Mlembi: Randy Alexander
Tsiku La Chilengedwe: 24 Epulo 2021
Sinthani Tsiku: 19 Novembala 2024
Anonim
Pharmacology - Glucocorticoids
Kanema: Pharmacology - Glucocorticoids

Zamkati

Chidule

Matenda ambiri amakhudzana ndi kutupa. Glucocorticoids ndi othandiza poletsa kutupa kovulaza komwe kumachitika chifukwa chamatenda ambiri amthupi. Mankhwalawa alinso ndi ntchito zina zambiri. Komabe, amabweranso ndi zovuta. Izi zitha kukhala zovuta, makamaka ngati mugwiritsa ntchito mankhwalawa motalika kwambiri.

Kodi glucocorticoids ndi chiyani?

Mankhwala a glucocorticoid ndi mitundu yopangidwa ndi anthu ya glucocorticoids, ma steroids omwe amapezeka mwachilengedwe mthupi lanu. Ali ndi ntchito zambiri. Imodzi ndiyo kusokoneza kutupa mwa kusunthira m'maselo ndikutsitsa mapuloteni omwe amalimbikitsa kutupa. Amathandizanso thupi lanu kuthana ndi kupsinjika ndikuwongolera momwe thupi lanu limagwiritsira ntchito mafuta ndi shuga.

Chifukwa ma glucocorticoids ali ndi ntchito zambiri, zopangidwa ndi anthu kapena ma glucocorticoids apangidwa kuti athandizire kuthana ndi zovuta zosiyanasiyana.

Mndandanda wa mankhwala a glucocorticoid

Zitsanzo za mankhwala a glucocorticoid ndi awa:

  • beclomethasone
  • betamethasone
  • mphukira
  • cortisone
  • dexamethasone
  • hydrocortisone
  • methylprednisolone
  • chibadul
  • mbalambanda
  • wochita

Zomwe glucocorticoids zimachiza

Kupanga glucocorticoids kumatha kukhala kwamphamvu kwambiri kuposa ma steroids omwe amabwera mwachilengedwe. Amagwiritsidwa ntchito pochiza matenda ambiri.


Matenda osokoneza bongo

Matenda omwe amadzichotsera okha amatha kuwononga kwambiri kutupira thupi likadziwukira molakwika. Matenda omwe amadzichotsera okha ndi awa:

  • matenda ofoola ziwalo
  • nyamakazi
  • matenda opatsirana
  • anam`peza matenda am`matumbo
  • psoriasis
  • chikanga

Glucocorticoids imatha kuchepetsa momwe maselo amthupi amathandizira. Izi zimathandiza kuchepetsa kuwonongeka kwamkati kuchokera ku matendawa. Amaletsa kutupa chifukwa chazomwe zimachitika. Izi zitha kuchepetsa kupweteka, kutupa, kuphwanya, ndi kuyabwa.

Matenda ndi mphumu

Matenda ndi chifuwa cha mphumu ndi momwe thupi lanu limayankhira pazinthu zopanda vuto lililonse. M'mikhalidwe imeneyi, zinthu monga mungu kapena mtedza zimatha kuyambitsa kukwiya kotupa. Zizindikiro zimatha kusiyanasiyana ndikuphatikiza:

  • kuyabwa
  • kuyabwa, maso amadzi
  • mutu wopepuka
  • kufiira, ming'oma, kapena zidzolo
  • Kuseza ndi kutsekeka kapena mphuno yothamanga
  • kutupa kwa nkhope yanu, milomo, kapena mmero
  • kuvuta kupuma

Glucocorticoids amatha kuthana ndi izi mopitilira muyeso poletsa kutupa ndikukhazikitsa chitetezo cha mthupi.


Kulephera kwa adrenal

Ngati muli ndi kulephera kwa adrenal, thupi lanu silimatha kupanga cortisol yokwanira. Izi zitha kukhala zotsatira za matenda monga Addison's disease kapena kuchotsedwa kwa ma gland anu a adrenal. Glucocorticoids itha kugwiritsidwa ntchito m'malo mwa cortisol yomwe thupi lanu silingathe kupanganso.

Mtima kulephera

Kugwiritsa ntchito kwakanthawi kochepa (masiku ochepera 7) a glucocorticoids kungathandize kuthana ndi vuto la mtima powonjezera kuthekera kwa thupi lanu kuyankha kwa okodzetsa ena. Komabe, iyi si ntchito wamba.

Khansa

Glucocorticoids itha kugwiritsidwa ntchito pochiza khansa kuti muchepetse zovuta zina za chemotherapy. Angagwiritsidwenso ntchito kupha maselo ena a khansa m'matenda ena a khansa, kuphatikiza:

  • pachimake lymphoblastic khansa
  • Matenda a m'magazi a lymphoblastic
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
  • angapo myeloma

Mavuto akhungu

Matenda a khungu kuyambira pa eczema mpaka poizoni ivy amathandizidwa ndi glucocorticoids. Izi zimaphatikizapo mafuta owerengera komanso owerengera omwe mumagwiritsa ntchito pakhungu lanu ndi mankhwala omwe mumamwa.


Opaleshoni

Glucocorticoids itha kugwiritsidwa ntchito munthawi yovuta ya ma neurosurgeries. Amachepetsa kutupa m'matumba osakhwima. Amaperekedwanso pambuyo pokhazikitsa chiwalo chothandizira kuteteza chitetezo cha mthupi kukana chiwalo choperekacho.

Zotsatira zoyipa

Glucocorticoids imatha kumveka ngati mankhwala ozizwitsa, koma imakhala ndi zovuta zina. Zina mwa zotsatirazi zitha kukhala zowononga kwambiri. Ichi ndichifukwa chake mankhwalawa sanapatsidwe kuti agwiritsidwe ntchito kwakanthawi.

Mankhwalawa akhoza:

  • onjezerani shuga m'magazi anu, omwe amatha kuyambitsa matenda ashuga kwakanthawi kwakanthawi
  • kupondereza kuthekera kwa thupi lanu kuyamwa calcium, zomwe zingayambitse kufooka kwa mafupa
  • onjezani cholesterol yanu ndi milingo ya triglyceride
  • kuonjezera ngozi ya zilonda ndi gastritis
  • kuchedwetsa kuchira kwa bala, komwe kumafunikira kuchuluka kwakatupa
  • kupondereza chitetezo cha m'thupi lanu ndikupangitsani kuti muzitha kutenga matenda

Kugwiritsa ntchito glucocorticoids kwa nthawi yayitali kumatha kuyambitsa kuwonongeka kwa minofu. Zitha kupanganso matenda a Cushing's, omwe angayambitse:

  • kunenepa kwambiri pakati pamapewa anu
  • nkhope yozungulira
  • kunenepa
  • pinki otambasula
  • mafupa ofooka
  • matenda ashuga
  • kuthamanga kwa magazi
  • khungu lowonda
  • kuchira pang'onopang'ono
  • ziphuphu
  • kusamba kosasamba nthawi zonse
  • kuchepa kwa libido
  • kutopa
  • kukhumudwa

Ngati mwagwiritsa ntchito glucocorticoids kwa milungu yoposa ingapo, dokotala wanu atha kukupatsani mlingo pang'onopang'ono m'malo mosiya kumwa zonse mwakamodzi. Izi zimathandiza kupewa zotsatira zakusiya. Thupi lanu mwachilengedwe limapanga ma glucocorticoids, koma mukayamba kuwamwa ngati mankhwala, thupi lanu limadzichepetsera lokha. Mukasiya kumwa ma glucocorticoids, thupi lanu limafunikira nthawi kuti liyambenso kudzipangira lokha pamiyeso yabwinobwino.

Lankhulani ndi dokotala wanu

Glucocorticoids atha kukhala mankhwala othandiza pamankhwala osiyanasiyana. Komabe, ndikofunikira kuti muchepetse kufunikira kwa mankhwala a glucocorticoid motsutsana ndi zotsatirapo zake. Ngati dokotala wanu akupatsani mankhwala a glucocorticoid, auzeni za zovuta zilizonse zomwe muli nazo. Ndikofunikanso kumwa mankhwalawa monga momwe adalangizira, kuphatikiza mukamawaletsa. Dokotala wanu akhoza kukulepheretsani kumwa mankhwala anu pang'onopang'ono kuti mupewe kuchoka.

Yotchuka Pa Portal

Momwe mungasankhire mkaka wabwino kwambiri kwa wakhanda

Momwe mungasankhire mkaka wabwino kwambiri kwa wakhanda

Chi ankho choyamba chodyet a mwana m'miyezi yoyamba ya moyo chiyenera kukhala mkaka wa m'mawere, koma izotheka nthawi zon e, ndipo kungakhale kofunikira kugwirit a ntchito mkaka wa khanda ngat...
Warfarin (Coumadin)

Warfarin (Coumadin)

Warfarin ndi mankhwala a anticoagulant omwe amagwirit idwa ntchito pochiza matenda amtima, omwe amalet a kuundana komwe kumadalira vitamini K. izimakhudza kuundana komwe kwapangidwa kale, koma kumatha...