Decitabine ndi Cedazuridine

Zamkati

• Musanatenge decitabine ndi cedazuridine,
• Decitabine ndi cedazuridine zimatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

Kuphatikiza kwa decitabine ndi cedazuridine kumagwiritsidwa ntchito pochiza mitundu ina ya matenda a myelodysplastic (mikhalidwe yomwe mafupa amatulutsa maselo amwazi omwe amasokonekera ndipo samatulutsa ma cell amwazi okwanira), kuphatikiza myelomonocytic leukemia (CMML) mwa akulu. Decitabine ali mgulu la mankhwala otchedwa hypomethylation agents. Zimagwira ntchito pothandiza mafupa kupanga maselo abwinobwino amwazi komanso kupha maselo osadziwika m'mafupa. Cedazuridine ali mgulu la mankhwala otchedwa cytidine deaminase inhibitors. Zimathandizira kukulitsa kuchuluka kwama decitabine mthupi kuti mankhwala azikhala ndi mphamvu yayikulu.

Kuphatikiza kwa decitabine ndi cedazuridine kumabwera ngati piritsi kuti mutenge pakamwa. Nthawi zambiri amatengedwa m'mimba yopanda kanthu kwa masiku asanu oyambira masiku 28. Musadye chakudya kwa maola 2 kale ndi maola awiri mutatha kumwa mankhwala. Ndondomeko yamasiku 28 azungulira imatha kubwerezedwa monga momwe adakulimbikitsira dokotala kutengera momwe thupi lanu likuyankhira mankhwalawa. Chithandizo nthawi zambiri chimaperekedwa kwa mphindi zosachepera 4 koma chitha kupitilizidwa ngati dokotala angaone kuti mupindula ndi chithandizo china.

Kumeza mapiritsi lonse; osagawana, kutafuna, kapena kuwaphwanya.

Ngati musanza mutatenga decitabine ndi cedazuridine, musamwe mlingo wina. Pitirizani dongosolo lanu lokhazikika.

Dokotala wanu adzakupatsani mankhwala kuti muchepetse kunyoza ndi kusanza musanalandire mlingo uliwonse wa decitabine ndi cedazuridine.

Dokotala wanu akhoza kuchepetsa mlingo wanu kapena kuimitsa kanthawi kochepa kapena kosatha ngati mukukumana ndi zovuta zina. Onetsetsani kuti muuze dokotala momwe mukumvera mukamalandira chithandizo cha decitabine ndi cedazuridine.

Funsani wamankhwala kapena dokotala wanu kuti mumupatseko zidziwitso za wopanga kwa wodwalayo.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge decitabine ndi cedazuridine,

• auzeni dokotala ndi wazamankhwala ngati muli ndi vuto la mankhwala a decitabine, cedazuridine, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a decitabine ndi cedazuridine. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• uzani dokotala wanu ngati mwakhalapo ndi matenda a impso kapena chiwindi.
• uzani dokotala wanu ngati muli ndi pakati kapena mukufuna kukhala ndi pakati, kapena ngati mukufuna kukhala ndi mwana. Ngati ndinu wamkazi, muyenera kuyezetsa asanayambe kulandira chithandizo ndikugwiritsa ntchito njira zakulera kuti muchepetse mimba mukamalandira chithandizo komanso kwa miyezi isanu ndi umodzi mutatha kumwa. Ngati ndinu wamwamuna, inu ndi mnzanuyo muyenera kugwiritsa ntchito njira yolerera pamene mukumwa decitabine ndi cedazuridine komanso kwa miyezi itatu mutalandira mankhwala omaliza. Ngati inu kapena mnzanu mumakhala ndi pakati mukamamwa mankhwalawa, itanani dokotala wanu. Decitabine ndi cedazuridine zitha kuvulaza mwana wosabadwayo.
• Uzani dokotala wanu ngati mukuyamwitsa. Musamwe mkaka pamene mukumwa decitabine ndi cedazuridine komanso kwa masabata awiri mutatha kumwa.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka mwa amuna. Lankhulani ndi dokotala wanu za kuopsa kwakumwa decitabine ndi cedazuridine.
• ngati mukuchitidwa opaleshoni, kuphatikizapo opaleshoni ya mano, uzani dokotala kapena dokotala kuti mukumwa decitabine ndi cedazuridine.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Ngati padutsa maola 12 kuchokera pomwe mudakonzekera kumwa mankhwalawo, imwani mlingo wopanda kanthu mukangokumbukira. Ngati kwadutsa maola opitilira 12, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika kuti mumalize mlingo wa 5 wa tsiku ndi tsiku. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Decitabine ndi cedazuridine zimatha kuyambitsa zovuta. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• kutopa kwambiri
• khungu lotumbululuka
• kudzimbidwa
• kutsegula m'mimba
• nseru
• kusanza
• kupweteka m'mimba
• kuonda
• kusowa chilakolako
• kulumikizana kapena kupweteka kwa minofu
• chizungulire
• kugwa pansi
• mutu
• kuvuta kugona kapena kugona
• zilonda zopweteka mkamwa, kapena lilime kapena milomo
• kutupa kwa manja, mapazi, akakolo, miyendo yakumunsi, kapena m'mimba
• kumva kulasalasa, kuchita dzanzi, ndi kupweteka m'manja kapena m'mapazi

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi zina mwazizindikirozi, pitani kuchipatala nthawi yomweyo kapena pitani kuchipatala:

• malungo, kuzizira, chifuwa, kupweteka kwa thupi, kapena zizindikilo zina za matenda
• kutuluka mwachilendo kapena kuphwanya, kutuluka magazi m'mphuno, kapena m'kamwa
• kuthamanga kapena kugunda kwamtima
• kupuma movutikira
• zidzolo

Decitabine ndi cedazuridine zimatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu musanachitike komanso mukamalandira chithandizo kuti muwone momwe thupi lanu likuyankhira decitabine ndi cedazuridine.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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