Zomwe Muyenera Kudziwa Zokhudza DHT ndi Kutayika Kwa Tsitsi
Zamkati
- Kodi DHT ndi chiyani?
- Kodi DHT imachita chiyani?
- Kukhala ndi DHT yochepa kwambiri
- Chifukwa chomwe DHT imakhudzira anthu mosiyanasiyana
- Kulumikizana kwa DHT ndi balding
- DHT vs. testosterone
- Momwe mungachepetse DHT
- Kumaliza ndalama
- Minoxidil
- Zamgululi
- Makungwa a Pygeum
- Mafuta a dzungu
- Kafeini
- Vitamini B-12 ndi B-6
- Zotsatira zoyipa za ma DHT blockers
- Zina zomwe zimayambitsa tsitsi
- Alopecia areata
- Ndere zamatsenga
- Makhalidwe a chithokomiro
- Matenda achilendo
- Matenda a khungu
- Tsitsi la bamboo
- Tengera kwina
Kodi DHT ndi chiyani?
Kujambula amuna, komwe kumatchedwanso androgenic alopecia, ndichimodzi mwazifukwa zomwe amuna amasiya tsitsi akamakalamba.
Amayi amathanso kukumana ndi tsitsi lotere, koma ndizochepa kwambiri. Pafupifupi azimayi 30 miliyoni ku United States ali ndi tsitsi lotere poyerekeza ndi amuna 50 miliyoni.
Mahomoni ogonana mthupi amakhulupirira kuti ndi omwe amachititsa chidwi kwambiri pakutha kwa tsitsi la amuna.
Dihydrotestosterone (DHT) ndi androgen. Anrogen ndi mahomoni ogonana omwe amathandizira kukulitsa zomwe zimaganiziridwa ngati zikhalidwe za "amuna" zogonana, monga tsitsi la thupi. Komanso zimatha kukupangitsani kuti muzimeta tsitsi mwachangu komanso koyambirira.
Pali mankhwala omwe amatanthauza kuti achepetse kuyambika kwa dazi la amuna potengera DHT. Tiyeni tikambirane momwe DHT imagwirira ntchito, momwe DHT imagwirizanirana ndi tsitsi lanu komanso testosterone, ndi zomwe mungachite kuti muleke, kapena kuchedwetsa, kusamba kwamitundu ya amuna.
Kodi DHT imachita chiyani?
DHT imachokera ku testosterone. Testosterone ndi hormone yomwe imapezeka mwa amuna ndi akazi. Ndi DHT ndi ma androgens, kapena mahomoni omwe amathandizira kuti amuna azigonana mukamatha msinkhu. Makhalidwe awa ndi awa:
- mawu akuya
- kuchuluka kwa tsitsi la thupi ndi minofu
- kukula kwa mbolo, zikopa, ndi machende pamene umuna umayamba
- zosintha momwe mafuta amasungidwa mthupi lanu
Mukamakula, testosterone ndi DHT zimakhala ndi maubwino ena ambiri mthupi lanu, monga kusunga minofu yanu yonse ndikulimbikitsa thanzi ndikugonana.
Amuna nthawi zambiri amakhala ndi testosterone m'matupi awo. Pafupifupi 10% ya testosterone mwa achikulire onse amasinthidwa kukhala DHT mothandizidwa ndi enzyme yotchedwa 5-alpha reductase (5-AR).
Mukangoyenda momasuka m'magazi anu, DHT imatha kulumikizana ndi zolandirira pamutu pamutu panu, kuwapangitsa kuchepa ndikukhala osakwanitsa kuthandizira mutu wathanzi.
Ndipo kuthekera kwa DHT kovulaza kumapitilira tsitsi lanu. Kafukufuku walumikiza DHT, makamaka milingo yayikulu modabwitsa, ndi:
- kuchiritsa pang'onopang'ono pakhungu pambuyo povulala
- kukulitsa prostate
- khansa ya prostate
- mitima matenda
Kukhala ndi DHT yochepa kwambiri
Kuchuluka kwa DHT kumatha kukulitsa chiopsezo pazinthu zina, koma kukhala ndi DHT yocheperako kumathanso kubweretsa zovuta pakukula kwanu pakugonana mukamatha msinkhu.
Kutsika kwa DHT kumatha kuyambitsa kuchedwa kwa kutha msinkhu kwa amuna kapena akazi onse. Kupanda kutero, kutsika kwa DHT sikuwoneka kuti kumakhudza kwambiri amayi, koma mwa amuna, kutsika kwa DHT kumatha kuyambitsa:
- Kukula kwakanthawi kapena kosakwanira kwa ziwalo zogonana, monga mbolo kapena machende
- kusintha kwamagawa amthupi, kuchititsa zinthu monga gynecomastia
- kuonjezera chiopsezo chotenga zotupa za prostate zamphamvu
Chifukwa chomwe DHT imakhudzira anthu mosiyanasiyana
Kutulutsa kwanu pakutha kwa tsitsi ndi chibadwa, kutanthauza kuti zidaperekedwera m'banja lanu.
Mwachitsanzo, ngati ndinu wamwamuna ndipo abambo anu amakumana ndi malembedwe achimuna, ndizotheka kuti mudzawonetsanso mawonekedwe owerengera mukamakalamba. Ngati mumakonda kale dazi la amuna, kuwonda kwa DHT kumawonekera kwambiri.
Kukula ndi mawonekedwe amutu wanu zitha kuthandizanso kuti DHT ichepetse thupi lanu mwachangu.
Kulumikizana kwa DHT ndi balding
Tsitsi paliponse pathupi lanu limatuluka pansi pake pakhungu lanu lotchedwa ma follicles, omwe amakhala makapisozi ang'onoang'ono omwe ali ndi chingwe chimodzi cha tsitsi.
Tsitsi mkati mwa follicle nthawi zambiri limadutsa pakukula komwe kumatenga pafupifupi zaka ziwiri kapena zisanu ndi chimodzi. Ngakhale mutameta kapena kumeta tsitsi lanu, tsitsi lomwelo limatulukiranso kuchokera mumtsukowo kuchokera muzu wa tsitsilo womwe uli mkati mwake.
Kumapeto kwa kuzungulira uku, tsitsilo limalowera komwe kumatchedwa gawo lopumula lisanathe miyezi ingapo pambuyo pake. Kenako, chopondacho chimapanga tsitsi latsopano, ndipo kuzungulira kumayambiranso.
Mlingo wambiri wa ma androgens, kuphatikiza DHT, umatha kuchepetsa tsitsi lanu komanso kufupikitsa kuzungulira uku, ndikupangitsa kuti tsitsi likule likuwoneka locheperako komanso lophwanyaphwanya, komanso kutuluka mwachangu. DHT itha kupangitsanso kuti zitenge nthawi yayitali kuti ma follicles anu amere tsitsi limodzi tsitsi lakale likagwa.
Anthu ena amakhala pachiwopsezo chotere ndi DHT pamutu wamutu potengera kusiyanasiyana kwa jini lawo la androgen receptor (AR). Androgen receptors ndi mapuloteni omwe amalola mahomoni ngati testosterone ndi DHT kuti azigwirizana nawo. Ntchito yomangayi imabweretsa njira zamtundu wa mahomoni monga kukula kwa tsitsi lathupi.
Koma kusiyanasiyana kwa jini ya AR kumatha kukulitsa chidwi cha androgen m'matumbo anu akumutu, zomwe zimakupangitsani kuti muzitha kutaya tsitsi la amuna.
DHT vs. testosterone
Testosterone ndiyo androgen yochuluka kwambiri komanso yogwira ntchito m'thupi lamwamuna. Imayambitsa zochitika zambiri zogonana komanso zolimbitsa thupi, kuphatikizapo:
- kuwongolera kuchuluka kwamahomoni a androgen mthupi lonse
- kuyang'anira kupanga umuna
- kusunga mafupa ndi minofu
- kuthandiza kugawa mafuta mthupi lonse
- kuwongolera momwe mukumvera mumtima mwanu
DHT ndi mphukira ya testosterone. DHT imatenganso gawo pazochitika zina zofananira zogonana komanso njira zakuthupi monga testosterone, koma ndizolimba kwambiri. DHT imatha kulumikizana ndi cholandilira cha androgen nthawi yayitali, ndikuwonjezera mphamvu yopanga testosterone mthupi lanu lonse.
Momwe mungachepetse DHT
Pali mankhwala ambiri ochepetsa tsitsi la DHT, ndipo ambiri mwa iwo akhala akuwongolera makamaka kupanga kwa DHT ndi kumangiriza kwa receptor. Pali mitundu iwiri ikuluikulu:
- Oletsa. Izi zimalepheretsa DHT kuti ikhale yomanga mpaka ma 5-AR receptors, kuphatikiza ndi omwe ali ndi tsitsi lanu lomwe lingalole kuti DHT ichepetse mafupa
- Zoletsa. Izi zimachepetsa thupi lanu kupanga DHT.
Kumaliza ndalama
Finasteride (Proscar, Propecia) ndi mankhwala am'kamwa, okhawo omwe mumalandira. Zimatchulidwa kuti zili ndi zotsatira zosachepera 87 peresenti mwa mmodzi mwa amuna 3,177, ndi zotsatira zochepa zochepa.
Finasteride imamangiriza ku mapuloteni a 5-AR kuti aletse DHT kuti isamangidwe nawo. Izi zimathandiza kuti DHT isamange zolumikizira pamakutu anu ndikuwasunga kuti asafooke.
Minoxidil
Minoxidil (Rogaine) amadziwika ngati zotumphukira za vasodilator. Izi zikutanthauza kuti imathandizira kukulitsa ndi kumasula mitsempha yamagazi kuti magazi azidutsa mosavuta.
Amagwiritsidwa ntchito ngati mankhwala a magazi. Koma minoxidil amathanso kuthandizira kulimbikitsa kukula kwa tsitsi ikagwiritsidwa ntchito pamutu wanu.
Zamgululi
Biotin, kapena vitamini H, ndi vitamini B wachilengedwe yemwe amathandizira kusintha zakudya ndi zakumwa zomwe mumamwa kuti zikhale mphamvu zomwe thupi lanu lingagwiritse ntchito.
Biotin imathandizanso kukulitsa ndi kusunga keratin, mtundu wa mapuloteni omwe amapezeka tsitsi, misomali, ndi khungu lanu. Kafukufuku sali wotsimikiza kuti chifukwa chiyani biotin ndi yofunika pamatenda a keratin a thupi lanu. Koma kafukufuku wa 2015 akuwonetsa kuti biotin imatha kuthandizanso kuti tsitsi likhalenso komanso kuti tsitsi lomwe lidalipo lisagwe.
Mutha kutenga biotin ngati chowonjezera pakamwa, komanso imapezekanso m'mazira a dzira, mtedza, ndi mbewu zonse.
Makungwa a Pygeum
Pygeum ndi zitsamba zomwe zachotsedwa ku khungwa la mtengo wamatcheri waku Africa. Nthawi zambiri amapezeka ngati chowonjezera chazitsamba chomwe chimatengedwa pakamwa.
Amadziwika bwino ngati mankhwala omwe angakhale othandiza kwa prostate yowonjezera ndi prostatitis chifukwa cha kutseka kwa DHT. Chifukwa cha izi, amaganiziranso kuti ndi njira yothetsera kutayika kwa tsitsi lokhudzana ndi DHT, nayenso. Koma pali kafukufuku wochepa kwambiri wothandizira kugwiritsa ntchito khungwa la pygeum lokha ngati choletsa bwino cha DHT.
Mafuta a dzungu
Mafuta a dzungu ndi china chotchinga DHT chomwe chawonetsedwa kuti chikuyenda bwino.
Mwa amuna 76 omwe ali ndi dazi lachimuna adawonetsa kuwonjezeka kwa 40 peresenti ya kuchuluka kwa tsitsi lakumutu atatenga mamiligalamu 400 a mafuta azitsamba tsiku lililonse kwa milungu 24.
Kafeini
Kafukufuku wocheperako alipo ngati caffeine imatha kulimbikitsa kukula kwa tsitsi. Koma akuwonetsa kuti caffeine itha kuthandiza kupewa tsitsi mwa:
- kupanga tsitsi kumakula
- kukulitsa gawo lokula kwa tsitsi
- kulimbikitsa kupanga keratin
Vitamini B-12 ndi B-6
Kuperewera kwa mavitamini a B, makamaka B-6 kapena B-12, kumatha kuyambitsa zizindikilo zingapo, kuphatikiza kupatulira tsitsi kapena kutayika tsitsi.
Mavitamini a B ndi michere yofunikira pa thanzi lanu lonse, ndipo ngakhale mutenga zowonjezerapo za B-12 kapena B-6 sizingathandize kubwezeretsa tsitsi lomwe latayika, zitha kuthandizira kuti tsitsi lanu likhale lolimba komanso lathanzi powongolera magazi kutuluka m'mutu.
Zotsatira zoyipa za ma DHT blockers
Zotsatira zina zolembedwa za ma DHT blockers ndi awa:
- Kulephera kwa erectile
- kutulutsa umuna msanga kapena kutenga nthawi yayitali kuti ukhale umuna
- Kukula kwakukulu kwamafuta ndi kukoma mtima mozungulira bere
- zidzolo
- kumva kudwala
- kusanza
- Mdima wandiweyani wakhungu lakumaso ndi kumtunda
- congestive mtima kulephera pamchere kapena kusunga madzi, makamaka ndi minoxidil
Zina zomwe zimayambitsa tsitsi
DHT si chifukwa chokha chomwe mungakhale mukuwona tsitsi lanu likuwonda kapena kugwa. Nazi zifukwa zina zingapo zomwe mungathere tsitsi lanu.
Alopecia areata
Alopecia areata ndimomwe mungadzipangire thupi lanu momwe thupi lanu limagwirira zopangira tsitsi kumutu kwanu komanso kwina kulikonse mthupi lanu.
Ngakhale mutha kuwona zingwe zazing'ono zomwe zidatayika poyamba, vutoli limatha kudzetsa dazi lonse pamutu panu, nsidze, nkhope ndi tsitsi.
Ndere zamatsenga
Ndondomeko ya lichen ndi vuto linanso lomwe limapangitsa kuti thupi lanu liwononge khungu lanu, kuphatikizaponso pamutu panu. Izi zitha kubweretsa kuwonongeka kwa follicle komwe kumapangitsa tsitsi lanu kutuluka.
Makhalidwe a chithokomiro
Zomwe zimapangitsa kuti chithokomiro chanu chizipanga kwambiri (hyperthyroidism) kapena chochepa kwambiri (hypothyroidism) cha mahomoni ena amtundu wa chithokomiro omwe amathandizira kuwongolera kagayidwe kanu kamatha kubweretsa tsitsi lakumutu.
Matenda achilendo
Matenda a Celiac ndimomwe amadzipangira okha omwe amachititsa kuti m'mimba musamagwire bwino chifukwa chodya gluten, mapuloteni omwe amapezeka muzakudya monga buledi, oats, ndi mbewu zina. Kutaya tsitsi ndi chizindikiro cha vutoli.
Matenda a khungu
Matenda osiyanasiyana am'mutu, makamaka matenda am'fungasi monga tinea capitis - omwe amatchedwanso kuti ziphuphu zakumutu - amatha kupangitsa khungu lanu kukwiya komanso kukwiya, ndikupangitsa tsitsi kutuluka m'matumba omwe ali ndi kachilombo.
Tsitsi la bamboo
Tsitsi la bamboo limachitika tsitsi lanu likamawoneka lowonda, lopindika, komanso logawika, m'malo mosalala. Ndi chizindikiro chofala cha matenda omwe amadziwika kuti Netherton syndrome, matenda amtundu womwe umabweretsa khungu lochulukirapo komanso kukula kwatsitsi.
Tengera kwina
DHT ndichodziwika bwino, chomwe chimayambitsa kutayika kwa tsitsi lamwamuna komwe kumalumikizidwa ndi chibadwa chanu chakutha kwa tsitsi komanso njira zachilengedwe m'thupi lanu zomwe zimakupangitsani tsitsi lanu mukamakalamba.
Mankhwala ambiri ochepetsa tsitsi omwe amalankhula ndi DHT alipo, ndipo kuchepetsa tsitsi kumatha kukupangitsani kukhala olimba mtima za mawonekedwe anu m'moyo watsiku ndi tsiku. Koma lankhulani ndi dokotala poyamba, chifukwa si mankhwala onse omwe angakhale otetezeka kapena ogwira ntchito kwa inu.