Selegiline

Zamkati

• Musanatenge selegiline,
• Selegiline angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:
• Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo:
• Zizindikiro za bongo zingaphatikizepo:

Selegiline amagwiritsidwa ntchito kuthandizira kuwongolera zizindikilo za matenda a Parkinson (PD; vuto lamanjenje lomwe limayambitsa zovuta poyenda, kuwongolera minofu, ndi kusinthanitsa) mwa anthu omwe akutenga levodopa ndi carbidopa kuphatikiza (Sinemet). Selegiline atha kuthandiza anthu omwe ali ndi matenda a Parkinson pochepetsa kuchepa kwa levodopa / carbidopa yofunikira kuwongolera zizindikilo, kuletsa zotsatira za levodopa / carbidopa kuchoka pakati pa mankhwala, ndikuwonjezera kutalika kwa nthawi yomwe levodopa / carbidopa ipitilizabe kuwongolera zizindikilo. Selegiline ali mgulu la mankhwala otchedwa monoamine oxidase type B (MAO-B) inhibitors. Zimagwira ndikuwonjezera kuchuluka kwa dopamine (chinthu chachilengedwe chomwe chimafunikira kuwongolera mayendedwe) muubongo.

Selegiline amabwera ngati kapisozi komanso piritsi losungunuka pakamwa kuti atenge pakamwa. Kapisozi nthawi zambiri amatengedwa kawiri patsiku ndi chakudya cham'mawa komanso nkhomaliro. Piritsi lomwe limasweka pakamwa nthawi zambiri limatengedwa kamodzi patsiku musanadye chakudya cham'mawa popanda chakudya, madzi, kapena zakumwa zina. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani selegiline ndendende monga momwe adauzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala. Mukatenga selegiline wochulukirapo, mutha kukhala ndi chiwopsezo chadzidzidzi komanso chowopsa m'mwazi wanu.

Ngati mukumwa piritsi lomwe likumwazika pakamwa, musachotse chithuza chomwe chili ndi mapiritsi kuchokera m'thumba lakunja mpaka mutakonzeka kumwa mankhwala. Nthawi yakwana yoti mulandire mlingo, chotsani chithuza kuchokera m'thumba lakunja ndikugwiritsa ntchito manja owuma kuti mutsegule blister imodzi. Musayese kukankhira piritsi kudzera pa zojambulazo. Ikani piritsi lilime lanu ndikudikirira kuti lisungunuke. Osameza piritsi. Musadye kapena kumwa chilichonse kwa mphindi 5 musanamwe piritsi komanso kwa mphindi 5 mutamwa piritsi.

Ngati mukumwa piritsi lomwe likumwazika pakamwa, dokotala wanu akhoza kukuyambitsani pamlingo wochepa wa selegiline ndikuwonjezera mlingo wanu pakatha milungu isanu ndi umodzi.

Uzani dokotala wanu ngati mukumana ndi nseru, kupweteka m'mimba, kapena chizungulire. Dokotala wanu akhoza kuchepetsa mlingo wanu wa levodopa / carbidopa mukamachiza ndi selegiline, makamaka ngati mukukumana ndi izi kapena zizindikilo zina zachilendo. Tsatirani malangizowa mosamala ndikufunsani dokotala kapena wamankhwala ngati simukudziwa kuchuluka kwa mankhwala omwe muyenera kumwa. Musasinthe Mlingo wamankhwala anu aliwonse pokhapokha dokotala atakuuzani kuti muyenera kutero.

Selegiline atha kuthandizira kuwongolera zizindikiro za PD, koma sizingathetse vutoli. Osasiya kumwa selegiline osalankhula ndi dokotala. Mukasiya kumwa mankhwala mwadzidzidzi a matenda a Parkinson monga selegiline, mutha kukhala ndi malungo, thukuta, minofu yolimba, ndikumwalira. Itanani dokotala wanu ngati mukukumana ndi izi kapena zina mwazizindikiro mukasiya kumwa selegiline.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge selegiline,

• uzani dokotala wanu komanso wamankhwala ngati mukugwirizana ndi selegiline, kapena mankhwala ena aliwonse.
• auzeni adotolo ngati mukumwa, mwangotenga kumene, kapena mukufuna kumwa mankhwala aliwonse otsatirawa ndi osapereka mankhwala: dextromethorphan (Robitussin); meperidine (Demerol); methadone (Dolophine), propoxyphene (Darvon); tramadol (Ultram, mu Ultracet); ndi mankhwala ena omwe ali ndi selegiline (Eldepryl, Emsam, Zelapar). Dokotala wanu angakuuzeni kuti musatenge selegiline ngati mukumwa kapena mwangomwako kumene mankhwalawa. Mukasiya kumwa selegiline, adokotala angakuwuzeni kuti musamwe mankhwalawa mpaka masiku 14 atadutsa kuchokera pomwe mudatenga selegiline.
• auzeni dokotala ndi wazamankhwala mankhwala omwe akupatsani, osavomerezeka, mavitamini, zowonjezera zakudya, ndi mankhwala azitsamba omwe mukumwa. Onetsetsani kuti mwatchulapo izi: antidepressants monga amitriptyline (Elavil) ndi imipramine (Tofranil); carbamazepine (Carbatrol, Equetro); mankhwala a chifuwa ndi kuzizira kapena kuchepa thupi; nafcillin; phenobarbital; phenytoin (Dilantin); serotonin reuptake inhibitors monga citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), ndi sertraline (Zoloft); ndi rifampin (Rifadin, Rimactane). Dokotala wanu angafunike kusintha kuchuluka kwa mankhwala anu kapena kukuyang'anirani mosamala pazotsatira.
• auzeni adotolo ngati mwadwalapo chiwindi kapena impso.
• ngati muli ndi phenylketonuria (PKU; mkhalidwe wobadwa nawo momwe muyenera kudya chakudya chapadera kuti muchepetse kuchepa kwamaganizidwe), muyenera kudziwa kuti mapiritsi omwe amawonongeka pakamwa ali ndi phenylalanine.
• uzani dokotala wanu ngati muli ndi pakati, konzekerani kutenga pakati, kapena mukuyamwitsa. Mukakhala ndi pakati mukatenga selegiline, itanani dokotala wanu.
• muyenera kudziwa kuti selegiline imatha kuyambitsa chizungulire, mutu wopepuka, komanso kukomoka mukaimirira mwachangu pamalo abodza. Izi ndizofala kwambiri mukayamba kumwa selegiline. Pofuna kupewa vutoli, tulukani pabedi pang'onopang'ono, ndikupumitsa mapazi anu pansi kwa mphindi zingapo musanayimirire.

Funsani dokotala ngati mukufuna kupewa zakudya zilizonse mukamalandira mankhwala a selegiline. Dokotala wanu angakuwuzeni kuti mutha kupitiriza kudya zakudya zabwino bola mukatenga selegiline ndendende momwe mwalangizira.

Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wanu wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika.Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Selegiline angayambitse mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

• chizungulire
• wamisala
• kukomoka
• pakamwa pouma
• nseru
• kusanza
• kupweteka m'mimba
• zovuta kumeza
• kutentha pa chifuwa
• kutsegula m'mimba
• mpweya
• kudzimbidwa
• kuvuta kugona kapena kugona
• maloto achilendo
• kugona
• kukhumudwa
• ululu, makamaka m'miyendo kapena kumbuyo
• kupweteka kwa minofu kapena kufooka
• zofiirira pakhungu
• zidzolo
• kufiira, kuyabwa, kapena zilonda mkamwa (ngati mukumwa mapiritsi omwe amawonongeka pakamwa)

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukukumana ndi izi, uzani dokotala nthawi yomweyo:

• mutu wopweteka kwambiri
• kupweteka pachifuwa
• kuthamanga, kusasinthasintha, kapena kugunda kwamtima
• thukuta
• mwadzidzidzi, nseru komanso kusanza
• chisokonezo
• ouma kapena opweteka khosi
• kugwedezeka kosalamulirika kwa gawo lina la thupi lanu
• mayendedwe achilendo ovuta kuwongolera
• kuyerekezera zinthu m'maganizo (kuwona chinthu kapena mawu akumva omwe kulibe)
• kuvuta kupuma

Anthu omwe ali ndi PD atha kukhala ndi chiopsezo chowonjezeka chotenga melanoma (mtundu wa khansa yapakhungu). Palibe chidziwitso chokwanira chodziwitsa ngati selegiline kapena mankhwala ena a PD amachulukitsa chiopsezo cha khansa ya khansa. Lankhulani ndi dokotala wanu za kuopsa kogwiritsa ntchito selegiline komanso ngati muyenera kuyezetsa khungu lanu mukamamwa mankhwala.

Selegiline amatha kuyambitsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa). Chotsani mapiritsi osagwiritsidwa ntchito pakamwa patatha miyezi itatu mutatsegula thumba lanu.

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Zizindikiro za bongo zingaphatikizepo:

• Kusinza
• chizungulire
• kukomoka
• kupsa mtima
• kusakhudzidwa
• kubvutika
• mutu wopweteka kwambiri
• kuyerekezera zinthu m'maganizo (kuwona zinthu kapena kumva mawu omwe kulibe)
• kulimba kwa nsagwada
• kuuma ndi kupindika kumbuyo
• kugwidwa
• chikomokere (kutaya chidziwitso kwakanthawi)
• kusakhazikika kwachangu komanso kosasinthasintha
• kupweteka pachifuwa
• kupuma pang'ono
• thukuta
• malungo
• kozizira, khungu lamadzi

Sungani maimidwe onse ndi dokotala wanu.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

• Mphatso^®
• Zelapar^®