High cortisol: chomwe chingakhale, zizindikiro ndi momwe mungatsitsire

Zamkati

• Zoyambitsa zazikulu
• Zizindikiro zomwe zingachitike mthupi
• Momwe mungachepetse milingo ya cortisol
• Chifukwa chiyani mimba imawonjezera cortisol

High cortisol imayamba chifukwa chodya ma corticosteroids kwa masiku opitilira 15, kapena kuwonjezeka pakupanga kwa hormone iyi m'matope a adrenal, chifukwa chapanikizika kapena chotupa.

Vutoli likayikiridwa, chifukwa cha zovuta zoyipa za cortisol yochulukirapo, monga kunenepa, kuthamanga kwa magazi, matenda ashuga komanso kufooka kwa mafupa, dokotala akhoza kuyitanitsa mayeso a cortisol, poyeza magazi, mkodzo kapena malovu.

Kuwongolera kwa hormone iyi kumachitika ndikulimbitsa thupi komanso kudya zakudya zomwe zimathandizira kupsinjika ndi shuga wamagazi, monga zilazi, phazi, mazira, fulakesi ndi mkaka ndi zotumphukira, mwachitsanzo. Komabe, cortisol ikakhala yayikulu, chithandizo chamankhwala kapena opaleshoni, chotsogozedwa ndi endocrinologist, ndichofunikira.

Zoyambitsa zazikulu

Kugwiritsa ntchito mankhwala a corticosteroid, monga prednisone kapena dexamethasone, kwa masiku opitilira 15 ndiye mtundu wofala kwambiri wa cortisol wamagazi, koma zifukwa zina ndi izi:

• Kupsinjika kwakanthawi komanso kugona mokhazikika: atha kusiyanitsa kupanga kwa cortisol ndikupangitsa kuti iwonjezeke m'thupi;
• Kulephera kwa adrenal glands: amayambitsidwa ndi kupezeka kwa chotupa kapena kuchepa kwa maselo ake, komwe kumatha kupanga cortisol yochulukirapo;
• Chotupa chaubongo: imatha kulimbikitsa kutulutsa kwa cortisol ndimatenda a adrenal.

Kupsinjika nthawi zambiri kumabweretsa kusintha pang'ono pamiyeso ya cortisol, pomwe kuwonjezeka kwakukulu komanso kwakukulu kumachitika chifukwa cha kusintha kwamatenda a adrenal ndi ubongo.

Zizindikiro zomwe zingachitike mthupi

Ikapangidwa m'matope a adrenal, cortisol imatulutsidwa m'magazi kuti iwongolere momwe thupi limagwirira ntchito. Komabe, mopitirira muyeso, komanso kwakanthawi, zimatha kuyambitsa mavuto monga:

• Kuchulukitsa, kuzungulira m'chiuno ndi kuphulika, posungira kwamadzi, ndikugawikanso mafuta amthupi;
• Matenda ashuga komanso kuchuluka kwa shuga m'magazi, zolimbikitsa chiwindi kupanga shuga;
• Kufooka kwa mafupa, pochepetsa kuyamwa kwa calcium ndi thupi ndikuchepetsa collagen;
• Kuchuluka kwa nkhawa, kukwiya komanso kukhumudwa, mwa kuchititsa kuti adrenaline amasulidwe komanso kuchitapo kanthu mwachindunji muubongo;
• Cholesterol wokwera, powonjezera kupanga mafuta ndi chiwindi ndikuwamasulira;
• Kuchepetsa minofu ndi kufooka, chifukwa amachepetsa kupanga mapuloteni ndikutsitsa mapuloteni m'matumba;
• Kuthamanga, poyambitsa kusungidwa kwa sodium ndi zakumwa, ndikuwonjezera kutulutsa kwa adrenaline;
• Kuchepetsa chitetezo chamthupi, poletsa kutupa ndi chitetezo chamthupi;
• Kuchuluka kwa mahomoni achimuna pa thupi, lomwe mwa amayi limatha kuyambitsa zizindikilo zosafunikira, monga tsitsi lopyola muyeso, kukulitsa mawu ndi kutayika kwa tsitsi;
• Kusintha kwa msambo komanso kuvutika kutenga pakati, pochepetsa mahomoni achikazi;
• Kusakhazikika pakhungu, mabala owonjezeka, zolakwika pakhungu ndi zotambalala, pochepetsa collagen ndikuchepetsa mphamvu yakuchiritsa thupi.

Dzinalo la kusintha kumeneku kumadza chifukwa cha kuchuluka kwakanthawi kwa cortisol ndi matenda a Cushing's. Pomwe matendawa kapena kuchuluka kwa cortisol akukayikiridwa, dokotala kapena endocrinologist atha kuyitanitsa mayeso amwazi, mkodzo kapena malovu, omwe akuwonetsa kuchuluka kwa hormone iyi mthupi.

Ngati mayeserowa ndi ofunika kwambiri, adokotala adzafufuza chomwe chimayambitsa cortisol yochulukirapo, kuwunika kwamankhwala, komanso kudzera mu tomography kapena MRI, pamimba ndi ubongo, PET kapena scintigraphy.

Dziwani zambiri za momwe mayeso a cortisol amachitikira.

Momwe mungachepetse milingo ya cortisol

Popeza cortisol imalumikizidwa kwambiri ndi momwe zimakhalira, njira yabwino yoyendetsera cortisol ndikuchepetsa kupsinjika ndi nkhawa, ndimankhwala amisala komanso nthawi yopuma. Kuphatikiza apo, kuchita masewera olimbitsa thupi komanso kudya zakudya zokhala ndi zomanga thupi ndi potaziyamu, monga mazira, mkaka ndi zopangidwa ndi mkaka, nsomba, oats, maamondi, mabokosi, chia ndi nthonje, zitha kuthandizanso.

Pakadali pano, kuchuluka kwa cortisol kumachitika chifukwa chogwiritsa ntchito corticosteroids, imayenera kuchotsedwa pang'onopang'ono, kwa masiku angapo, motsogozedwa ndi dokotala kapena endocrinologist.

Chifukwa chakuchulukirachulukira, cortisol imakhala yayikulu kwambiri, monga chotupa, mankhwalawa amachitika pogwiritsa ntchito mankhwala ochepetsa kuchuluka kwa mahomoni, monga metyrapone, aminoglutetimide, ndi opaleshoni yochotsa chotupacho , yomwe idzasankhidwa ndikukonzedwa pakati pa wodwalayo, endocrinologist ndi dotolo.

Phunzirani momwe mungapangire mankhwala achilengedwe omwe amathandizira kuwongolera cortisol.

Chifukwa chiyani mimba imawonjezera cortisol

Mlingo waukulu wa cortisol umakhala wofala pakakhala ndi pakati, makamaka m'masabata omaliza ali ndi pakati, popeza kuti placenta imatulutsa timadzi tomwe timadziwika kuti CRH, timene timayambitsa kaphatikizidwe ka cortisol, ndikuwonjezera kuchuluka kwake mthupi la mayi wapakati.

Komabe, mosiyana ndi zomwe zimachitika kunja kwa mimba, milingo yayikulu ya cortisol panthawi yoyembekezera sikuwoneka kuti ikukhudza thanzi la mayi kapena mwana, chifukwa ndikofunikira kuti akhalebe ndi pakati komanso akuwoneka ngati akuthandiza kukula kwa ubongo ndi mapapo. Pachifukwa ichi, makanda obadwa masiku asanakwane amakhala ndi vuto la kupuma. Chifukwa chake, mayi wapakati akakhala pachiwopsezo chachikulu chobadwa msanga, sizachilendo kwa oyembekezera kuti alangize za kupangidwa kwa ma corticosteroids, kuti athandizire pakukula kwa ziwalo za mwana.

Zovuta za cortisol, monga Cushing's syndrome, ndizosowa kwambiri panthawi yapakati komanso ngakhale pambuyo pobereka, popeza milingo ya cortisol imayamba kugwera pamakhalidwe oyenera mwana akabadwa.