Kuthamanga kapena kutsika kwa hemoglobin: tanthauzo lake ndi malingaliro ake

Zamkati

• Mpweya wa hemoglobin
• Hemoglobin mumkodzo

Hemoglobin, kapena Hb, ndi gawo limodzi lama cell ofiira ofiira ndipo ntchito yake yayikulu ndikutumiza oxygen kuziphuphu. Hb imakhala ndi gulu la heme, lomwe limapangidwa ndi chitsulo, ndi maunyolo a globin, omwe amatha kukhala alpha, beta, gamma kapena delta, zomwe zimabweretsa mitundu yayikulu ya hemoglobin, monga:

• HbA1, yomwe imapangidwa ndi maunyolo awiri a alpha ndi maunyolo awiri a beta ndipo imapezeka m'magazi ambiri;
• HbA2, yomwe imapangidwa ndi maunyolo awiri a alpha ndi maunyolo awiri a delta;
• HbF, yomwe imapangidwa ndi maunyolo awiri a alpha ndi maunyolo awiri a gamma ndipo imapezeka kwambiri mwa ana obadwa kumene, ndipo chidwi chawo chimachepa malinga ndikukula.

Kuphatikiza pa mitundu yayikuluyi, pali Hb Gower I, Gower II ndi Portland, omwe amapezeka pamasiku owumbidwa, ndi kuchepa kwa ndende zawo ndikuwonjezeka kwa HbF pamene kubadwa kukuyandikira.

Mpweya wa hemoglobin

Glycated hemoglobin, yotchedwanso glycosylated hemoglobin, ndiyeso yoyezetsa matenda yomwe cholinga chake ndi kuyesa kuchuluka kwa shuga wazachipatala m'magazi m'miyezi itatu, kukhala koyenera kwambiri kuwunika ndikuwunika matenda ashuga, komanso kuwunika kuopsa kwake.

Mtengo wabwinobwino wa hemoglobin wa glycated ndi 5.7% ndipo matenda ashuga amatsimikiziridwa ngati mtengo wake uli wofanana kapena woposa 6.5%. Dziwani zambiri za hemoglobin ya glycated.

Hemoglobin mumkodzo

Kupezeka kwa hemoglobin mumkodzo kumatchedwa hemoglobinuria ndipo nthawi zambiri kumawonetsa matenda a impso, malungo kapena poyizoni wazitsulo. Kuzindikiritsa hemoglobin mumkodzo kumachitika kudzera mumayeso osavuta a mkodzo, otchedwa EAS.

Kuphatikiza pa hemoglobin, hematocrit values ​​limasonyezanso kusintha kwa magazi monga kuchepa magazi ndi khansa ya m'magazi. Onani kuti hematocrit ndi chiyani ndikumvetsetsa zotsatira zake.