Collagenosis: ndi chiyani, zimayambitsa zazikulu ndi momwe angachiritsire

Zamkati

• 1. Lupus
• 2. Scleroderma
• 3. Matenda a Sjogren
• 4. Dermatomyositis
• Momwe mungatsimikizire matendawa
• Momwe mungachiritse collagenosis
• Chifukwa chiyani zimachitika

Collagenosis, yomwe imadziwikanso kuti matenda a collagen, imadziwika ndi gulu la matenda omwe amadzimangirira okha komanso otupa omwe amawononga minofu yolumikizana ya thupi, yomwe ndi minofu yopangidwa ndi ulusi, monga collagen, ndipo imayang'anira ntchito monga kudzaza malo pakati ziwalo, zimapereka chithandizo, kuwonjezera pakuthandizira kuteteza thupi.

Kusintha komwe kumachitika chifukwa cha collagenosis kumatha kukhudza ziwalo ndi machitidwe osiyanasiyana mthupi, monga khungu, mapapo, mitsempha yamagazi ndi zotupa zam'mimba, mwachitsanzo, ndikupanga zizindikiritso za dermatological ndi rheumatological, zomwe zimaphatikizira kupweteka kwa mafupa, zotupa pakhungu, kusintha kwa khungu , kuzungulira kwa magazi kapena pakamwa pouma ndi maso.

Ena mwa collagenoses akulu ndi matenda monga:

1. Lupus

Ndiwo matenda amthupi okhaokha, omwe amawononga ziwalo ndi maselo chifukwa cha zochita za autoantibodies, ndipo amapezeka kwambiri mwa atsikana, ngakhale atha kupezeka mwa aliyense. Zomwe zimayambitsa sizidziwikiratu, ndipo matendawa amayamba pang'onopang'ono komanso mosalekeza, ali ndi zizindikilo zomwe zimatha kukhala zofewa mpaka zovuta, zomwe zimasiyanasiyana malinga ndi munthu.

Zizindikiro ndi zizindikilo: lupus imatha kuyambitsa mawonetseredwe azachipatala osiyanasiyana, kuyambira komwe kudzafalikiridwa mpaka kufalikira mthupi lonse, kuphatikiza zolakwika pakhungu, zilonda zam'kamwa, nyamakazi, kusokonezeka kwa impso, kusokonezeka kwa magazi, kutupa kwa mapapo ndi mtima.

Phunzirani zambiri za zomwe zili komanso momwe mungadziwire lupus.

2. Scleroderma

Ndi matenda omwe amachititsa kuti michere ya collagen ipezeke mthupi, chifukwa chomwe sichikudziwika, ndipo imakhudza kwambiri khungu ndi zimfundo, ndipo imakhudzanso magazi ndi ziwalo zina zamkati, monga mapapo, mtima, impso ndi mundawo m'mimba.

Zizindikiro ndi zizindikilo: Nthawi zambiri khungu limakula, lomwe limakhala lolimba, lowala komanso limavutikira kuzungulira kwa magazi, lomwe limafota pang'onopang'ono komanso mosalekeza. Ikafika ziwalo zamkati, momwe imafalikira, imatha kupangitsa kupuma movutikira, kusintha kwa m'mimba, kuphatikiza zovuta za mtima ndi impso, mwachitsanzo.

Mvetsetsani bwino zizindikilo za mitundu yayikulu ya scleroderma ndi momwe mungachiritse.

3. Matenda a Sjogren

Ndi nthenda ina yodziyimira yokha, yomwe imadziwika ndikulowerera kwamaselo oteteza kumatenda m'thupi, zomwe zimalepheretsa kutulutsa katulutsidwe ndimatenda am'mimba ndi amate. Matendawa amapezeka kwambiri mwa amayi azaka zapakati, koma amatha kupezeka mwa aliyense, ndipo amatha kuwonekera payokha kapena atatsagana ndi matenda monga nyamakazi, lupus, scleroderma, vasculitis kapena hepatitis, mwachitsanzo.

Zizindikiro ndi zizindikilo: pakamwa pouma ndi maso ndizizindikiro zazikulu, zomwe zitha kukulira pang'onopang'ono komanso pang'onopang'ono, ndipo zimayambitsa kufiira, kuyaka komanso kumverera kwa mchenga m'maso kapena kuvutika kumeza, kuyankhula, kuwola kwa mano komanso kumva kutentha mkamwa. Zizindikiro m'mbali zina za thupi ndizosowa kwambiri, koma zimatha kuphatikizira kutopa, kutentha thupi komanso kupweteka kwaminyewa ndi minofu, mwachitsanzo.

Kumvetsetsa bwino momwe mungadziwire komanso kudziwa matenda a Sjogren.

4. Dermatomyositis

Imeneyi ndi nthenda yomwe imayambitsa komanso kusokoneza minofu ndi khungu. Zimakhudza minofu yokha, imadziwikanso kuti polymyositis. Choyambitsa chake sichikudziwika, ndipo chitha kuchitika mwa anthu azaka zonse.

Zizindikiro ndi zizindikilo: ndizofala kukhala ndi kufooka kwa minofu, kofala kwambiri mu thunthu, kuletsa kuyenda kwa mikono ndi mafupa a chiuno, monga kupesa tsitsi kapena kukhala / kuimirira. Komabe, minofu iliyonse imatha kufikiridwa, ndikupangitsa zovuta kumeza, kusuntha khosi, kuyenda kapena kupuma, mwachitsanzo. Zilonda zapakhungu zimaphatikizapo mawanga ofiira kapena ofiira komanso kuwuluka komwe kumatha kuwonjezeka ndi dzuwa.

Pezani zambiri zamomwe mungadziwire ndi kuchizira dermatomyositis.

Momwe mungatsimikizire matendawa

Pofuna kudziwa collagenosis, kuphatikiza pakuwunika kwamankhwala, adotolo amatha kuyitanitsa kuyesa magazi komwe kumazindikira kutupa ndi ma antibodies omwe amapezeka m'matendawa, monga FAN, Mi-2, SRP, Jo-1, Ro / SS-A kapena La / SS- B, mwachitsanzo. Ma biopsies kapena kusanthula kwamatenda otupa kungakhale kofunikira.

Momwe mungachiritse collagenosis

Chithandizo cha collagen, komanso matenda aliwonse omwe amadzichotsera okha, zimadalira mtundu wake komanso kuuma kwake, ndipo ayenera kutsogozedwa ndi rheumatologist kapena dermatologist. Nthawi zambiri, zimaphatikizapo kugwiritsa ntchito corticosteroids, monga Prednisone kapena Prednisolone, kuphatikiza ma immunosuppressants ena kapena ma chitetezo a chitetezo, monga Azathioprine, Methotrexate, Cyclosporine kapena Rituximab, monga njira yothetsera chitetezo chokwanira ndikuchepetsa zovuta zake thupi.

Kuphatikiza apo, njira zina monga kuteteza dzuwa kuteteza zotupa pakhungu, komanso madontho opangira diso kapena malovu ochepetsa kuuma kwa maso ndi mkamwa, zitha kukhala njira zina zochepetsera zizindikilo.

Collagenosis ilibe mankhwala, komabe sayansi yafuna kupeza njira zochiritsira zamakono, kutengera chitetezo chamthupi ndi immunotherapy, kuti matendawa athe kuwongoleredwa moyenera.

Chifukwa chiyani zimachitika

Palibenso chifukwa chomveka chobweretsera gulu la matenda omwe amayambitsa collagenosis. Ngakhale ndizokhudzana ndi kulakwitsa komanso kupititsa patsogolo chitetezo cha mthupi, sizikudziwika chomwe chimayambitsa izi.

Ndizotheka kuti pali njira zamtundu komanso zachilengedwe, monga moyo ndi kadyedwe, chifukwa choyambitsa matendawa, komabe, sayansi ikufunikirabe kuzindikira kukayikiraku popitiliza maphunziro.