Fexaramine: chomwe chiri ndi momwe chimagwirira ntchito
Zamkati
Fexaramine ndi chinthu chatsopano chomwe chikuwerengedwa chifukwa chimathandiza pakuchepetsa thupi komanso kukulitsa chidwi cha insulin. Kafukufuku wowerengeka wama mbewa onenepa kwambiri amatsimikizira kuti chinthuchi chimapangitsa kuti thupi liwotche mafuta ndipo chifukwa chake limapangitsa kuti muchepetse kunenepa, pochepetsa mafuta, osafunikira kusintha kwa zakudya.
Molekyu iyi ikamizidwa, imatsanzira "chizindikiro" chomwecho chomwe chimatulutsidwa mukamadya. Chifukwa chake, posainira thupi kuti chakudya chatsopano chikudyedwa, njira ya thermogenesis imalimbikitsidwa, "kupanga malo" azakudya zatsopano zomwe zikuyenera kulowetsedwa, koma monga zomwe zikumwa ndi mankhwala opanda zopatsa mphamvu, izi limagwirira kumabweretsa kuwonda.
Mosiyana ndi zinthu zina za agonist za cholandirira chomwecho chomwe chidapangidwa kale, chithandizo cha fexaramine chimachepetsa mphamvu yake m'matumbo, zomwe zimapangitsa kukula kwa ma peptide am'matumbo, zomwe zimapangitsa m'matumbo athanzi komanso kuchepa kwa kutupa kwadongosolo.
Zonsezi zimapangitsa fexaramine kukhala woyenera kuchiza kunenepa kwambiri komanso matenda omwe amakhudzana ndi kunenepa kwambiri, kuphatikiza mtundu wa 2 shuga ndi matenda a chiwindi chamafuta.
Kuphatikiza apo, zapezekanso kuti fexaramine imatsanzira zina mwazinthu zopindulitsa zomwe zimachitika chifukwa cha opaleshoni ya bariatric, yomwe ndi njira yabwino kwambiri yochepetsera thupi, kukonza thanzi la anthu onenepa kwambiri. Pazochitika zonsezi, kuchepa kwa insulin kumayendetsedwa bwino, kuchuluka kwa shuga kumatsika, mawonekedwe a bile acid amakula, kutupa m'mimba kumachepa ndipo, pamapeto pake, thupi limachepa.
Kafukufuku wamtsogolo athandizira kuwulula ngati fexaramine itha kubweretsa chithandizo chatsopano cha kunenepa kwambiri.
Kodi mankhwalawa amakhala ndi zovuta zina?
Fexaramine akuphunziridwabe ndipo, chifukwa chake, sizotheka kudziwa ngati zimayambitsa zovuta. Komabe, mosiyana ndi mankhwala ena omwe amagwiritsidwa ntchito kuonda, fexaramine imagwira ntchito yake osalowetsedwa m'magazi, kupewa zovuta zina zomwe zimachitika chifukwa cha mankhwala ambiri ochepetsa thupi.
Kodi idzagulitsidwa liti?
Sizikudziwika ngati mankhwalawa angalowe mumsika komanso kuti adzagulitsidwe liti, popeza akadali munthawi yophunzira, koma akuganiza kuti ngati atakhala ndi zotsatira zabwino, atha kuyambitsa pafupifupi 1 mpaka 6 zaka.