Sclerosing cholangitis: ndi chiyani, zizindikiro ndi chithandizo

Zamkati

• Zizindikiro za sclerosing cholangitis
• Zoyambitsa zazikulu
• Momwe matendawa amapangidwira
• Chithandizo cha sclerosing cholangitis

Sclerosing cholangitis ndi matenda osowa kwambiri omwe amapezeka mwa amuna omwe amadziwika kuti amatenga chiwindi chifukwa cha kutupa ndi fibrosis yoyambitsidwa ndi kuchepa kwa njira zomwe bile imadutsa, yomwe ndi chinthu chofunikira kwambiri pakudya m'mimba, komwe kumatha kubweretsa, nthawi zina, ku mawonekedwe azizindikiro zina, monga kutopa kwambiri, khungu lachikaso ndi maso komanso kufooka kwa minofu.

Zomwe zimayambitsa cholangitis sizidziwikiratu, komabe amakhulupirira kuti mwina zimakhudzana ndi zinthu zomwe zimayambitsa autoimmune zomwe zingayambitse kutupa kwaminyewa ya bile. Malinga ndi chiyambi, sclerosing cholangitis imatha kugawidwa m'magulu awiri akulu:

• Pulayimale sclerosing cholangitis, momwe kusinthaku kudayambika m'mabande a bile;
• Sekondale sclerosing cholangitis, momwe kusinthaku ndi zotsatira za kusintha kwina, monga chotupa kapena zoopsa patsamba lino, mwachitsanzo.

Ndikofunikira kuti chiyambi cha cholangitis chizindikiridwe kuti chithandizo choyenera kwambiri chitha kuwonetsedwa, chifukwa chake, tikulimbikitsidwa kukaonana ndi dokotala kapena hepatologist kuti tiwonetse kuyesa ndi kuyesa kwa labotale komwe kumalola kuti matenda athe.

Zizindikiro za sclerosing cholangitis

Matenda ambiri a cholangitis samayambitsa kuwonekera kwa zizindikilo, ndipo kusintha kumeneku kumangopezeka pakuyesa kwa kujambula. Komabe, anthu ena amatha kukhala ndi zizindikilo, makamaka zikafika ku sclerosing cholangitis, komwe kumakhala bile yambiri mchiwindi. Chifukwa chake, zizindikilo zazikulu zomwe zikuwonetsa kuti cholangitis ndi izi:

• Kutopa kwambiri;
• Thupi loyabwa;
• Khungu lachikaso ndi maso;
• Pakhoza kukhala kuzizira ndi kupweteka m'mimba;
• Minofu kufooka;
• Kuwonda;
• Kukulitsa chiwindi;
• Kukula kwa nthata;
• Kutuluka kwa xanthomas, komwe ndi zotupa pakhungu lopangidwa ndi mafuta;
• Kuyabwa.

Nthawi zina, pangakhalenso kutsekula m'mimba, kupweteka m'mimba komanso kupezeka kwa magazi kapena ntchofu pampando. Pamaso pazizindikirozi, makamaka ngati zimachitika mobwerezabwereza kapena mosalekeza, ndikofunikira kukaonana ndi dokotala kapena hepatologist kuti kuyezetsa kuchitike ndikuyenera kulandira chithandizo choyenera.

Zoyambitsa zazikulu

Zomwe zimayambitsa sclerosing cholangitis sizinakhazikitsidwe bwino, komabe akukhulupirira kuti mwina chifukwa cha kusintha kwamasinthidwe amthupi kapena kukhala okhudzana ndi majini kapena matenda amtundu wa virus kapena mabakiteriya.

Kuphatikiza apo, akukhulupiliranso kuti sclerosing cholangitis imakhudzana ndi ulcerative colitis, momwe anthu omwe ali ndi matenda amtundu woterewa ali pachiwopsezo chachikulu chotenga cholangitis.

Momwe matendawa amapangidwira

Kuzindikira kwa sclerosing cholangitis kumapangidwa ndi dokotala kapena hepatologist kudzera pakuyesa kwa labotale ndi kulingalira. Nthawi zambiri, kuzindikira koyambirira kumachitika chifukwa cha mayeso omwe amawunika momwe chiwindi chimagwirira ntchito, ndikusintha kwa michere ya chiwindi, monga TGO ndi TGP, kuphatikiza pakukula kwa alkaline phosphatase ndi gamma-GT. Nthawi zina, adokotala angafunenso kuti agwiritse ntchito mapuloteni electrophoresis, momwe kuchuluka kwa gamma globulins, makamaka IgG, kumawonekeranso.

Pofuna kutsimikizira kuti ali ndi vutoli, adotolo atha kupempha kuti awonetse chiwindi komanso cholangiography, yomwe ndi mayeso owunika omwe amayesa kuwunika timabowo ta ndulu ndikuyang'ana njira yochokera ku ndulu yochokera pachiwindi kupita ku duodenum, kuti athe kuwona kusintha kulikonse. Mvetsetsani momwe cholangiography imachitikira.

Chithandizo cha sclerosing cholangitis

Chithandizo cha sclerosing cholangitis chimachitika molingana ndi kuuma kwa cholangitis ndipo cholinga chake ndikulimbikitsa kupumula kwa zizindikiro ndikupewa zovuta. Ndikofunikira kuti mankhwala ayambidwe patangopita nthawi yochepa kuti munthu adziwe matendawa kuti apewe kukula kwa matendawa ndikubweretsa zovuta zina monga chiwindi cha chiwindi, matenda oopsa komanso chiwindi.

Chifukwa chake, kugwiritsa ntchito mankhwala okhala ndi ursodeoxycholic acid, odziwika bwino ngati Ursacol, atha kuwonetsedwa ndi adotolo, kuwonjezera pa mankhwala a endoscopic kuti muchepetse kuchuluka kwa zotchinga ndikukonda kupita kwa bile. Pazovuta kwambiri za cholangitis, momwe sizikusintha pazizindikiro pogwiritsa ntchito mankhwala osokoneza bongo, kapena pamene zizindikilozo zibwereza, adotolo amalimbikitsa kuti apange chiwindi.