Matenda a mitochondrial: zomwe ali, zoyambitsa, zizindikiro ndi chithandizo

Zamkati

• Zizindikiro zazikulu
• Momwe matendawa amapangidwira
• Zomwe zingayambitse
• Momwe mankhwalawa amachitikira

Matenda a Mitochondrial ndi matenda amtundu komanso obadwa nawo omwe amadziwika ndi kuchepa kapena kuchepa kwa ntchito ya mitochondria, yopanda mphamvu mokwanira mchipindacho, zomwe zitha kubweretsa kufa kwa khungu ndipo, pakapita nthawi, kulephera kwa ziwalo.

Mitochondria ndi timagulu ting'onoting'ono tomwe timakhala m'maselo omwe ali ndi udindo wopanga zoposa 90% yamphamvu yofunikira kuti maselo azigwira ntchito. Kuphatikiza apo, mitochondria imathandizanso pakupanga heme gulu la ma hemoglobins, kagayidwe kake ka cholesterol, ma neurotransmitters komanso kupanga ma radicals aulere. Chifukwa chake, kusintha kulikonse pakugwira ntchito kwa mitochondria kumatha kukhala ndi zovuta m'thupi.

Zizindikiro zazikulu

Zizindikiro za matenda a mitochondrial zimasiyana malinga ndi kusintha kwa thupi, kuchuluka kwa mitochondria komwe kumakhudzidwa mkati mwa khungu komanso kuchuluka kwa maselo omwe akukhudzidwa. Kuphatikiza apo, amatha kusiyanasiyana kutengera komwe ma cell ndi mitochondria amapezeka.

Mwambiri, zizindikilo zomwe zimatha kukhala zowonetsa matenda a mitochondrial ndi izi:

• Minofu kufooka ndi kutayika kwa kulumikizana kwa minofu, popeza minofu imafunikira mphamvu zambiri;
• Kusintha kwazindikiritso ndi kuchepa kwa ubongo;
• Kusintha kwa m'mimba, pakakhala zosintha zokhudzana ndi kugaya kwam'mimba;
• Matenda a mtima, ophthalmic, impso kapena chiwindi.

Matenda a mitochondrial amatha kuwonekera nthawi iliyonse m'moyo, komabe kusintha kwakanthawi kukuwonekera, kuwonjezeka kwambiri kwa zizindikilo ndikukula kwakupha.

Momwe matendawa amapangidwira

Matendawa ndi ovuta, chifukwa zizindikiro za matendawa zitha kuperekanso zina. Matenda a mitochondrial nthawi zambiri amapangidwa pokhapokha ngati zotsatira za mayeso omwe amafunsidwa sizimadziwika.

Kuzindikiritsa matenda a mitochondrial nthawi zambiri kumachitika ndi madotolo omwe amadziwika ndi matenda a mitochondrial kudzera mumayeso amtundu ndi ma molekyulu.

Zomwe zingayambitse

Matenda a Mitochondrial ndi majini, ndiye kuti, amawonekera malinga ndi kupezeka kapena kupezeka kwa kusintha kwa mitochondrial DNA komanso malinga ndi momwe kusinthako kwasinthira. Selo lirilonse m'thupi limakhala ndi mitochondria ma cytoplasm, iliyonse ili ndi chibadwa chake.

Mitochondria yomwe ili mkati mwa selo lomwelo imatha kusiyanasiyana, monganso kuchuluka kwa mtundu wa DNA mu mitochondria kumasiyana pamaselo ndi selo. Matenda a mitochondrial amapezeka mkati mwa selo lomwelo muli mitochondria yomwe majini amasinthidwa ndipo izi zimakhudza magwiridwe antchito a mitochondria. Chifukwa chake, mitochondria yowonongeka kwambiri, mphamvu zochepa zimapangidwa ndikuchulukitsa kufa kwa cell, komwe kumachepetsa kugwira ntchito kwa chiwalo chomwe khungu limakhalamo.

Momwe mankhwalawa amachitikira

Chithandizo cha matenda a mitochondrial cholinga chake ndikulimbikitsa thanzi la munthu ndikuchepetsa kukula kwa matendawa, ndipo kugwiritsa ntchito mavitamini, hydration ndi chakudya chamagulu kungalimbikitsidwe ndi adotolo. Kuphatikiza apo, amalangizidwa motsutsana ndi mchitidwe wolimbitsa thupi kwambiri kuti pasakhale mphamvu yakusowa zofunikira zofunika m'thupi. Chifukwa chake, ndikofunikira kuti munthuyo asunge mphamvu zawo.

Ngakhale kulibe chithandizo chapadera cha matenda a mitochondrial, ndizotheka kuteteza kusintha kosalekeza kwa mitochondrial DNA kuti isapatsidwe kuchokera ku mibadwomibadwo. Izi zitha kuchitika pophatikiza phata la dzira, lomwe limafanana ndi dzira la umuna ndi umuna, ndi mitochondria yathanzi yochokera kwa mayi wina, wotchedwa wopereka wa mitochondria.

Chifukwa chake, mwana wosabadwayo amakhala ndi zinthu za makolo ndi mitochondrial ya munthu wina, yemwe amatchedwa "mwana wa makolo atatu". Ngakhale njogwira ntchito pokhudzana ndi kusokonekera kwa chibadwidwe, njirayi ikuyenera kupitilizidwa ndikuvomerezedwa ndi komiti zamakhalidwe.