Kodi Oxycodone Imakhala Motalika Motani M'dongosolo Lanu?

Zamkati

• Zimatenga nthawi yayitali bwanji kumva zotsatira za oxycodone?
• Zimatenga nthawi yayitali bwanji kuti oxycodone iwonongeke?
• Zinthu zomwe zimakhudza kutalika kwa zotsatira za oxycodone
• Zaka
• Jenda
• Ntchito ya chiwindi
• Ntchito ya impso
• Mwatenga nthawi yayitali bwanji mukutenga oxycodone
• Mowa
• Mankhwala ena
• Zizindikiro zosiya
• Tengera kwina

Chidule

Oxycodone ndi mankhwala opioid omwe amagwiritsidwa ntchito kuti athetse ululu wopweteka kwambiri kwa akulu omwe sangathe kulandira mankhwala ena opweteka. Oxycodone itha kuperekedwa pambuyo povulala, zoopsa, kapena opaleshoni yayikulu. Zitha kuperekedwanso kuti zithetse mitundu ina ya zowawa, monga khansa.

Maina amtundu wa oxycodone wotulutsidwa mwachangu ndi awa:

• Oxaydo
• Zamgululi
• Wolemba Roxybond
• Oxy IR

Maina a mayina amtundu wa oxycodone omwe amawongoleredwa kapena kutulutsidwa ndi awa:

• OxyContin CR (kumasulidwa)
• Xtampza ER (yomasulidwa)

Palinso mankhwala osakaniza omwe amaphatikizapo oxycodone, monga:

• oxycodone pamodzi ndi acetaminophen (Percocet)
• oxycodone pamodzi ndi acetaminophen (Xartemis XR)
• oxycodone pamodzi ndi aspirin (generic ikupezeka)
• oxycodone kuphatikiza ibuprofen (generic ikupezeka)

Oxycodone imachokera ku chomera cha poppy. Amamangirira mu opioid receptor ndikuletsa kumva kupweteka. Popeza oxycodone imagwira ntchito m'malo osangalatsa aubongo, imatha kuchitira nkhanza komanso kusuta. Pachifukwa ichi, oxycodone imagawidwa ngati chinthu cholamulidwa ndi feduro (C-II).

Ngati mwapatsidwa mankhwala a oxycodone, mutha kukhala ndi chidwi chofuna kudziwa kuti zotsatira zake zikhala zazitali bwanji mthupi lanu, komanso momwe mankhwalawa angawonekere poyesa mankhwala. Ndikofunikanso kumvetsetsa zomwe muyenera kuchita ngati mungaganize zosiya kumwa oxycodone. Kuyimitsa mwadzidzidzi mankhwalawo kumatha kudzetsa zizindikiritso zakusiya.

Zimatenga nthawi yayitali bwanji kumva zotsatira za oxycodone?

Kuchuluka kwa oxycodone yofunikira ku analgesia (kupweteka) kumasiyana mosiyanasiyana pakati pa anthu. Kawirikawiri, dokotala amayamba pa mlingo wochepa ndikuwonjezera mlingo pang'onopang'ono mpaka kupweteka kwanu kutayendetsedwa bwino. Anthu omwe adamwa mankhwala a opioid m'mbuyomu angafunikire kumwa mlingo waukulu kuti athe kumva kupweteka.

Oxycodone imatengedwa pakamwa (pakamwa) ndipo imayenera kutengedwa ndi chakudya. Muyenera kuyamba kumva zotsatira za oxycodone mumphindi 20 mpaka 30 zokha. Oxycodone imafika pachimake m'magazi pafupifupi ola limodzi kapena awiri kutsatira kumeza. Mafotokozedwe owonjezeredwa komanso owongoleredwa amatha kutenga maola atatu kapena anayi kuti afike pachimake m'magazi.

Popita nthawi, mutha kupanga kulolerana kwa oxycodone. Izi zikutanthauza kuti zingatenge nthawi yayitali kuti mumve kupweteka kapena mpumulo ungakhale wopanda mphamvu. Izi zikachitika, dokotala wanu angafune kuwonjezera mlingo wanu kapena akusinthireni ku mtundu wina wa mankhwala opweteka. Musatenge mlingo waukulu wa oxycodone osalankhula ndi dokotala poyamba.

Zimatenga nthawi yayitali bwanji kuti oxycodone iwonongeke?

Njira imodzi yodziwira kutalika kwa mankhwala m'thupi lanu ndiyo kuyeza theka la moyo wake. Hafu ya moyo ndi nthawi yomwe zimatengera kuti theka la mankhwalawo achotsedwe mthupi.

Mafomu otulutsidwa nthawi yomweyo a oxycodone amakhala ndi theka la moyo wa maola 3.2. Mwanjira ina, zimatenga maola 3.2 kuti munthu wamba athetse theka la mlingo wa oxycodone. Mitundu yoyendetsedwa / yotulutsidwa ya oxycodone imakhala ndi theka la moyo wa maola 4.5 mpaka maola 5.6, pafupifupi.

Zimatengera theka la miyoyo kuti athetse mankhwala. Popeza aliyense amasakaniza mankhwala mosiyanasiyana, theka la moyo limasiyanasiyana malinga ndi munthu. Kwa anthu ambiri, oxycodone imatsuka magazi mkati mwa maola 24, komabe imatha kupezeka m'malovu, mkodzo, kapena tsitsi kwa nthawi yayitali kuposa pamenepo.

Oxycodone imapezeka mu:

• malovu kwa tsiku limodzi kapena anayi mutamwa mlingo womaliza
• mkodzo kwa masiku atatu kapena anayi mutalandira mlingo womaliza
• Tsitsi kwa masiku 90 pambuyo poti mlingo womaliza watengedwa

Mutha kusiya "kumva" kupweteka kwa oxycodone nthawi yayitali isanakwane. Ichi ndichifukwa chake dokotala wanu atha kutenga piritsi limodzi la oxycodone maola anayi kapena asanu aliwonse mukakhala kuti mukumva kuwawa.

Makina owongoleredwa kapena otulutsidwa amatenga nthawi yayitali, chifukwa chake amatengedwa maola 12 aliwonse.

Zinthu zomwe zimakhudza kutalika kwa zotsatira za oxycodone

Zinthu zingapo zimakhudza nthawi yomwe oxycodone amatulutsa kuti ayeretse thupi. Izi zikuphatikiza:

Zaka

Magazi a oxycodone awonetsedwa kuti ndi 15% okwera mwa okalamba (opitilira zaka 65) poyerekeza ndi achikulire. Zitha kutenga nthawi yayitali kuti okalamba achotse oxycodone m'dongosolo lawo.

Jenda

Malinga ndi phukusi la OxyContin, kuchuluka kwa oxycodone kwa maphunziro azimayi athanzi kunali 25% kuposa amuna. Zomwezi zidawonekanso m'maphunziro a Xtampza ER. Chifukwa cha izi sichikudziwika.

Ntchito ya chiwindi

Hafu ya moyo wa oxycodone imawonjezeka ndi maola 2.3 mwa anthu omwe ali ndi vuto la chiwindi. Izi zikutanthauza kuti zimatenga nthawi yayitali kuchotsa oxycodone mthupi.

Ntchito ya impso

Kafukufuku wina anapeza kuti theka la moyo wa oxycodone limakula ndi ola limodzi mwa anthu omwe ali ndi vuto la impso.

Mwatenga nthawi yayitali bwanji mukutenga oxycodone

Mukatenga oxycodone pafupipafupi, imatha kudziunjikira m'matupi amafuta mthupi lanu. Izi zikutanthauza kuti nthawi yayitali yomwe mwakhala mukutenga oxycodone, zimatenga nthawi yayitali kuti muchotsedwe mthupi.

Mowa

Zotsatira za oxycodone zimawonjezeka mukamamwa mowa. Sikuti kungotenga nthawi yayitali kuchotsa oxycodone mthupi lanu, komanso kumatha kubweretsa zovuta zoyipa, kuphatikizaponso kuchuluka kwakupha.

Mankhwala ena

Oxycodone imakonzedwa ndi thupi lanu kudzera munjira yotchedwa cytochrome P450 3A (CYP3A). Mankhwala omwe amaletsa CYP3A4 zimapangitsa kuti thupi lanu likhale ndi vuto losokoneza oxycodone. Kutenga oxycodone ndi mankhwala otsatirawa kumatha kubweretsa mavuto akulu, kuphatikizapo kupuma kwamatenda:

• mankhwala a macrolide, monga erythromycin
• azole antifungal agents, monga ketoconazole
• protease inhibitors

Kapenanso, mankhwala omwe amachititsa CYP3A, monga rifampin, amachepetsa zotsatira za oxycodone.

Zizindikiro zosiya

Osasiya kumwa mwadzidzidzi oxycodone osakambirana ndi dokotala chifukwa mutha kukhala ndi zizindikilo zoopsa zosiya. Zizindikiro zobwerera m'mbuyo zimachitika thupi likamadalira mankhwala.

Ngati mukumva zizindikiro zakutha, sizitanthauza kuti ndinu osokoneza bongo wa oxycodone. Kudalira ndikosiyana ndi kuledzera. Pakudalira mankhwala, thupi lakhala likuzolowera kupezeka kwa mankhwala, ndiye mukaleka kumwa mankhwalawo modzidzimutsa, mudzakumana ndi zizindikilo zodziwikiratu zomwe zimadziwika kuti zizindikiritso zakutha.

Izi zingaphatikizepo:

• kusakhazikika
• maso amadzi
• mphuno
• kuyasamula
• kulephera kugona
• kukokana kwa minofu
• zophatikizana
• kusanza
• thukuta
• kupuma mofulumira
• kugunda kwamtima mwachangu

Kudalira nthawi zambiri kumachitika mpaka patatha milungu ingapo mutamwa mankhwalawa mosasinthasintha. Dokotala wanu amatha kuchepetsa mlingo wanu pang'onopang'ono pakapita nthawi kuti mupewe kuchoka. Izi zimatchedwa tapering. Ndikulimbikitsidwa kuti mlingowu muchepetsedwe pang'onopang'ono kwinaku mukuwunika mosamala zisonyezo zakusiya.

Ngati mukukumana ndi zizindikiritso zakutha, amatha kuwerengedwa kuti ndi ofatsa, ochepa, kapena okhwima. Aliyense amakumana ndi kusiya mosiyanasiyana, koma zizindikilo zake zimayamba kusintha mkati mwa maola 72 ndikuchepetsa kwambiri mkati mwa sabata. Dokotala wanu akhoza kukuthandizani kuthana ndi matenda anu.

Tengera kwina

Kupweteka komwe kumatulutsa oxycodone kumatha pakatha maola anayi kapena asanu ndi limodzi, koma mankhwalawa amatha kupezeka m'malovu ndi mkodzo kwa masiku anayi kapena m'matsitsi masiku 90 pambuyo pa mlingo womaliza.

Palinso zinthu zingapo zomwe zingasinthe nthawi yomwe oxycodone amayeretsera thupi, kuphatikiza:

• zaka
• jenda
• chiwindi ndi impso
• mwatenga nthawi yayitali bwanji mukutenga oxycodone
• mankhwala ena

Simuyenera kumwa mowa kapena kumwa mankhwala ena am'njira mukamamwa oxycodone chifukwa izi zimawonjezera chiopsezo chokumana ndi zovuta zoyipa, kuphatikizapo kupuma kwambiri. Uzani dokotala wanu ngati mukumwa mankhwala ena aliwonse.

Musamamwe zochuluka kuposa kuchuluka kwanu kwa oxycodone, ngakhale mukuwona kuti mankhwalawo sakugwira ntchito. Ndizotheka kugwiritsira ntchito oxycodone.

Funani chisamaliro chadzidzidzi ngati mungakhale ndi izi mukalandira oxycodone:

• kuvuta kupuma
• adachepetsa kapena kusiya kupuma
• ozizira, khungu lowundana
• kutaya chidziwitso kapena kukomoka
• kugona kwambiri
• ophunzira ochepa
• Minofu yofooka kapena yofooka
• kusanza

Opioids monga oxycodone adalumikizidwa ndi mavuto azaumoyo, kuphatikizapo kuledzera. Mu 2015, anthu opitilira 20,000 adamwalira ndimankhwala osokoneza bongo a opioid ku United States, malinga ndi American Society of Addiction Medicine.

Muyenera kuwerenga mosamala zambiri zomwe zili muzogulitsazo musanayambe kumwa mankhwala ndi oxycodone. Ingotenga mlingo wanu woyenera. Lumikizanani ndi dokotala wanu ngati muli ndi mafunso kapena nkhawa.