Mlembi: Judy Howell
Tsiku La Chilengedwe: 4 Kulayi 2021
Sinthani Tsiku: 15 Novembala 2024
Anonim
Aspergillus fumigatus VS Aspergillus flavus | Microbiology
Kanema: Aspergillus fumigatus VS Aspergillus flavus | Microbiology

Zamkati

Chidule

Aspergillus fumigatus ndi mtundu wa bowa. Amapezeka m'chilengedwe chonse, kuphatikiza m'nthaka, mbewu, ndi fumbi la m'nyumba. Bowa amathanso kupanga ma spores obwera m'mlengalenga otchedwa conidia.

Anthu ambiri amatha kupumira ma spores ambiri tsiku lililonse. Mwa munthu wathanzi, chitetezo chamthupi nthawi zambiri chimachotsa m'thupi popanda vuto. Komabe, kwa anthu ena, kutulutsa mpweya A. fumigatus, spores imatha kubweretsa matenda omwe angakhale oopsa kwambiri.

Ndani ali pachiwopsezo?

Muli pachiwopsezo chachikulu chodwala A. fumigatus ngati:

  • khalani ndi chitetezo chamthupi chofooka, chomwe chingaphatikizepo ngati mukumwa mankhwala osokoneza bongo, muli ndi khansa inayake yamagazi, kapena mukudwala AIDS
  • ali ndi vuto lamapapu, monga mphumu kapena cystic fibrosis
  • khalani ndi kuchuluka kwama cell oyera oyera, omwe amatha kuchitika ngati mukumwa mankhwala a chemotherapy, ngati muli ndi leukemia, kapena mutadulidwa
  • akhala pa chithandizo cha corticosteroid cha nthawi yayitali
  • akuchira ku matenda apakhungu a chimfine

Matenda omwe amayambitsidwa ndi A. fumigatus

Matenda omwe amayamba chifukwa cha Aspergillus Mitundu ya bowa imatchedwa aspergillosis.


A. fumigatus ndi chimodzi mwazomwe zimayambitsa aspergillosis. Ndikofunika kuzindikira kuti zina Aspergillus Mitundu imatha kupatsiranso anthu. Mitunduyi ingaphatikizepo A. flavus, A. niger, ndi A. terreus.

Pali mitundu ingapo ya aspergillosis, kuphatikiza:

Matupi bronchopulmonary aspergillosis

Vutoli limakhala losavomerezeka ndi Aspergillus spores. Izi zimatha kubweretsa kuwonongeka mumlengalenga ndi m'mapapu anu. Nthawi zambiri amapezeka mwa anthu omwe ali ndi matenda monga asthma ndi cystic fibrosis.

Zizindikiro zimatha kuphatikiza:

  • malungo
  • kufooka
  • kumva kudwala kapena kusasangalala
  • kukhosomola mapulagi abulauni a ntchofu kapena ntchofu zokhala ndi magazi

Anthu omwe ali ndi mphumu amathanso kuzindikira kuti zizindikiro zawo za mphumu zimayamba kukulira. Izi zitha kuphatikizira kuwonjezeka kwa kupuma pang'ono kapena kupuma.

Matenda a aspergillosis

Matenda a m'mapapo mwanga aspergillosis amakula pang'onopang'ono. Zitha kuchitika kwa anthu omwe ali ndi matenda am'mapapo omwe amachititsa kuti mpweya uzikhala m'mapapu. Zitsanzo za zinthu ngati izi ndi chifuwa chachikulu ndi chifuwa chachikulu.


Matenda a aspergillosis amatha kuwonekera m'njira zingapo, zomwe zingaphatikizepo:

  • madontho ang'onoang'ono a Aspergillus matenda m'mapapu, otchedwa ma nodule
  • Mipira yolumikizidwa ya bowa mkati mwa mapapo, yotchedwa aspergillomas (izi nthawi zina zimatha kuyambitsa zovuta monga kutuluka magazi m'mapapu)
  • Matenda ofala kwambiri am'mapapo angapo, omwe amatha kukhala ndi aspergillomas

Mukasiyidwa osalandiridwa, kufalikira kwa matenda kumatha kubweretsa kukulira ndi mabala am'mapapo, zomwe zitha kubweretsa kutayika kwa mapapo.

Anthu omwe ali ndi matenda am'mapapo a aspergillosis amatha kukhala ndi izi:

  • malungo
  • chifuwa, chomwe chingaphatikizepo kutsokomola magazi
  • kupuma movutikira
  • kumva kutopa
  • kumva kudwala kapena kusasangalala
  • kuonda kosadziwika
  • thukuta usiku

Aspergillosis yovuta

Aspergillosis yovuta kwambiri ndiyo mitundu yoopsa kwambiri ya aspergillosis ndipo imatha kupha ngati singachiritsidwe. Zimachitika matenda opatsirana a aspergillosis amayamba m'mapapu ndikufalikira mbali zina za thupi lanu, monga khungu, ubongo, kapena impso. Aspergillosis wowopsa amapezeka mwa anthu okha omwe ali ndi chitetezo chamthupi chofooka kwambiri.


Zizindikiro za kuwopsa kwa aspergillosis zitha kuphatikiza:

  • malungo
  • chifuwa, chomwe chingaphatikizepo kutsokomola magazi
  • kupuma movutikira
  • kupweteka pachifuwa, komwe kumatha kuipiraipira mukamapuma kwambiri

Matendawa akamafalikira kunja kwa mapapo, zizindikilo zimatha kudalira gawo liti la thupi lomwe lakhudzidwa, koma limaphatikizaponso:

  • mutu
  • maso otupa
  • m'mphuno
  • kupweteka pamodzi
  • zotupa pakhungu
  • zovuta ndi kuyankhula
  • chisokonezo
  • kugwidwa

Chithandizo cha matenda a A. fumigatus

An A. fumigatus Matendawa amatha kukhala ovuta kuwazindikira chifukwa nthawi zambiri zizindikilozi zimafanana ndimapapu ena monga chifuwa chachikulu.

Kuphatikiza apo, kuwunika pang'ono kwa sputum kapena zitsanzo zamatenda kumatha kukhala kosadziwika chifukwa Aspergillus Mitundu imatha kuwoneka yofanana kwambiri ndi mitundu ina ya mafangayi ikawonedwa ndi microscope.

Njira zowunikira za Aspergillus zingaphatikizepo:

  • chikhalidwe cha sputum sampuli kuti adziwe Aspergillus kukula
  • X-ray pachifuwa kuti ayang'ane zizindikiro za matenda, monga aspergillomas
  • kuyesa magazi kuti muwone ngati ma antibodies ku Aspergillus amapezeka m'magazi anu
  • polymerase chain reaction (PCR), yomwe ndi njira yamagulu yomwe ingagwiritsidwe ntchito kuzindikira Aspergillus Mitundu yochokera ku sputum kapena minofu
  • amayesa kuti apeze gawo limodzi la khoma la fungal la Aspergillus ndi mitundu ina ya mafangasi (mayeso a anti-galactomannan antigen ndi kuyesa kwa beta-d-glucan)
  • kuyezetsa khungu kapena magazi kutsimikizira kuti pali zovuta zina Aspergillus spores

Matenda a bronchopulmonary aspergillosis amatha kuchiritsidwa ndi oral corticosteroids. Nthawi zina mumatenga ma corticosteroids osakanikirana ndi mankhwala antifungal monga itraconazole.

Matenda a m'mapapo a aspergillosis omwe amakhala ndi ma nodule kapena ma aspergillomas osagwirizana angafunike chithandizo. Izi ndizowona makamaka ngati mulibe zizindikiro zilizonse. Mitunduyi iyenera kuyang'aniridwa nthawi zonse kuti iwonetsetse kuti sizikupita patsogolo.

Mankhwala oletsa antifungal amagwiritsidwa ntchito pochiza matenda oopsa am'mapapo mwanga aspergillosis, komanso aspergillosis wowopsa. Zitsanzo za mankhwala omwe angakhale othandiza ndi voriconazole, itraconazole, ndi amphotericin B.

Posachedwa, ofufuza awona kulimbana kwa A. fumigatus mankhwala azole antifungal. Izi zimaphatikizapo mankhwala monga voriconazole ndi intraconazole. Pakakhala kuti matendawa sagwirizana ndi mankhwala a azole, ma antifungal ena monga amphotericin B adzafunika kugwiritsidwa ntchito pochiza.

Kukulitsa kapena kuchotsa opaleshoni ndichinthu chosankha ngati aspergillomas ikuyambitsa zovuta monga kutuluka magazi m'mapapu.

Kupewa matenda

A. fumigatus ndi zina Aspergillus Mitundu ilipo m'chilengedwe chonse. Pazifukwa izi, zitha kukhala zovuta kupewa kuwonekera. Komabe, ngati muli m'gulu lomwe lili pachiwopsezo, pali zina zomwe mungachite kuti muchepetse matenda.

Pewani zinthu zomwe zingakugwirizanitseni Aspergillus zamoyo.

Zitsanzo zake ndi monga kulima dimba, kugwira ntchito pabwalo, kapena kuyendera malo omanga. Ngati mukuyenera kukhala m'malo awa, onetsetsani kuvala mathalauza ndi mikono yayitali. Valani magolovesi ngati mukugwira nthaka kapena manyowa. Makina opumira N95 atha kukuthandizani ngati mungapezeke m'malo okhala ndi fumbi kwambiri.

Tengani mankhwala oletsa kupewera mafungal

Ngati mwangomaliza kumene kuchitidwa ngati kumuika thupi, dotolo wanu akhoza kukupatsani mankhwala othandizira kuti musatenge matenda.

Kuyesedwa kwa Aspergillus zamoyo

Ngati muli pagulu lomwe lili pachiwopsezo, kuyesa nthawi ndi nthawi Aspergillus zingathandize kuzindikira matendawa asanayambe. Ngati matenda amapezeka, inu ndi dokotala mutha kugwira ntchito limodzi kuti mupange dongosolo lamankhwala.

Kutenga

Aspergillus fumigatus zingayambitse matenda oopsa kwa anthu omwe ali ndi chitetezo chamthupi chofooka kapena mapapu. Matenda omwe amayamba chifukwa cha A. fumigatus ndi zina Aspergillus mitundu amatchedwa aspergillosis.

Maganizo a aspergillosis amatengera zinthu zingapo, kuphatikiza:

  • mtundu wa matenda
  • malo opatsirana
  • thupi lanu lonse

Kuzindikira mwachangu chithandizo cha aspergillosis kumathandizira kukonza mawonekedwe.

Ngati muli m'gulu lomwe lili pachiwopsezo chokhala ndi aspergillosis, lankhulani ndi dokotala wanu. Amatha kukuwuzani njira zomwe mungapewere kutenga kachiromboka.

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