Tranexamic acid: ndi chiyani, ndi chiyani komanso momwe mungagwiritsire ntchito
Zamkati
Tranexamic acid ndi chinthu chomwe chimalepheretsa enzyme yotchedwa plasminogen, yomwe nthawi zambiri imamangirira kuundana kuti iwawononge ndikuwateteza kuti asapangitse thrombosis, mwachitsanzo. Komabe, mwa anthu omwe ali ndi matenda omwe amachititsa kuti magazi azikhala ochepa kwambiri, plasminogen imathandizanso kuti magazi asapangike pakucheka, mwachitsanzo, kupangitsa kuti kukhale kovuta kuti magazi asiye kutuluka.
Kuphatikiza apo, mankhwalawa amawonekeranso kuti amateteza kupanga melanin mwachizolowezi, chifukwa chake, atha kugwiritsidwa ntchito kuchepetsa zipsera zakhungu, makamaka pankhani ya melasma.
Chifukwa chochita zinthu ziwiri, mankhwalawa amatha kupezeka ngati mapiritsi, kupewa magazi, kapena kirimu, kuti athandizire kuchepetsa mabala. Itha kugwiritsidwanso ntchito ngati jakisoni kuchipatala, kukonza zadzidzidzi zokhudzana ndi kutaya magazi kwambiri.
Ndi chiyani
Izi zimasonyezedwa kuti:
- Kuchepetsa chiopsezo chotaya magazi nthawi ya opaleshoni;
- Pewani melasmas ndi mawanga akuda pakhungu;
- Samalani ndi kutaya magazi komwe kumakhudzana ndi fibrinolysis yambiri.
Kugwiritsa ntchito mankhwalawa ngati mapiritsi kuti athetse kapena kupewa kutuluka kwa magazi kuyenera kuchitika kokha pambuyo povomereza kwa dokotala.
Momwe mungagwiritsire ntchito
Mlingo ndi nthawi yogwiritsira ntchito mankhwalawa ziyenera kutsogozedwa ndi dokotala nthawi zonse, komabe zisonyezo zake ndi izi:
- Chitani kapena pewani kutuluka magazi kwa ana: tengani 10 mpaka 25 mg / kg, kawiri kapena katatu patsiku;
- Samalani kapena pewani kutuluka magazi mwa akulu1 mpaka 1.5 magalamu, kawiri kapena kanayi patsiku, kwa masiku atatu. Kapena 15 mpaka 25 mg / tsiku ngati mankhwalawa atenga masiku opitilira atatu;
- Patsani khungu mawanga akhungu: gwiritsani zonona zomwe zimakhala pakati pa 0,4% ndi 4% ndikuzigwiritsa ntchito kuti muchepetse. Pakani zodzitetezera ku dzuwa masana.
Mlingo wa mapiritsiwo ukhoza kukhala wokwanira, ndi dokotala, malinga ndi mbiri ya wodwalayo, kugwiritsa ntchito mankhwala ena ndi zotsatira zake.
Zotsatira zoyipa
Zotsatira zoyipa kwambiri zimaphatikizapo kunyoza, kusanza, kutsegula m'mimba komanso kuchepa kwa magazi.
Yemwe sayenera kugwiritsa ntchito
Tranexamic acid sayenera kugwiritsidwa ntchito kwa anthu omwe ali ndi hemophilia akuchiritsidwa ndi mankhwala ena, kwa odwala omwe ali ndi intravascular coagulation kapena kupezeka kwa magazi mkodzo. Kuphatikiza apo, iyeneranso kupeŵedwa chifukwa cha maopaleshoni a thoracic kapena m'mimba, popeza pali chiopsezo chachikulu chovulazidwa.