Immunoglobulin A (IgA): chomwe chiri ndi tanthauzo lake ikakhala pamwamba

Zamkati

• IgA ya chiyani
• Zitha kukhala zotani IgA
• Zitha kukhala zotani IgA

Immunoglobulin A, yomwe imadziwika kuti IgA, ndi puloteni yomwe imapezeka m'matumbo, makamaka m'mapapo ndi m'mimba, kuphatikiza pakupezeka mkaka wa m'mawere, womwe umatha kupatsira mwana mukamayamwitsa ndikulimbikitsa kukula chitetezo cha mthupi.

Ma immunoglobulin awa ndi omwe ali ndi ntchito yayikulu yoteteza chamoyo, chifukwa chake, atakhala ochepa, amatha kuthandizira kukulitsa matenda, omwe amayenera kuzindikiritsidwa ndikuchiritsidwa malinga ndi malangizo a dokotala.

IgA ya chiyani

Ntchito yayikulu ya IgA ndikuteteza thupi kumatenda ndipo imatha kupezeka poyamwitsa, momwe ma immunoglobulins a amayi amapatsira mwanayo. Puloteni iyi imatha kugawidwa m'magulu awiri kutengera momwe imakhalira ndi mawonekedwe ake, ndipo itha kukhala ndi ntchito zina zofunika kutetezera thupi:

• IgA 1, yomwe imapezeka makamaka mu seramu ndipo imayang'anira chitetezo cha mthupi, chifukwa imatha kuthana ndi poizoni kapena zinthu zina zopangidwa ndi tizilombo tomwe tikulowa;
• IgA 2, yomwe imapezeka m'matumbo ndipo imapezeka kuti imalumikizidwa ndi chinthu chobisalira. Mtundu uwu wa IgA umagonjetsedwa ndi mapuloteni ambiri opangidwa ndi mabakiteriya omwe amachititsa kuti maselo azitha kuwonongeka, chifukwa chake, amafanana ndi mzere woyamba wodzitetezera kumatenda opatsirana omwe amalowa m'thupi kudzera m'mimbamo.

Immunoglobulin A imatha kupezeka ndi misozi, malovu ndi mkaka wa m'mawere, kuphatikiza popezeka m'mayendedwe am'thupi, m'mimba komanso kupuma, kuteteza makinawa kumatenda.

Onaninso momwe chitetezo chamthupi chimagwirira ntchito.

Zitha kukhala zotani IgA

Kuwonjezeka kwa IgA kumatha kuchitika ngati pali kusintha kwa mamina, makamaka m'matumbo ndi m'mapapo mwanga, chifukwa immunoglobulin imapezeka makamaka pamalopo. Chifukwa chake, kuchuluka kwa IgA kumatha kuwonjezeka ngati munthu ali ndi matenda opatsirana kapena matumbo komanso chiwindi cha chiwindi, mwachitsanzo, kuwonjezera pamenepo pakhoza kukhala zosintha pakakhala matenda pakhungu kapena impso.

Ndikofunikira kuti mayeso ena achitike kuti adziwe chomwe chimayambitsa IgA chifukwa chake, chithandizo choyenera kwambiri chitha kuyambitsidwa.

Zitha kukhala zotani IgA

Kuchepa kwa kuchuluka kwa IgA komwe kumazungulira nthawi zambiri kumakhala majini ndipo sikumayambitsa kukula kwa zizindikilo zokhudzana ndi kusinthaku, kuwonedwa ngati kusowa pamene kuchuluka kwa immunoglobulin sikutsika 5 mg / dL m'magazi.

Komabe, kuchuluka kocheperako kwa ma immunoglobulin oyenda mthupi kumatha kuthandizira kukulira matenda, popeza mamvekedwe a mucous alibe chitetezo. Chifukwa chake, kuwonjezera pakuchepetsedwa chifukwa cha majini, kuchepa kwa IgA amathanso kukhalapo ngati:

• Kusintha kwamatenda;
• Mphumu;
• Ziwengo kupuma;
• Enaake fibrosis;
• Khansa ya m'magazi;
• Matenda otsekula m'mimba;
• Matenda a Malabsorption;
• Ana obadwa kumene omwe ali ndi rubella;
• Anthu omwe adalowetsedwa m'mafupa;
• Ana omwe ali ndi kachilombo ka Epstein-Barr.

Nthawi zambiri, IgA ikachepa, thupi limayesetsa kulipirira kuchepa uku poonjezera kupanga IgM ndi IgG kuti athane ndi matendawa ndikuteteza thupi. Ndikofunikira kuti, kuwonjezera pamiyeso ya IgA, IgM ndi IgG, mayeso oyesedwa amachitika kuti adziwe chomwe chasintha ndikusintha, motero, kuyambitsa chithandizo choyenera kwambiri. Dziwani zambiri za IgM ndi IgG.