Etidronate

Zamkati

• Etidronate mwina singagwire bwino ntchito ndipo imatha kuwononga kholingo (chubu cholumikiza mkamwa ndi m'mimba) kapena kuyambitsa zilonda mkamwa ngati singatengedwe molingana ndi malangizo awa. Uzani dokotala wanu ngati simukumvetsa, mukuganiza kuti simukumbukira, kapena simungathe kutsatira malangizo awa:
• Musanatenge etidronate,
• Etidronate imatha kubweretsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo:
• Zizindikiro za bongo zingaphatikizepo izi:

Etidronate amagwiritsidwa ntchito pochiza matenda a Paget a mafupa (momwe mafupa amafewa ndi ofooka ndipo amatha kupunduka, opweteka, kapena osweka mosavuta) komanso kupewa ndi kuchiza heterotopic ossification (kukula kwa mafupa m'dera la thupi kuposa mafupa) mwa anthu omwe achita opaleshoni yonse ya mchiuno (opaleshoni m'malo mwa chiuno ndi cholumikizira) kapena mwa anthu omwe avulala kumsana. Etidronate ali mgulu la mankhwala otchedwa bisphosphonates. Zimagwira ntchito pochepetsa kuwonongeka kwa mafupa akale ndikupanga fupa latsopano.

Etidronate imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kamodzi patsiku pamimba yopanda kanthu. Chithandizo cha matenda a Paget chitha kubwerezedwa ngati zizindikiro zibwereranso kapena zikuipiraipira pakapita nthawi. Tengani etidronate mozungulira nthawi yomweyo tsiku lililonse. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani etidronate ndendende momwe mwalangizira. Musamamwe pang'ono kapena kumamwa pafupipafupi kapena kwa nthawi yayitali kuposa momwe adalangizira dokotala.

Etidronate mwina singagwire bwino ntchito ndipo imatha kuwononga kholingo (chubu cholumikiza mkamwa ndi m'mimba) kapena kuyambitsa zilonda mkamwa ngati singatengedwe molingana ndi malangizo awa. Uzani dokotala wanu ngati simukumvetsa, mukuganiza kuti simukumbukira, kapena simungathe kutsatira malangizo awa:

• Kumeza mapiritsiwo ndi kapu yathunthu (180 mpaka 240 mL) yamadzi opanda madzi mukakhala pansi kapena mukuimirira.
• Khalani kapena kuyimirira pomwepo mutatenga etidronate.
• Musadye, kumwa, kapena kumwa mankhwala ena aliwonse (kuphatikiza mavitamini kapena maantacid) kwa maola 2 musanadye komanso maola awiri mutamwa etidronate.

Ngati mukumwa etidronate kuchiza matenda a mafupa a Paget kapena kupewa kapena kuchiza matenda a heterotopic ossification, zingatenge nthawi kuti vuto lanu likhale bwino. Osasiya kumwa etidronate osalankhula ndi dokotala.

Etidronate imagwiritsidwanso ntchito nthawi zina kuchiza ndikupewa kufooka kwa mafupa (komwe mafupa amafooka komanso kufooka ndipo amatha kutuluka mosavuta) chifukwa cha corticosteroids (mtundu wa mankhwala omwe angayambitse kufooka kwa mafupa). Lankhulani ndi dokotala wanu za kuopsa kokugwiritsa ntchito mankhwalawa.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge etidronate,

• Uzani dokotala ndi wazamankhwala ngati muli ndi vuto la etidronate, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a etidronate. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
• Uzani dokotala wanu komanso wamankhwala mankhwala ndi mankhwala osapatsirana, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: angiogenesis inhibitors monga bevacizumab (Avastin), everolimus (Afinitor, Zortress), pazopanib (Votrient), sorafenib (Nexavar), kapena sunitinib (Sutent); maanticoagulants ('oonda magazi') monga warfarin (Coumadin, Jantoven); khansa chemotherapy; ndi steroids amlomo monga dexamethasone, methylprednisolone (Medrol), ndi prednisone (Rayos). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• ngati mukumwa zowonjezera mavitamini ndi mchere monga chitsulo, kapena ngati mukumwa maantacid okhala ndi calcium, magnesium, kapena aluminium (Maalox, Mylanta, Tums, ena), tengani maola awiri musanadye kapena maola awiri mutatenga etidronate.
• auzeni adotolo ngati mwakhala mukukumana ndi mavuto am'mimba ngati matenda am'mimba (kuchepa kwa m'mimba komwe kumayambitsa mavuto akumeza) kapena achalasia (vuto lomwe limakhudza kutsekula kosunthira chakudya kumimba), kapena osteomalacia (kufewetsa mafupa chifukwa chosowa mchere). Dokotala wanu angakuuzeni kuti musatenge etidronate.
• auzeni adotolo ngati mukulephera kukhala kapena kuimirira ndipo ngati mudakhalapo kapena mudakhalapo ndi kuchepa kwa magazi (momwe maselo ofiira samabweretsa mpweya wokwanira kumadera onse amthupi); kashiamu wotsika m'magazi anu; zovuta kumeza, kutentha pa chifuwa, zilonda zam'mimba, kapena mavuto ena am'mimba; khansa; enterocolitis (kutupa m'matumbo); matenda amtundu uliwonse, makamaka mkamwa mwanu; mavuto pakamwa panu, mano, kapena m'kamwa; vuto lililonse lomwe limaletsa magazi anu kuti asagundike bwino; kapena matenda a impso. Dokotala wanu angafunike kusintha mlingo wa mankhwala anu kapena kukuyang'anirani mosamala zotsatira zake.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Komanso muuzeni dokotala ngati mukufuna kukhala ndi pakati nthawi iliyonse m'tsogolo chifukwa etidronate imatha kukhala mthupi lanu kwazaka zambiri mutasiya kuidya. Itanani dokotala wanu mukakhala ndi pakati mukamalandira mankhwala ndi etidronate.
• muyenera kudziwa kuti etidronate imatha kuyambitsa mafupa a nsagwada (ONJ, vuto lalikulu la fupa la nsagwada), makamaka ngati mwachitidwa opareshoni yamazinyo kapena chithandizo mukamamwa mankhwalawa. Dokotala wamano ayenera kuwerengera mano anu ndikuchita chithandizo chilichonse chofunikira, kuphatikiza kuyeretsa kapena kukonza mano oyenera, musanayambe kumwa etidronate. Onetsetsani kutsuka mano ndikutsuka mkamwa mwanu bwino mukamamwa etidronate. Lankhulani ndi dokotala musanalandire chithandizo chilichonse cha mano mukamamwa mankhwalawa.
• muyenera kudziwa kuti etidronate imatha kupweteketsa mafupa, minofu, kapena mafupa. Mutha kuyamba kumva kuwawa pasanathe masiku, miyezi, kapena zaka mutangotenga etidronate. Ngakhale kupweteka kwamtunduwu kumatha kuyamba mutatenga etidronate kwakanthawi, ndikofunikira kuti inu ndi dokotala muzindikire kuti mwina imayambitsidwa ndi etidronate. Itanani dokotala wanu nthawi yomweyo ngati mukumva kuwawa kwambiri nthawi iliyonse mukamachiritsidwa ndi etidronate. Dokotala wanu angakuuzeni kuti musiye kumwa etidronate ndipo ululu wanu ukhoza kutha mukasiya kumwa mankhwalawo.

Ndikofunika kuti mupeze calcium ndi vitamini D wokwanira ndikudya chakudya choyenera mukamamwa etidronate. Dokotala wanu angakuuzeni kuti ndi zakudya ziti zomwe zimapatsa thanzi komanso kuchuluka kwa zosowa zanu tsiku lililonse. Ngati zikukuvutani kudya zakudya zokwanira, uzani dokotala wanu. Zikatero, dokotala wanu akhoza kukupatsirani mankhwala kapena akuwonjezerani chowonjezera.

Ngati simunadye kale, tengani mlingo womwe mwaphonya mukangokumbukira. Ngati mwadya kale, imwani mlingo wa maola 2 musanadye kudya. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Etidronate imatha kubweretsa zovuta zina. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• nseru
• kutsegula m'mimba

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo:

• kutentha pa chifuwa kwatsopano kapena kukulira
• ululu mukameza
• kupweteka pachifuwa
• kutupa kwa nkhope, mmero, lilime, milomo, maso, manja, mapazi, akakolo, kapena miyendo yakumunsi
• ukali
• zovuta kumeza
• matuza pakhungu

Etidronate imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo izi:

• kusanza
• kukokana m'mimba
• kutsegula m'mimba
• kupweteka, kuwotcha, kuchita dzanzi, kapena kumva kupweteka m'manja kapena m'mapazi
• kutuluka kwa minofu ndi kukokana

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amatha kuyitanitsa mayeso ena a labu kuti muwone kuyankha kwa thupi lanu ku etidronate.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Didronel^®

• EHDP