Mlembi: Janice Evans
Tsiku La Chilengedwe: 3 Kulayi 2021
Sinthani Tsiku: 18 Novembala 2024
Anonim
Enzalutamide preferable to bicalutamide plus LHRH analogue in prostate cancer
Kanema: Enzalutamide preferable to bicalutamide plus LHRH analogue in prostate cancer

Zamkati

Bicalutamide imagwiritsidwa ntchito ndi mankhwala ena (gonadotropin-release hormone (GnRH) agonists; monga leuprolide kapena goserelin) kuchiza khansa ya prostate (khansa yomwe idayamba mu prostate ndipo yafalikira mbali zina za thupi). Bicalutamide ali mgulu la mankhwala otchedwa nonsteroidal antiandrogens. Zimagwira ntchito poletsa zotsatira za androgen (mahomoni amphongo), kuti athetse kukula ndi kufalikira kwa maselo a khansa.

Bicalutamide imabwera ngati piritsi kuti itenge pakamwa. Nthawi zambiri amatengedwa kapena wopanda chakudya kamodzi patsiku, mwina m'mawa kapena madzulo. Tengani bicalutamide mozungulira nthawi yomweyo tsiku lililonse. Muyenera kuyamba kumwa bicalutamide tsiku lomwelo mukayamba jakisoni yotulutsa mahomoni otulutsa luteinizing. Tsatirani malangizo omwe mwalandira mosamala, ndikufunsani dokotala kapena wamankhwala kuti afotokoze gawo lililonse lomwe simukumvetsa. Tengani bicalutamide ndendende monga momwe akuuzira. Musamamwe pang'ono kapena kumamwa pafupipafupi kuposa momwe adanenera dokotala.


Bicalutamide limodzi ndi hormone yotulutsa mahomoni yotulutsa luteinizing itha kuyimitsa kukula ndi kufalikira kwa maselo a khansa koma siyichiza khansa ya prostate. Pitirizani kumwa onse bicalutamide ndi mahomoni otulutsa mahomoni a luteinizing ngakhale mutakhala bwino. Osasiya kumwa mankhwalawa osalankhula ndi dokotala.

Mankhwalawa amatha kupatsidwa ntchito zina; funsani dokotala wanu kapena wamankhwala kuti mudziwe zambiri.

Musanatenge bicalutamide,

  • uzani dokotala wanu komanso wamankhwala ngati muli ndi vuto la bicalutamide, mankhwala ena aliwonse, kapena zosakaniza zilizonse m'mapiritsi a bicalutamide. Funsani wamankhwala wanu kuti awonetse mndandanda wazosakaniza.
  • auzeni adotolo komanso asayansi yanu mankhwala ena omwe mungalandire kapena omwe simukulembera, mavitamini, zowonjezera zakudya, komanso mankhwala azitsamba omwe mukumwa kapena omwe mukufuna kumwa. Onetsetsani kuti mwatchulapo izi: alprazolam (Xanax); anticoagulants ('magazi ochepetsa magazi') monga warfarin (Coumadin); aripiprazole (Limbikitsani); buspirone (Buspar); zotsekemera za calcium monga amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac), felodipine (Plendil), nifedipine (Adalat, Procardia), nisoldipine (Sular), ndi verapamil (Calan, Covera, Isoptin, Verelan); mankhwala enaake; mankhwala ochepetsa mafuta m'thupi (ma statins) monga atorvastatin (Lipitor), lovastatin (Mevacor), ndi simvastatin (Zocor); clarithromycin (Biaxin); cyclosporine (Neoral, Sandimmune); diazepam (Valium); erythromycin (EES, E-Mycin, Erythrocin); HIV protease inhibitors monga indinavir (Crixivan), ritonavir (Norvir), ndi saquinavir (Invirase, Fortovase); methadone (Dolophine); midazolam (Ndime); pimozide (Orap); quinidine (Quinidex, Quinaglute); quinine; sildenafil (Viagra); tacrolimus (Prograf); tamoxifen (Nolvadex); telithromycin (Ketek); trazodone (Desyrel); katatu (Halcion); ndi vincristine (Vincasar). Mankhwala ena ambiri amathanso kulumikizana ndi bicalutamide, chifukwa chake onetsetsani kuti muwauze adotolo za mankhwala omwe mukumwa, ngakhale omwe sapezeka pamndandandawu.
  • uzani dokotala wanu ngati mwakhalapo kapena mudakhalapo ndi matenda a chiwindi.
  • muyenera kudziwa kuti bicalutamide imangogwiritsidwa ntchito mwa amuna. Ngati amatengedwa ndi amayi apakati, bicalutamide imatha kuyambitsa zovuta mu mwana wosabadwayo. Amayi omwe ali ndi pakati kapena atha kutenga pakati sayenera kumwa bicalutamide. Mukatenga bicalutamide muli ndi pakati, itanani dokotala wanu mwachangu.

Pokhapokha dokotala atakuwuzani zina, pitirizani kudya zomwe mumadya.


Tengani mlingo womwe mwaphonya mukangokumbukira. Komabe, ngati ili pafupi nthawi ya mlingo wotsatira, dumpha mlingo womwe umasowa ndikupitiliza dongosolo lanu lokhazikika. Musatenge mlingo wawiri kuti mupange omwe mwaphonya.

Bicalutamide imatha kuyambitsa mavuto. Uzani dokotala wanu ngati zina mwazizindikirozi ndizolimba kapena sizichoka:

  • kutentha kapena kutentha
  • fupa, kumbuyo, kapena kupweteka kwa m'chiuno
  • kufooka kwa minofu
  • kupweteka kwa minofu kapena molumikizana
  • mutu
  • kupuma movutikira
  • kuthamanga kwa magazi
  • kutupa kwa manja, mapazi, akakolo, kapena miyendo yakumunsi
  • chifuwa
  • kudzimbidwa
  • nseru
  • kusanza
  • kupweteka m'mimba
  • kutsegula m'mimba
  • mpweya
  • kusintha kunenepa (kutaya kapena kupindula)
  • kusowa chilakolako
  • chizungulire
  • kupweteka, kuwotcha, kapena kumva kulasalasa m'manja kapena m'mapazi
  • kuvuta kugona
  • kumva kusowa mtendere kapena mantha
  • zidzolo
  • thukuta
  • Kulephera kupeza kapena kusunga erection
  • amafunika kukodza pafupipafupi usiku
  • mkodzo wamagazi
  • pokodza kowawa kapena kovuta
  • pafupipafupi komanso mwachangu kufunika kokodza
  • kuvuta kutulutsa chikhodzodzo
  • mabere owawa kapena otupa

Zotsatira zina zoyipa zingakhale zazikulu. Ngati mukumane ndi izi, itanani dokotala nthawi yomweyo:

  • chikasu cha khungu kapena maso
  • kupweteka kumtunda chakumanja kwam'mimba
  • kutopa kwambiri
  • kutuluka mwachilendo kapena kuphwanya
  • kusowa mphamvu
  • kukhumudwa m'mimba
  • kusowa chilakolako
  • zizindikiro ngati chimfine
  • kukomoka kapena kupweteka kwakuthwa
  • kupweteka pachifuwa

Bicalutamide imatha kubweretsa zovuta zina. Itanani dokotala wanu ngati muli ndi zovuta zina mukamamwa mankhwalawa.


Mukakumana ndi zovuta zina, inu kapena adokotala mutha kutumiza lipoti ku pulogalamu ya Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting pa intaneti (http://www.fda.gov/Safety/MedWatch) kapena pafoni ( 1-800-332-1088).

Sungani mankhwala awa mu chidebe chomwe chidabwera, chatsekedwa mwamphamvu, komanso chosafikira ana. Zisungeni kutentha ndi kutali ndi kutentha kwambiri ndi chinyezi (osati kubafa).

Ndikofunika kuti mankhwala onse asamawonekere komanso kuti ana asamafikire ngati muli zidebe zambiri (monga mapiritsi a mlungu ndi mlungu ndi omwe amatsikira m'maso, mafuta, zigamba, ndi opumira) sizolimbana ndi ana ndipo ana aang'ono amatha kuzitsegula mosavuta. Pofuna kuteteza ana ang'ono kuti asatenge poyizoni, nthawi zonse tsekani zipewa zachitetezo ndikuyika mankhwalawo pamalo otetezeka - omwe ali pamwamba ndi kutali komanso osawonekera ndi kufikira. http://www.upandaway.org

Mankhwala osafunikira ayenera kutayidwa munjira zapadera zowonetsetsa kuti ziweto, ana, ndi anthu ena sangamwe. Komabe, simuyenera kuthira mankhwalawa mchimbudzi. M'malo mwake, njira yabwino yoperekera mankhwala anu ndikadongosolo lobwezera mankhwala. Lankhulani ndi wamankhwala wanu kapena lemberani dipatimenti yakunyumba / yobwezeretsanso kwanuko kuti muphunzire zamapulogalamu obwezeretsanso mdera lanu. Onani tsamba la FDA's Disposal of Medicines webusayiti (http://goo.gl/c4Rm4p) kuti mumve zambiri ngati mulibe pulogalamu yobwezera.

Mukadwala mopitirira muyeso, itanani foni yothandizira poyizoni pa 1-800-222-1222. Zambiri zimapezekanso pa intaneti pa https://www.poisonhelp.org/help. Ngati wozunzidwayo wagwa, watenga khunyu, akuvutika kupuma, kapena sangathe kudzutsidwa, nthawi yomweyo itanani anthu azadzidzidzi ku 911.

Sungani maimidwe onse ndi dokotala wanu ndi labotale. Dokotala wanu amalamula mayeso ena a labu kuti muwone momwe thupi lanu limayankhira bicalutamide.

Musalole kuti aliyense azimwa mankhwala anu. Funsani wamankhwala wanu mafunso aliwonse omwe muli nawo okhudzana ndi kudzaza mankhwala anu.

Ndikofunika kuti musunge mndandanda wamankhwala onse omwe mumalandira komanso osalembetsa (owerengera) omwe mukumwa, komanso zinthu zilizonse monga mavitamini, michere, kapena zakudya zina. Muyenera kubwera nawo pamndandandawu nthawi iliyonse mukapita kukaonana ndi dokotala kapena ngati mwalandiridwa kuchipatala. Ndikofunikanso kuthana nanu pakagwa mwadzidzidzi.

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Idasinthidwa Komaliza - 01/15/2018

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