Insulin-Like Growth Factor (IGF): Zomwe Muyenera Kudziwa

Zamkati

• Kodi pali kulumikizana kotani pakati pa matenda ashuga ndi IGF?
• Ndi kuyesa kotani komwe kulipo kwa IGF?
• Kodi mungagwiritse ntchito IGF kuchiza matenda ashuga?
• Nanga bwanji za IGF mu zowonjezera?
• Kodi malingaliro ake ndi otani?

Kodi insulini-ngati kukula factor (IGF) ndi chiyani?

IGF ndi hormone yomwe thupi lanu limapanga mwachilengedwe. Ankadziwika kuti somatomedin. IGF, yomwe imachokera pachiwindi, imakhala ngati insulin.

IGF imathandizira kuchepetsa kukula kwa mahomoni m'matumbo a pituitary. IGF imagwira ntchito ndi mahomoni okula kupititsa patsogolo kukula kwa mafupa ndi minofu. Mahomoni amenewa amakhudzanso momwe thupi lanu limagwiritsira ntchito shuga, kapena shuga. IGF ndi insulin zitha kugwirira ntchito limodzi kuti muchepetse kuthamanga kwa magazi m'magazi anu.

Kodi pali kulumikizana kotani pakati pa matenda ashuga ndi IGF?

Ngati muli ndi matenda ashuga, thupi lanu silipanga insulini yokwanira kapena simungaligwiritse ntchito moyenera. Mufunika insulini kuti muzitsuka shuga kuti mukhale ndi mphamvu. Insulin imathandizira kugawa shuga m'maselo mthupi lanu lonse ndikuchepetsa shuga m'magazi anu.

Ndi kuyesa kotani komwe kulipo kwa IGF?

Kuyezetsa magazi kosavuta kumatha kudziwa kuchuluka kwa IGF yomwe muli nayo m'magazi anu.

Madokotala amathanso kuyeserera mayesowa pamene mwana sakukula kapena kukula monga momwe amayembekezera msinkhu wawo.

Kwa achikulire, mayeserowa amatha kuchitidwa kuti aone ngati ali ndi vuto la matenda am'mimbamo kapena zotupa. Sizimaperekedwa pafupipafupi kwa anthu omwe ali ndi matenda ashuga.

IGF imayesedwa mu nanograms pa mamililita (ng / mL). Masamba abwinobwino ndi awa:

• 182-780 ng / mL kwa anthu azaka 16-24
• 114-492 ng / mL ya anthu azaka 25-39
• 90-360 ng / mL ya anthu azaka 40-54
• 71-290 ng / mL ya anthu 55 ndi kupitirira

Ngati zotsatira za mayeso anu zikuwonetsa milingo yayikulu kapena yotsika kuposa momwe zimakhalira, pakhoza kukhala mafotokozedwe angapo, kuphatikiza:

• kuchuluka kwa mahomoni a chithokomiro, kapena hypothyroidism
• matenda a chiwindi
• matenda a shuga omwe samayendetsedwa bwino

Ngati milingo yanu ya IGF siyomwe ili mkati mwachizolowezi, sizitanthauza kuti pali cholakwika chilichonse. Dokotala wanu adzakufotokozerani kutengera chidziwitso chambiri.

Magulu apamwamba a IGF atha kukulitsa chiopsezo cha khansa yamtundu, yamabele, komanso ya prostate, ngakhale palibe kafukufuku waposachedwa yemwe awunikiranso kulumikizanaku. Insulini yomwe anthu amagwiritsa ntchito pochiza matenda amtundu wa 2 amathanso kuwonjezera chiopsezo cha khansa zina.

Kodi mungagwiritse ntchito IGF kuchiza matenda ashuga?

Mecasermin (Increlex) ndi mtundu wa IGF. Ndi mankhwala omwe madokotala amagwiritsa ntchito pochiza kukula kwa ana. Chimodzi mwazotsatira zoyipa za mecasermin ndi hypoglycemia. Ngati muli ndi hypoglycemia, zikutanthauza kuti muli ndi magazi ochepa.

Kafukufuku akuwonetsa kuti IGF imatha kupondereza mtundu wa 1 shuga m'magulu. Mu mtundu wa 1 shuga, chitetezo cha mthupi chimadzitembenukira chokha, ndikulimbana ndi maselo a beta m'matenda omwe amatulutsa insulin. IGF ikhoza kuteteza kumbuyo kwa thupi lomwe.

Kafukufuku wina wasonyeza kuti chithandizo ndi IGF chitha kuthandiza kuwongolera matenda ashuga. Sizinapangidwe kuti zithandizire matenda ashuga chifukwa cha zovuta zoyipa, kuphatikiza:

• kutupa kwa mitsempha yamawonedwe
• kuwonanso matenda
• kupweteka kwa minofu
• kupweteka pamodzi

Ngakhale kafukufuku wolonjeza alipo, ubale pakati pa IGF ndi matenda ashuga ndiwovuta. Kafukufuku wowonjezereka amafunikira asanagwiritse ntchito IGF kuchiza matenda ovutawa.

Nanga bwanji za IGF mu zowonjezera?

Zakudya zowonjezera zosiyanasiyana zimakhala ndi mahomoni okula, kuphatikiza IGF. Makampani amawalimbikitsa kuthana ndi ukalamba, mphamvu, komanso kukonza chitetezo chamthupi, mwazinthu zina.

Anti-Doping Agency yaku America ichenjeza kuti zinthu zomwe akuti zili ndi IGF-1 mwina sizingatero. Itha kusungunuka kapena mankhwalawo atha kukhala ndi zinthu zina zomwe zitha kukhala zowononga. Anthu amathanso kugwiritsa ntchito molakwika IGF-1.

Zotsatira zoyipa za IGF-1 zitha kukhala zofanana ndi za mahomoni ena okula. Izi zimaphatikizapo kuchulukana kwa minofu yamthupi, yotchedwa acromegaly, komanso kuwonongeka kwa zimfundo, chiwindi, ndi mtima.

IGF-1 imatha kupangitsa kuti magazi m'magazi anu atsike. Ngati muli ndi matenda ashuga, kapena ngakhale mulibe, ndikofunikira kuti mufunsane ndi dokotala musanadye zowonjezera zomwe zili ndi mahomoni okula.

Kodi malingaliro ake ndi otani?

Kafukufuku akuwonetsa kuti IGF ikhoza kulumikizidwa ndi matenda ashuga, koma anthu samamvetsetsa kulumikizana. Mutha kuchiza matenda anu ashuga ndi IGF, koma izi ndizoyeserabe.

Lankhulani ndi dokotala musanatenge IGF kapena musanayesere zowonjezera zilizonse, ndipo musasinthe dongosolo lanu lazachipatala osalankhula ndi dokotala. Matenda a shuga ndi matenda ovuta, ndipo amatha kuyambitsa mavuto ambiri ngati simupeza chithandizo chake.