Hydroxyurea

Zamkati

• Musanatenge hydroxyurea,
• Hydroxyurea imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:
• Zizindikiro za bongo zingaphatikizepo izi:

Hydroxyurea imatha kuchepa kwambiri pamaselo amwazi m'mafupa anu. Izi zitha kuwonjezera chiopsezo kuti mutenge matenda akulu kapena magazi. Ngati mukumane ndi izi, itanani dokotala wanu nthawi yomweyo: malungo, kuzizira, kutopa kwambiri kapena kufooka, kupweteka kwa thupi, zilonda zapakhosi, kupuma movutikira, kutsokomola kosalekeza komanso kuchulukana, kapena zizindikilo zina za matenda; kutuluka mwachilendo kapena kuvulala; wamagazi kapena wakuda, malo obisalira; kapena kusanza magazi kapena zinthu zofiirira zomwe zikufanana ndi khofi.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena nthawi ndi nthawi kuti aone momwe thupi lanu likuyankhira ku hydroxyurea ndikuwona ngati kuchuluka kwamagazi anu kwatsika. Dokotala wanu angafunike kuti asinthe mlingo wanu kapena akuuzeni kuti musiye kumwa hydroxyurea kwakanthawi kuti magazi anu abwerere mwakale ngati atsika kwambiri.

Hydroxyurea ingawonjezere chiopsezo choti mungakhale ndi khansa zina, kuphatikiza khansa yapakhungu. Konzekerani kupewa kupezeka kwa dzuwa mosafunikira kapena motalika komanso kuvala zovala zoteteza, magalasi a dzuwa, ndi zotchingira dzuwa. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito hydroxyurea.

Dokotala wanu kapena wamankhwala adzakupatsani pepala lazidziwitso za wopanga (Medication Guide) mukayamba mankhwala ndi hydroxyurea ndipo nthawi iliyonse mukamadzaza mankhwala anu. Werengani nkhaniyi mosamala ndikufunsani dokotala kapena wamankhwala ngati muli ndi mafunso. Muthanso kuyendera tsamba la Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kuti mupeze Chithandizo cha Mankhwala.

Hydroxyurea (Hydrea) imagwiritsidwa ntchito payokha kapena ndi mankhwala ena kapena mankhwala a radiation kuti athetse mtundu wina wamatenda am'magazi am'mimba (CML; mtundu wa khansa yamagazi oyera) ndi mitundu ina ya khansa yamutu ndi khosi (kuphatikiza khansa ya mkamwa , tsaya, lilime, mmero, matumbo, ndi sinus). Hydroxyurea (Droxia, Siklos) amagwiritsidwa ntchito pochepetsa kuchepa kwamatenda opweteka ndikuchepetsa kufunika kwa kuthiridwa magazi kwa akulu ndi ana azaka ziwiri kapena kupitilira apo omwe ali ndi sickle cell anemia (matenda amwazi wobadwa nawo momwe maselo ofiira ofiira amapangidwa modabwitsa [wopangidwa ngati chikwakwa] ndipo sangathe kubweretsa mpweya wokwanira m'zigawo zonse za thupi). Hydroxyurea ili mgulu la mankhwala otchedwa antimetabolites. Hydroxyurea imathandizira khansa pochepetsa kapena kuletsa kukula kwa maselo a khansa mthupi lanu. Hydroxyurea imathandizira kuchepa kwa kuchepa kwama cell cell pothandiza kupewa kupangika kwa maselo ofiira ofiira ngati chikwakwa.

Hydroxyurea imabwera ngati kapisozi ndi piritsi yotenga pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku ndi kapu yamadzi. Hydroxyurea ikagwiritsidwa ntchito pochiza mitundu ina ya khansa, imatha kumwedwa kamodzi tsiku lililonse. Tengani hydroxyurea mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani hydroxyurea ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.

Dokotala wanu angafunikire kuchedwetsa chithandizo chanu kapena kusintha mlingo wa hydroxyurea kutengera momwe mungayankhire ndi zomwe mungakumane nazo. Lankhulani ndi dokotala wanu za momwe mukumvera mukamalandira chithandizo. Osasiya kumwa hydroxyurea osalankhula ndi dokotala.

Dokotala wanu angakuuzeni kuti mutenge mankhwala ena, folic acid (vitamini), kuti muchepetse zovuta zina za mankhwalawa. Tengani mankhwalawa ndendende monga momwe adanenera.

Kumeza makapisozi lonse; osagawana, kutafuna, kapena kuwaphwanya.

Mapiritsi a hydroxyurea 1,000-mg (Siklos) amathandizidwa kuti azitha kugawidwa m'magawo awiri kapena pang'ono kuti apereke zochepa. Osathyola mapiritsi a hydroxyurea 100-mg m'magawo ang'onoang'ono. Dokotala wanu adzakuuzani momwe mungaphwanyire mapiritsi ndi kuchuluka kwa mapiritsi kapena magawo a piritsi omwe muyenera kumwa.

Ngati mukulephera kumeza mapiritsi a hydroxyurea kapena magawo (ena) a mapiritsi, mutha kusungunula mulingo wanu m'madzi. Ikani mlingo wanu mu supuni ndi kuwonjezera madzi pang'ono. Dikirani pafupifupi 1 miniti kuti pulogalamu yanu isungunuke, kenako kumeza chisakanizo nthawi yomweyo.

Muyenera kuvala magulovu kapena magolovesi a latex mukamagwiritsa makapisozi kapena mapiritsi kuti khungu lanu lisakhudzane ndi mankhwalawa. Sambani m'manja ndi sopo musanakhudze botolo kapena mankhwala. Ngati hydroxyurea ilowa m'maso mwanu, nthawi yomweyo tsitsani maso anu ndi madzi kwa mphindi zosachepera 15. Ngati ufa watuluka mu kapisozi kapena piritsi litayikira, pukutani nthawi yomweyo ndi chopukutira chonyowa chomwe mungataye. Kenako ikani chopukutira m'chiboda chotsekedwa, monga thumba la pulasitiki, ndikutaya mu chidebe chomwe sichingathe kufikiridwa ndi ana ndi ziweto. Sambani malo omwe mwataya pogwiritsa ntchito mankhwala otsekemera otsatiridwa ndi madzi oyera.

Hydroxyurea imagwiritsidwanso ntchito pochiza polycythemia vera (matenda amwazi momwe thupi lanu limapanga maselo ofiira ochulukirapo). Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito mankhwalawa ngati muli ndi vuto lanu.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge hydroxyurea,

• uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la hydroxyurea, mankhwala ena aliwonse, kapena zina zilizonse zosagwiritsidwa ntchito m'mapiritsi a hydroxyurea. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: mankhwala ena a kachilombo ka HIV (kachilombo ka HIV) monga didanosine (Videx) ndi stavudine (Zerit) ndi interferon (Actimmune, Avonex, Betaseron, Infergen, Intron A, ena). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• auzeni adotolo ngati muli ndi kachilombo ka HIV, muli ndi matenda a immunodeficiency (AIDS), kuchuluka kwa uric acid m'magazi anu, kapena zilonda zam'miyendo; ngati mukuchiritsidwa kapena mwakhalapo ndi mankhwala a radiation, khansa chemotherapy, kapena hemodialysis; kapena ngati mwakhalapo ndi matenda a impso kapena chiwindi.
• Uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Simuyenera kutenga pakati kapena kuyamwitsa mukamamwa hydroxyurea. Muyenera kuyezetsa mimba musanayambe mankhwala ndi hydroxyurea. Ngati ndinu wamkazi, muyenera kugwiritsa ntchito njira yolerera yoyera mukamamwa hydroxyurea komanso kwa miyezi yosachepera 6 mutasiya kumwa mankhwala. Ngati ndinu wamwamuna, inu ndi mnzanuyo muyenera kugwiritsa ntchito njira zolerera mukamamwa hydroxyurea komanso kwa miyezi isanu ndi umodzi (Siklos) kapena chaka chimodzi (Droxia, Hydrea) mutasiya kumwa mankhwala. Lankhulani ndi dokotala wanu za njira zolerera zomwe mungagwiritse ntchito mukamalandira chithandizo komanso mukalandira chithandizo komanso kuti mupitilize kugwiritsa ntchito nthawi yayitali bwanji. Mukakhala ndi pakati mukatenga hydroxyurea, itanani dokotala wanu mwachangu. Hydroxyurea itha kuvulaza mwana wosabadwayo.
• Muyenera kudziwa kuti mankhwalawa amachepetsa kubereka mwa amuna. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito hydroxyurea.
• mulibe katemera popanda kulankhula ndi dokotala.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Hydroxyurea imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kusanza
• kutsegula m'mimba
• kusowa chilakolako
• kunenepa
• zilonda mkamwa ndi pakhosi
• kudzimbidwa
• zidzolo
• khungu lotumbululuka
• chizungulire
• mutu
• kutayika tsitsi
• kusintha kwa khungu ndi misomali

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi kapena izi zomwe zalembedwa M'CHENJEZO CHOFUNIKA, itanani dokotala wanu mwachangu kapena pitani kuchipatala mwadzidzidzi:

• kugunda kwamtima mwachangu
• kupweteka komwe kumayambira m'mimba koma kumafalikira kumbuyo
• mabala a mwendo kapena zilonda
• kupweteka, kuyabwa, kufiira, kutupa, kapena matuza pakhungu
• kupweteka kumtunda chakumanja kwam'mimba
• chikasu cha khungu kapena maso
• dzanzi, kutentha, kapena kumva kulasalasa m'manja kapena m'mapazi
• malungo, chifuwa, kupuma movutikira, ndi mavuto ena opuma

Hydroxyurea imatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, ndipo ana ndi ziweto sangathe kuzipeza. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Mapiritsi osweka a 1,000-mg ayenera kusungidwa mchidebecho ndipo ayenera kugwiritsidwa ntchito pasanathe miyezi itatu.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• zilonda mkamwa ndi pakhosi
• kupweteka, kufiira, kutupa, ndi kukulira m'manja ndi m'mapazi
• mdima wa khungu

Musanapite kukayezetsa labotale, auzeni dokotala ndi ogwira nawo ntchito kuti mukumwa hydroxyurea.

Musalole kuti aliyense azimwa mankhwala anu.Anthu omwe samamwa hydroxyurea ayenera kupewa kukhudza mankhwalawo kapena botolo lomwe lili ndi mankhwalawa.

Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Droxia^®
• Hydrea^®
• Siklos^®

• Hydroxycarbamide