Ma Docs Akuti Piritsi Latsopano Lovomerezedwa ndi FDA Lochiza Endometriosis Atha Kukhala Osintha Masewera

Zamkati

• Kodi Orilissa amachiza bwanji ululu wa endometriosis?
• Zotsatira zake ndi ziti?
• Mfundo yofunika?
• Onaninso za

Kumayambiriro kwa sabata ino, Food and Drug Administration idavomereza mankhwala atsopano omwe angapangitse kukhala ndi endometriosis kukhala kosavuta kwa amayi opitilira 10 peresenti omwe amakhala ndi zowawa, ndipo nthawi zina zofooketsa.(Yokhudzana: Lena Dunham Anali ndi Hysterectomy Yonse Yothetsera Kupweteka Kwake kwa Endometriosis)

Kutsitsimula mwachangu: "Endometriosis ndi matenda omwe amakhudza azimayi okonda kubereka kumene kulumikizana kwa chiberekero kumakula kunja kwa chiberekero," akutero a Sanjay Agarwal, M.D., pulofesa wa azamba, azachipatala, ndi sayansi yobereka ku UC San Diego Health. "Zizindikirozi zimatha kukhala zosiyanasiyana koma nthawi zambiri zimagwirizanitsidwa ndi nthawi zowawa komanso zowawa pogonana-zizindikirozi zimatha kukhala zoopsa." (Endometriosis ingayambitsenso kusabereka. Kumayambiriro kwa chaka chino, Halsey ananenapo za kuziziritsa mazira ake ali ndi zaka 23 chifukwa cha endometriosis.)

Popeza endometriosis imakhudza amayi 200 miliyoni padziko lonse lapansi, madokotala sakudziwabe modabwitsa zomwe zimayambitsa zilonda zowawa. "Sitikudziwa chifukwa chake azimayi ena amayambitsa matendawa pomwe ena satero kapena chifukwa chake azimayi ena atha kukhala achiwerewere ndipo kwa ena atha kukhala opweteka kwambiri," atero a Zev Williams, MD, Ph.D ., mkulu wa Division of Reproductive Endocrinology and Infertility ku Columbia University Medical Center.

Zomwe madokotala amadziwa ndikuti "estrogen imapangitsa kuti matendawa azizuliranso komanso zizindikilo zake," akutero Dr. Agarwal, ndichifukwa chake endometriosis nthawi zambiri imapweteka kwambiri. Ndizovuta kwambiri, akuwonjezera Dr. Williams. "Zilondazi zimayambitsa kutupa, zomwe zimapangitsa kuti thupi likhale ndi estrogen, zomwe zimayambitsa kutupa, ndi zina zotero," akufotokoza. (Wogwirizana: Julianne Hough Akulankhula Zokhudza Kulimbana Kwake ndi Endometriosis)

"Chimodzi mwazolinga zamankhwala ndikuyesa kuthana ndi vutoli pogwiritsa ntchito mankhwala omwe amachepetsa kutupa kapena kupezeka kwa estrogen," akutero Dr. Williams. "M'mbuyomu, tidachita izi ndi zinthu monga mapiritsi oletsa kubereka omwe amachepetsa mayiyo a estrogen kapena kugwiritsa ntchito mankhwala monga Motrin, omwe ndi anti-inflammatories."

Njira ina yothandizira ndikuletsa thupi kuti lisatulutse estrogen yambiri-njira yomwe idachitidwa kale kudzera mu jakisoni, atero Dr. Williams. Umu ndi momwe Orilissa, mankhwala ovomerezedwa kumene ndi FDA, amagwira ntchito-kupatula pamapiritsi atsiku ndi tsiku.

Madokotala ati mapiritsi, omwe adavomerezedwa ndi FDA koyambirira kwa sabata ino ndipo akuyembekezeka kupezeka koyambirira kwa Ogasiti, atha kukhala osintha masewera kwa amayi omwe ali ndi endometriosis yapakati kapena yowopsa. "Ichi ndichinthu chachikulu mdziko laumoyo wa amayi," akutero Dr. Agarwal. "Kupanga zatsopano pankhani ya endometriosis sikunakhaleko kwazaka zambiri, ndipo njira zamankhwala zomwe timachita zakhala zovuta," akutero. Ngakhale kuti mankhwalawa ndi nkhani zosangalatsa, mtengo wa odwala omwe alibe inshuwalansi siwo. Kupereka mankhwala kwa milungu inayi kudzawononga $ 845 popanda inshuwaransi, akutero a Chicago Tribune.

Kodi Orilissa amachiza bwanji ululu wa endometriosis?

"Kawirikawiri ubongo umapangitsa kuti mazira apange estrogen, yomwe imapangitsa kuti chiberekero cha uterine-ndi endometriosis zilonda zikule," akufotokoza motero Dr. Williams, yemwe anakambirana ndi kampani ya mankhwala kumbuyo kwa Orilissa pamene ikupangidwa. Orilissa mofatsa amapondereza endometriosis-triggering estrogen mwa "kutseka ubongo kuti usatumize chizindikirocho mu ovary kuti apange estrogen," akutero.

Pamene milingo ya estrogen imachepa, momwemonso kupweteka kwa endometriosis. M'mayesero azachipatala oyesedwa ndi FDA a Orilissa, omwe adakhudza pafupifupi azimayi 1,700 omwe ali ndi ululu wocheperako mpaka wowopsa wa endometriosis, mankhwalawa amachepetsa kwambiri mitundu itatu ya ululu wa endometriosis: kupweteka kwa tsiku ndi tsiku, kupweteka kwa nthawi, komanso kupweteka pakugonana.

Zotsatira zake ndi ziti?

Mankhwala apano a endometriosis nthawi zambiri amabwera ndi zotsatirapo monga magazi osakhazikika, ziphuphu, kunenepa, komanso kukhumudwa. "Chifukwa chakuti mankhwala atsopanowa amapondereza estrogen mofatsa, sayenera kukhala ndi zotsatira zofanana zomwe mankhwala ena angakhale nawo," anatero Dr. Agarwal, yemwe anali wofufuza zachipatala pa pulogalamu yophunzira.

Zotsatira zoyipa zambiri ndizochepa - koma chifukwa zimayambitsa kuchepa kwa estrogen, Orilissa amatha kuyambitsa kusamba ngati kuzizira kotentha, ngakhale akatswiri amati palibe umboni kuti ungayambitse kusamba koyambirira.

Choopsa chachikulu ndi chakuti mankhwalawa angayambitse kuchepa kwa mafupa. M'malo mwake, a FDA amalimbikitsa kuti mankhwalawa azingotengedwa kwa zaka ziwiri zokha, ngakhale atakhala ochepa kwambiri. "Chodetsa nkhawa ndi kuchepa kwa mafupa ndikuti kumatha kubweretsa kusweka," akutero Dr. Williams. "Izi ndizofunika kwambiri kwa azimayi ali ndi zaka zosakwana 35 ndipo ali ndi zaka zokulitsa kuchuluka kwa mafupa awo." (Nkhani yabwino: Kuchita masewera olimbitsa thupi kungathandize kuti mafupa anu asachuluke komanso kuchepetsa matenda osteoporosis.)

Ndiye, kodi izi zikutanthauza kuti Orilissa ndi bandi-band wazaka ziwiri basi? Mtundu wa. Mukasiya kumwa mankhwalawa, akatswiriwo akuti ululuwo uyamba kubwerera pang'onopang'ono. Koma ngakhale zaka ziwiri zopanda ululu ndizofunikira. "Cholinga cha kasamalidwe ka mahomoni ndikuyesera kuchedwetsa kukula kwa zotupa za endometriosis kuti muchepetse zizindikirazo komanso mwina kupewa kufunika kochita opaleshoni kapena kuchedwa nthawi yomwe opaleshoniyo ingafunike," akutero Dr. Williams.

Mukamaliza nthawi yanu kumwa mankhwalawa, ma doc ambiri amalimbikitsa kuti mubwererenso kuchipatala monga njira yolerera kuti muthane ndi regrowth, Dr. Williams akuti.

Mfundo yofunika?

Orilissa si chipolopolo chamatsenga, komanso sichiri mankhwala a endometriosis (mwatsoka, kulibe). Koma mapiritsi omwe angovomerezedwa kumene akuimira gawo limodzi lamankhwala, makamaka azimayi omwe akumva kuwawa kwambiri, akutero Dr. Agarwal. "Ino ndi nthawi yosangalatsa kwambiri kwa amayi omwe ali ndi endometriosis."

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