Kodi grangenomatosis ya Wegen ndi chiyani komanso momwe mungamuthandizire

Zamkati

• Zizindikiro zazikulu
• Momwe muyenera kuchitira
• Momwe matendawa amapangidwira
• Zomwe zimayambitsa Wegener granulomatosis

Grangenomatosis ya Wegener, yomwe imadziwikanso kuti granulomatosis ndi polyangiitis, ndi matenda osowa kwambiri omwe amapangitsa kutupa m'mitsempha yamagazi m'malo osiyanasiyana amthupi, kuchititsa zizindikilo monga kupindika kwa mpweya, kupuma movutikira, zotupa pakhungu, magazi a m'mphuno, kutupa m'makutu, malungo , malaise, kusowa chilakolako kapena kukwiya m'maso.

Popeza ndimatenda omwe amabwera chifukwa chodzitchinjiriza thupi, chithandizo chake chimachitika makamaka ndi mankhwala oyang'anira dongosolo la inume, monga corticosteroids ndi ma immunosuppressants, ndipo ngakhale kulibe mankhwala, matendawa amayang'aniridwa bwino, kulola kuti moyo ukhale wabwinobwino.

Grangenomatosis ya Wegen ndi gawo limodzi la matenda omwe amatchedwa vasculitis, omwe amadziwika pakupangitsa kutupa ndi kuwonongeka kwa mitsempha yamagazi, yomwe imatha kusokoneza kugwira ntchito kwa ziwalo zosiyanasiyana. Mvetsetsani bwino mitundu ya vasculitis yomwe ilipo komanso momwe mungaizindikire.

Zizindikiro zazikulu

Zina mwazizindikiro zazikulu zoyambitsidwa ndi matendawa ndi monga:

• Sinusitis ndi magazi a m'mphuno;
• Chifuwa, kupweteka pachifuwa ndi kupuma movutikira;
• Mapangidwe zilonda mu mucosa mphuno, zomwe zingachititse kuti kudziwika chilema ndi chishalo mphuno;
• Kutupa m'makutu;
• Conjunctivitis ndi kutupa kwina m'maso;
• Kutentha thupi ndi thukuta usiku;
• Kutopa ndi kutopa;
• Kutaya njala ndi kuonda;
• Olowa kupweteka ndi kutupa m'malo olumikizirana mafupa;
• Kupezeka kwa magazi mkodzo.

Nthawi zambiri, pakhoza kukhala kuwonongeka kwa mtima, komwe kumabweretsa matenda a pericarditis kapena zotupa m'mitsempha yamitsempha, kapena yamanjenje, yomwe imabweretsa zizindikiritso zamitsempha.

Kuphatikiza apo, odwala omwe ali ndi matendawa ali ndi chizolowezi chowonjezeka chokhala ndi thrombosis, ndipo chisamaliro chiyenera kulipidwa pazizindikiro zomwe zikuwonetsa vutoli, monga kutupa ndi kufiyira m'miyendo.

Momwe muyenera kuchitira

Chithandizo cha matendawa chimaphatikizapo kugwiritsa ntchito mankhwala omwe amathandiza kuteteza chitetezo cha mthupi, monga Methylprednisolone, Prednisolone, Cyclophosphamide, Methotrexate, Rituximab kapena njira zochiritsira zachilengedwe.

Maantibayotiki a sulfamethoxazole-trimethoprim amatha kuphatikizidwa ndi chithandizo ngati njira yochepetsera kubwereranso kwa matenda amtundu wina.

Momwe matendawa amapangidwira

Pofuna kudziwa kuti Wegener's granulomatosis ndi chiyani, adotolo awunika zomwe zapezeka ndikuwunika thupi, komwe kumatha kupereka zizindikilo zoyambirira.

Kenako, kuti atsimikizire kuti ali ndi matendawa, kuyerekezera kwakukulu ndikupanga chidutswa cha ziwalo zomwe zakhudzidwa, zomwe zikuwonetsa kusintha komwe kumagwirizana ndi vasculitis kapena necrotizing kutupa kwa granulomatous. Mayesero amathanso kulamulidwa, monga muyeso wa antibody wa ANCA.

Kuphatikiza apo, ndikofunikira kuti adotolo asiyanitse matendawa ndi ena omwe atha kukhala ndi ziwonetsero zofananira, monga khansa yamapapo, lymphoma, kugwiritsa ntchito cocaine kapena lymphomatoid granulomatosis, mwachitsanzo.

Zomwe zimayambitsa Wegener granulomatosis

Zomwe zimayambitsa zomwe zimayambitsa matendawa sizikudziwika, komabe, zimadziwika kuti ndizokhudzana ndi kusintha kwa chitetezo cha mthupi, chomwe chingakhale zigawo za thupi lenilenilo kapena zinthu zakunja zomwe zimalowa mthupi.