Enbrel vs. Humira wa Nyamakazi ya Nyamakazi: Kuyerekezera-Ndi-Mbali

Zamkati

• Chidule
• Zoyambira pa Enbrel ndi Humira
• Mankhwala osokoneza bongo amakhala pafupi
• Kusunga mankhwala
• Mtengo, kupezeka, ndi inshuwaransi
• Zotsatira zoyipa
• Kuyanjana kwa mankhwala
• Gwiritsani ntchito mankhwala ena
• Lankhulani ndi dokotala wanu

Chidule

Ngati muli ndi nyamakazi (RA), nonse mumadziwa bwino mtundu wa zowawa komanso kuuma kolumikizana komwe kumatha kupangitsa ngakhale kudzuka m'mawa kukhala kulimbana.

Enbrel ndi Humira ndi mankhwala awiri omwe angathandize. Onani zomwe mankhwalawa amachita komanso momwe amakumanirana.

Zoyambira pa Enbrel ndi Humira

Enbrel ndi Humira ndi mankhwala omwe amagwiritsidwa ntchito pochizira RA.

Mankhwala onsewa ndi alpha inhibitors a chotupa necrosis factor (TNF). Alpha alpha ndi mapuloteni opangidwa ndi chitetezo chamthupi chanu. Amathandizira kutupa ndi kuwonongeka kwamagulu.

Enbrel ndi Humira amalepheretsa alpha ya TNF yomwe imabweretsa kuwonongeka kwa kutupa kwachilendo.

Malangizo apano samalimbikitsa ma TNF inhibitors ngati mankhwala oyamba a RA. M'malo mwake, amalimbikitsa chithandizo ndi DMARD (monga methotrexate).

Kupatula RA, onse Enbrel ndi Humira amathandizanso:

• matenda a nyamakazi a ana (JIA)
• nyamakazi ya psoriatic (PsA)
• ankylosing spondylitis
• chikwangwani cha psoriasis

Kuphatikiza apo, Humira amathandizanso:

• Matenda a Crohn
• zilonda zam'mimba (UC)
• hidradenitis suppurativa, khungu
• uveitis, kutupa m'diso

Mankhwala osokoneza bongo amakhala pafupi

Enbrel ndi Humira amagwira ntchito chimodzimodzi pochiza RA, ndipo zambiri mwazofanana ndizofanana.

Malangizo sakuwonetsa kukondera kwa TNF inhibitor imodzi pamzake, chifukwa chosowa umboni wotsimikizira kuti imodzi ndiyothandiza kuposa inayo.

Anthu ena amapindula ndikusintha njira ina ya TNF inhibitor ngati yoyamba sigwira ntchito, koma madokotala ambiri amalimbikitsa kuti asinthire mankhwala osiyananso a RA m'malo mwake.

Gome lotsatirali likuwunikira mawonekedwe a mankhwala awiriwa:

Mutha kupeza kuti zolembera zokhazokha za Enbrel SureClick Autoinjector ndi Humira ndizosavuta kugwiritsa ntchito kuposa ma syringes oyikika kale. Amafuna masitepe ochepa.

Anthu nthawi zambiri amawona zabwino zilizonse zamankhwala atatha 2 mpaka 3, koma kuyesa kokwanira kwa mankhwalawa ndi pafupifupi miyezi 3 kuti awone phindu lawo.

Momwe munthu aliyense amayankhira ndi mankhwalawa amasiyana.

Kusunga mankhwala

Enbrel ndi Humira amasungidwa momwemo.

Zonsezi ziyenera kusungidwa mu katoni yoyambirira kuti ziteteze ku kuwonongeka kapena kuwonongeka kwa thupi. Malangizo ena osungira akuwoneka pansipa:

• Sungani mankhwalawa mufiriji pazotentha pakati pa 36 ° F mpaka 46 ° F (2 ° C ndi 8 ° C).
• Mukamayenda, sungani mankhwalawa kutentha kwapakati (68-77 ° F kapena 20-25 ° C) mpaka masiku 14.
  • Tetezani mankhwala ku kuwala ndi chinyezi.
  • Pambuyo masiku 14 kutentha, ponyani mankhwalawo. Osabwezeretsanso mufiriji.
  • Musamaumitse mankhwalawo kapena kugwiritsa ntchito ngati yazizira kenako ndikusungunuka.

Mtengo, kupezeka, ndi inshuwaransi

Enbrel ndi Humira amapezeka pokhapokha ngati mankhwala osokoneza bongo, osati ma generic, ndipo amawononga chimodzimodzi.

Tsamba lawebusayiti ya GoodRx lingakupatseni lingaliro lomveka bwino pamitengo yawo, mitengo yake.

Ambiri omwe amapereka inshuwaransi amafuna chilolezo chisanachitike kuchokera kwa dokotala musanamalize kulipira kapena kumwa mankhwalawa. Funsani kampani yanu ya inshuwaransi kapena pharmacy kuti muwone ngati mukufuna chilolezo cha Enbrel kapena Humira.

Mankhwala anu amatha kukuthandizani kulemba zikalata ngati chilolezo chikufunika.

Ma pharmacies ambiri amakhala ndi Enbrel ndi Humira. Komabe, ndibwino kuyimbira foni yanu pasadakhale kuti muwonetsetse kuti mankhwala anu alipo.

Ma biosimilars amapezeka pamankhwala onsewa. Akayamba kupezeka, ma biosimilars amatha kutsika mtengo kuposa dzina loyambirira la mankhwala.

Biosimilar ya Enbrel ndi Erelzi.

Zojambula ziwiri za Humira, Amjevita ndi Cyltezo, zavomerezedwa ndi US Food and Drug Administration (FDA). Komabe, palibe yomwe ikupezeka kuti igulidwe ku United States.

Amjevita adapezeka ku Europe mu 2018, koma siziyembekezeka kugunda misika yaku US mpaka 2023.

Zotsatira zoyipa

Enbrel ndi Humira ali mgulu lamankhwala omwewo. Zotsatira zake, amakhala ndi zovuta zofananira.

Zina mwa zovuta zoyipa kwambiri ndi izi:

• Zomwe zimachitika pamalo opangira jekeseni
• nkusani matenda
• mutu
• zidzolo

Zotsatira zoyipa zazikulu zingaphatikizepo:

• chiopsezo chowonjezeka cha khansa
• mavuto amanjenje
• mavuto amwazi
• kulephera kwatsopano kapena kukulira kwa mtima
• psoriasis yatsopano kapena yowonjezereka
• thupi lawo siligwirizana
• zochita zokha
• matenda akulu
• kupondereza chitetezo cha mthupi

M'modzi mwa anthu 177 adapeza kuti adalimumab, kapena Humira, ogwiritsa ntchito anali ndi mwayi wopitilira katatu kuti afotokozere za kuwotcha / kulowetsa malo komwe kumawotcha ndikubaya pambuyo pa chithandizo cha miyezi isanu ndi umodzi.

Kuyanjana kwa mankhwala

Nthawi zonse muziuza dokotala wanu za mankhwala, mavitamini, kapena zitsamba zomwe mukumwa. Izi zitha kuthandiza dokotala kuti ateteze kuyanjana kwa mankhwala, komwe kungasinthe momwe mankhwala anu amagwirira ntchito.

Kuyanjana kumatha kukhala kovulaza kapena kolepheretsa mankhwalawo kuti azigwira ntchito bwino.

Enbrel ndi Humira amalumikizana ndi mankhwala omwewo. Kugwiritsa ntchito Enbrel kapena Humira ndi katemera ndi mankhwala otsatirawa kumawonjezera chiopsezo chotenga kachilombo:

• Katemera wamoyo, monga:
  • varicella ndi varicella zoster (nkhuku) katemera
  • Katemera wa herpes zoster (shingles)
  • FluMist, mankhwala opatsirana ndi chimfine
  • katemera wa chikuku, chikuku, ndi rubella (MMR)
  • mankhwala omwe amagwiritsidwa ntchito kupondereza chitetezo chanu chamthupi monga anakinra (Kineret) kapena abatacept (Orencia)
• Mankhwala ena a khansa, monga cyclophosphamide ndi methotrexate
• Mankhwala ena a RA monga sulfasalazine
• Mankhwala ena omwe amasinthidwa ndi puloteni yotchedwa cytochrome p450, kuphatikiza:
  • nkhondo (Coumadin)
  • cyclosporine (Neoral, Sandimmune)
  • chinthaka

Gwiritsani ntchito mankhwala ena

Ngati muli ndi kachilombo ka hepatitis B, kutenga Enbrel kapena Humira kumatha kuyambitsa matenda anu. Izi zikutanthauza kuti mutha kuyamba kukhala ndi matenda a hepatitis B, monga:

• kutopa
• kusowa njala
• chikasu cha khungu lako kapena kuyera kwa maso ako
• kupweteka kumanja kwa mimba yako

Matendawa angayambitsenso chiwindi kulephera komanso kufa. Dokotala wanu adzakuyesani magazi anu kuti awonetsetse kuti mulibe matenda a chiwindi a B musanalandire mankhwalawa.

Lankhulani ndi dokotala wanu

Enbrel ndi Humira ndi mankhwala ofanana kwambiri. Zimathandizanso mofananamo pochepetsa zizindikilo za RA.

Komabe, pali kusiyana pang'ono, komwe kumatha kukupangitsani kukhala kosavuta kugwiritsa ntchito.

Mwachitsanzo, Humira amatha kutengedwa sabata iliyonse kapena sabata iliyonse, pomwe Enbrel imangotengedwa sabata iliyonse.Muthanso kupeza kuti mumakonda ena ogwiritsa ntchito, monga zolembera kapena ma autoinjectors. Makonda amenewo amatha kudziwa mtundu wa mankhwala omwe mungasankhe.

Kudziwa pang'ono za mankhwalawa kungakuthandizeni kuyankhula ndi dokotala kuti mudziwe ngati imodzi mwa mankhwalawa ndi njira yanu.