ngati mukukumana ndi zovuta zina za dacomitinib. Uzani dokotala wanu momwe mukumvera mukamalandira chithandizo. Pitilizani kutenga dacomitinib ngakhale mukumva bwino. Osasiya kumwa dacomitinib osalankhula ndi dokotala.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge dacomitinib,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la dacomitinib, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a dacomitinib. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: antidepressants monga amitriptyline, clomipramine (Anafranil), desipramine (Norpramin), duloxetine (Cymbalta), fluoxetine (Prozac), imipramine (Tofranil), paroxetine (Paxil, Pexeva), ndi venlafaxine ); ma antipsychotic monga aripiprazole (Abilify), haloperidol (Haldol), risperidone (Risperdal), ndi thioridazine; atomoxetine (Strattera); zotchinga beta monga carvedilol (Coreg), metoprolol (Dutoprol), ndi timolol; codeine; dextromethorphan (yomwe imapezeka m'mankhwala ambiri a chifuwa; ku Nuedexta); flecainide (Tambocar); mexiletine; ondansetron (Zofran, Zuplenz); oxycodone (Oxaydo, Xtampza ER); propafenone (Rythmol SR); proton-pump inhibitors monga dexlanspoprazole (Dexilant), esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), ndi rabeprazole (AcipHex); tamoxifen (Soltamox); ndi tramadol (Conzip, Ultram). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• ngati mukumwa mankhwala a kudzimbidwa, kutentha pa chifuwa, kapena zilonda monga cimetidine (Tagamet), famotidine (Pepcid, in Duexis), nizatidine (Axid), kapena ranitidine (Zantac), tengani dacomitinib osachepera maola 6 isanakwane kapena osachepera 10 maola angapo mutamwa mankhwalawa.
• auzeni adotolo ngati mumakhala ndi matenda otsekula m'mimba pafupipafupi, matenda am'mapapo, mavuto opuma kupatula khansa ya m'mapapo, kapena chiwindi kapena matenda a impso.
• Uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati. Muyenera kuyezetsa musanalandire mankhwala. Simuyenera kutenga pakati mukatenga dacomitinib. Muyenera kugwiritsa ntchito njira yodalirika yolerera pamene mukumwa dacomitinib komanso kwa masiku osachepera 17 mutalandira mankhwala omaliza. Mukakhala ndi pakati mukatenga dacomitinib, itanani dokotala wanu mwachangu. Dacomitinib itha kuvulaza mwana wosabadwayo.
• Uzani dokotala wanu ngati mukuyamwitsa. Simuyenera kuyamwa mukamamwa dacomitinib komanso masiku 17 mutapatsidwa mankhwala omaliza.
• konzekerani kugwiritsa ntchito mafuta onunkhira, pewani kuwunika kosafunikira kapena kwakanthawi kwa dzuwa, komanso kuvala zovala zoteteza, magalasi a dzuwa, ndi zotchinga dzuwa. Dacomitinib imatha kupangitsa khungu lanu kumvetsetsa kuwala kwa dzuwa.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Pitani muyezo womwe mwaphonya ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Dacomitinib itha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kuonda
• kusowa chilakolako
• zilonda mkamwa
• matenda a khungu kuzungulira zikhadabo kapena zikhadabo za thupi
• kutayika tsitsi
• chifuwa
• kusowa mphamvu
• kuvuta kugona kapena kugona
• maso ofiira kapena otupa ("diso la pinki")
• kusintha kwa kukoma
• kusanza

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• kutsegula m'mimba
• kupuma movutikira, chifuwa, ndi malungo
• khungu louma, redness, zotupa, ziphuphu, khungu loyabwa, komanso khungu kapena khungu
• kupweteka pachifuwa

Dacomitinib ikhoza kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu adzaitanitsa mayeso a labu musanayambe mankhwala anu kuti muwone ngati khansa yanu ingathe kuthandizidwa ndi dacomitinib.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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