Acromegaly ndi gigantism: zizindikiro, zoyambitsa ndi chithandizo

Zamkati

• Zizindikiro zazikulu
• Kodi zovuta ndizotani
• Momwe mungatsimikizire matendawa
• Momwe mankhwalawa amachitikira

Gigantism ndi matenda osowa omwe thupi limatulutsa mahomoni ochulukirapo, omwe nthawi zambiri amayamba chifukwa cha chotupa chosaopsa m'matumbo a pituitary, chotchedwa pituitary adenoma, chomwe chimapangitsa ziwalo ndi ziwalo za thupi kukula kuposa zachilendo.

Matendawa akangobadwa, amadziwika kuti gigantism, komabe, ngati matendawa amabwera atakula, nthawi zambiri azaka pafupifupi 30 kapena 50, amadziwika kuti acromegaly.

Pazochitika zonsezi, matendawa amayamba chifukwa cha kusintha kwa minyewa ya pituitary, komwe ubongo umatulutsa mahomoni okula, motero chithandizo chimachitidwa kuti muchepetse kupanga kwa mahomoni, komwe kumatha kuchitidwa kudzera pakuchita opareshoni., Kugwiritsa ntchito mankhwala kapena radiation, Mwachitsanzo.

Zizindikiro zazikulu

Akuluakulu omwe ali ndi acromegaly kapena ana omwe ali ndi gigantism nthawi zambiri amakhala ndi mikono, miyendo ndi milomo yayikulu, komanso nkhope zowuma. Kuphatikiza apo, mahomoni okula owonjezera amathanso kuyambitsa:

• Kuyaka kapena kutentha m'manja ndi m'mapazi;
• Shuga wambiri m'magazi;
• Kuthamanga;
• Ululu ndi kutupa m'malo olumikizirana mafupa;
• Masomphenya awiri;
• Zowonjezera mandible;
• Sinthani potuluka;
• Kukula kwa chilankhulo;
• Kutha msinkhu mochedwa;
• Kusamba kosasamba;
• Kutopa kwambiri.

Kuphatikiza apo, popeza pali kuthekera kwakuti mahomoni owonjezera opangidwa ndi chotupa chosaopsa m'matumbo a pituitary, zizindikilo zina monga mutu wokhazikika, mavuto amaso kapena kuchepa chilakolako chogonana, mwachitsanzo, zitha kuonekanso.

Kodi zovuta ndizotani

Zina mwazovuta zomwe kusinthaku kumatha kubweretsa kwa wodwala ndi izi:

• Matenda ashuga;
• Kugonana;
• Kutaya masomphenya;
• Kukula kwa mtima;

Chifukwa cha zovuta izi, ndikofunikira kupita kwa dokotala ngati mukuganiza kuti matendawa kapena kusintha kwakukula.

Momwe mungatsimikizire matendawa

Pomwe pali kukayikira kuti muli ndi gigantism, kuyezetsa magazi kuyenera kuchitidwa kuti muwone kuchuluka kwa IGF-1, puloteni yomwe imakulitsidwa pamene kuchuluka kwa mahomoni amakuliranso kuposa momwe zimakhalira, kuwonetsa acromegaly kapena gigantism.

Pambuyo pa mayeso, makamaka kwa wamkulu, CT scan itha kulamulidwanso, mwachitsanzo, kuti izindikire ngati pali chotupa mumatumbo a pituitary chomwe chingasinthe magwiridwe ake. Nthawi zina, adokotala amatha kuyitanitsa kuchuluka kwa kukula kwa mahomoni.

Momwe mankhwalawa amachitikira

Chithandizo cha gigantism chimasiyanasiyana kutengera zomwe zimayambitsa mahomoni okula kwambiri. Chifukwa chake, ngati pamakhala chotupa m'matumbo, nthawi zambiri amalimbikitsidwa kuchitidwa opaleshoni kuti achotse chotupacho ndikubwezeretsanso kutulutsa kolondola kwa mahomoni.

Komabe, ngati palibe chifukwa choti ntchito ya pituitary isinthe kapena ngati opaleshoniyi sagwira ntchito, adotolo angangowonetsa kugwiritsa ntchito ma radiation kapena mankhwala, monga ma somatostatin analogs kapena dopamine agonists, mwachitsanzo, omwe ayenera kugwiritsidwa ntchito kwa moyo wonse kuti mahomoni azilamuliridwa.