Daratumumab ndi Hyaluronidase-fihj jekeseni

Zamkati

• Asanalandire daratumumab ndi jakisoni wa hyaluronidase-fihj,
• Daratumumab ndi jakisoni wa hyaluronidase-fihj zitha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa m'gawo la HOW, itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi:

Daratumumab ndi jakisoni wa hyaluronidase-fihj amagwiritsidwa ntchito ndi mankhwala ena kuti athetse ma myeloma angapo (mtundu wa khansa ya m'mafupa) mwa achikulire omwe angopeza kumene omwe sangathe kulandira mankhwala ena. Daratumumab ndi jakisoni wa hyaluronidase-fihj imagwiritsidwanso ntchito limodzi ndi mankhwala ena kuti athetse ma myeloma ambiri mwa akulu omwe abwerera kapena sanasinthe atalandira mankhwala ena. Mankhwalawa amagwiritsidwanso ntchito payekha kuchiza achikulire omwe ali ndi myeloma angapo omwe alandila njira zitatu ndi mankhwala ena ndipo sanalandire chithandizo. Daratumumab ali mgulu la mankhwala otchedwa monoclonal antibodies. Zimagwira ntchito pothandiza thupi kuchepetsa kapena kuletsa kukula kwa maselo a khansa. Hyaluronidase-fihj ndi endoglycosidase. Zimathandiza kusunga daratumumab m'thupi nthawi yayitali kuti mankhwala azikhala ndi mphamvu zambiri.

Daratumumab ndi jakisoni wa hyaluronidase-fihj imabwera ngati yankho (madzi) kuti alandire jakisoni (pansi pa khungu) m'mimba (m'mimba) kupitilira 3 mpaka 5 mphindi. Kutalika kwa chithandizo chanu kumadalira momwe mulili komanso momwe thupi lanu limayankhira mukalandira chithandizo.

Dokotala kapena namwino adzakuyang'anirani mosamala mukalandira mankhwala ndipo pambuyo pake kuti awonetsetse kuti simukukhudzidwa ndi mankhwalawo. Mudzapatsidwa mankhwala ena othandiza kupewa ndi kuchiza zotsatira za daratumumab ndi hyaluronidase-fihj musanalandire mankhwala. Uzani dokotala wanu kapena namwino nthawi yomweyo ngati mukumane ndi izi: kupuma movutikira kapena kupuma movutikira, kupweteka pachifuwa, kupuma, kukhazikika pakhosi ndi kukwiya, kukhosomola, kuthamanga kapena mphuno yothina, kupweteka mutu, kuyabwa, nseru, kusanza, malungo, kuzizira , zotupa, ming'oma, kapena chizungulire kapena kupepuka.

Dokotala wanu akhoza kuyimitsa chithandizo chanu kwakanthawi kapena kosatha. Izi zimadalira momwe mankhwalawa amakuthandizirani komanso zovuta zomwe mumakumana nazo. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira chithandizo cha daratumumab ndi hyaluronidase-fihj. Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Asanalandire daratumumab ndi jakisoni wa hyaluronidase-fihj,

• Uzani dokotala ndi wazamankhwala ngati muli ndi matupi awo sagwirizana ndi daratumumab, hyaluronidase-fihj, mankhwala ena aliwonse, kapena zosakaniza zilizonse za daratumumab ndi jakisoni wa hyaluronidase-fihj. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• Uzani dokotala wanu ngati mwakhalapo ndi shingles (zotupa zopweteka zomwe zimachitika mutatha kutenga kachilombo ka herpes zoster kapena nkhuku), hepatitis B (kachilombo kamene kamayambitsa chiwindi ndipo kangayambitse chiwindi), kapena kupuma.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Muyenera kugwiritsa ntchito njira zakulera kuti muchepetse kutenga pakati mukamalandira daratumumab ndi hyaluronidase-fihj komanso kwa miyezi itatu mutatha kumwa. Lankhulani ndi dokotala wanu za mitundu yoletsa yomwe ingakuthandizeni. Mukakhala ndi pakati mukalandira jakisoni wa daratumumab ndi hyaluronidase-fihj, itanani dokotala wanu.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani adotolo kapena dokotala kuti mukulandira jakisoni wa daratumumab ndi hyaluronidase-fihj.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Daratumumab ndi jakisoni wa hyaluronidase-fihj zitha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kudzimbidwa
• kutsegula m'mimba
• kusanza
• nseru
• kupweteka m'mimba
• kusowa chilakolako
• kutopa
• kuvuta kugona kapena kugona
• kupweteka, kuwotcha, kapena kumva kulasalasa m'manja kapena m'mapazi
• kutupa kwa manja, akakolo, kapena mapazi
• kupweteka kwa msana
• kuyabwa, kutupa, kuphwanya, kapena kufiira kwa khungu pamalo obayira

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi kapena zomwe zalembedwa m'gawo la HOW, itanani dokotala wanu mwachangu kapena mupeze chithandizo chadzidzidzi:

• kuvulaza kapena kutuluka mwachilendo
• khungu lotuwa, kutopa, kapena kupuma movutikira
• maso achikaso kapena khungu; mkodzo wamdima; kapena kupweteka kapena kusapeza bwino kumtunda kwam'mimba

Daratumumab ndi jakisoni wa hyaluronidase-fihj zitha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukalandira mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu musanachitike komanso mukamalandira chithandizo kuti muwone momwe thupi lanu likuyankhira jakisoni wa daratumumab ndi hyaluronidase-fihj.

Daratumumab ndi hyaluronidase-fihj zitha kukhudza zotsatira zoyeserera magazi mukamalandira chithandizo komanso kwa miyezi 6 mutatha kumwa komaliza. Musanapatsidwe magazi, uzani dokotala wanu ndi ogwira ntchito ku labotale kuti mukulandira kapena kulandira daratumumab ndi jakisoni wa hyaluronidase-fihj. Dokotala wanu adzayesa magazi kuti agwirizane ndi mtundu wamagazi anu musanayambe chithandizo ndi daratumumab ndi hyaluronidase-fihj.

Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudza daratumumab ndi hyaluronidase-fihj.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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