Chilichonse Chimene Muyenera Kudziwa Zokhudza Katemera wa COVID-19 wa Johnson & Johnson

Zamkati

• Kodi katemera wa Johnson & Johnson COVID-19 amagwira ntchito bwanji?
• Kodi katemera wa Johnson & Johnson COVID-19 amagwira ntchito bwanji?
• Zambiri za Matenda a COVID-19 ndi Imfa
• COVID-19 Zosiyanasiyana
• Kodi ndi mankhwala angati a katemera a Johnson & Johnson COVID-19 omwe mukufuna?
• Kodi katemera wa Johnson & Johnson amakhudza bwanji kufalikira kwa COVID-19?
• Onaninso za

Pa february 26, komiti yolangizira katemera ya FDA idavota mogwirizana kuti ivomereze katemera wa Johnson & Johnson wa COVID-19 kuti agwiritsidwe ntchito mwadzidzidzi. Izi zikutanthauza kuti katemera - yemwe amafunikira mlingo umodzi wokha - atha kukhala okonzeka kugwiritsidwa ntchito ku US kumapeto kwa Marichi, malinga ndi Center for Infectious Disease Research and Policy (CIDRAP).

Koma, kodi katemera wa COVID-19 wa Johnson & Johnson ndi othandiza motani? Ndipo zikufanana bwanji ndi katemera wina wa COVID-19 wochokera ku Pfizer ndi Moderna? Izi ndi zomwe muyenera kudziwa.

Kodi katemera wa Johnson & Johnson COVID-19 amagwira ntchito bwanji?

Ngati mumadziwa bwino katemera wa COVID-19 wopangidwa ndi Pfizer ndi Moderna, ndiye kuti mwina mukudziwa kuti onse ndi katemera wa mRNA. Izi zikutanthauza kuti amagwira ntchito ndikulemba gawo la kachilombo koyambitsa kachilombo ka SARS-CoV-2 (gawo la kachilomboka kamene kamadziphatika ku maselo a thupi lanu) ndikugwiritsa ntchito zidutswazo kuti zitha kuyambitsa chitetezo chamthupi mthupi lanu kuti apange asilikali olimbana ndi kachilomboka. (Onani: Kodi Katemera wa COVID-19 Ndi Wogwira Ntchito Motani?)

Katemera wa Johnson & Johnson amagwira ntchito mosiyana. Chifukwa chimodzi, si katemera wa mRNA. Ndi katemera wa adenovector, zomwe zikutanthauza kuti imagwiritsa ntchito kachilombo koyambitsa matendawa (pamenepa, adenovirus, yomwe imayambitsa chimfine) ngati vekitala yoperekera mapuloteni (pamenepa, mapuloteni oyipa ochokera ku SARS-CoV-2) omwe thupi lanu kuzindikira kuti ndiwopseza ndikupanga ma antibodies motsutsana nawo, atero a Brittany Busse, MD, oyang'anira othandizira azachipatala ku WorkCare.

Tsopano, mwina mungakhale mukuganiza ngati kuyika "kachilombo kosagwira ntchito" mthupi lanu kungakudwalitseni mosazindikira, koma sikungatero. "Kachilombo koyambitsa matenda sikungathe kubwereza kapena kukupangitsani kudwala," atero Abisola Olulade, MD, dotolo wovomerezeka wapabanja ku Sharp Rees-Stealy Medical Group. M'malo mwake, adenovirus mu katemera wa COVID-19 wa Johnson & Johnson amangogwira ntchito ngati chonyamulira (kapena "vekitala") ya jini ya protein ya SARS-CoV-2 m'maselo anu, ndikupangitsa kuti maselowa apange ma geni amenewo, akufotokoza. Ganizirani za jini ya spike protein ngati malangizo amomwe thupi lanu lingamenyere SARS-CoV-2, akuwonjezera Dr. Olulade. "Mapuloteni amtunduwu amatha kuzindikirika ndi chitetezo cha mthupi lanu ndikupangitsa kuti mupange ma antibodies omwe angateteze ku COVID," akufotokoza. (FYI: Chiwombankhanga chimagwira chimodzimodzi.)

Ngakhale ukadaulo wa katemerayu ndi wosiyana ndi wa Pfizer ndi Moderna, si nkhani yaposachedwa. Katemera wa COVID wa Oxford ndi AstraZeneca - omwe adavomerezedwa kuti agwiritsidwe ntchito ku EU ndi UK mu Januware (a FDA pakadali pano akuyembekezera zambiri kuchokera kuzachipatala cha AstraZeneca asanakambirane chilolezo cha US, a New York Times malipoti) - amagwiritsa ntchito ukadaulo wofanana wa adenovirus. Johnson & Johnson adagwiritsanso ntchito ukadaulo kupanga katemera wake wa Ebola, yemwe wawonetsedwa kuti ndi wotetezeka komanso wogwira mtima popanga chitetezo chamthupi m'thupi.

Kodi katemera wa Johnson & Johnson COVID-19 amagwira ntchito bwanji?

Pakuyesa kwakukulu kwachipatala kwa anthu pafupifupi 44,000, katemera wa Johnson & Johnson wa COVID-19 adawonetsedwa kuti ndiwothandiza 66 peresenti popewa zolimbitsa thupi (zomwe zimatanthauzidwa kukhala ndi chimodzi kapena zingapo za COVID-19) ku COVID-19 (yodziwika ndi kuloledwa ku ICU, kulephera kupuma, kapena kulephera kwa ziwalo, mwa zina) masiku 28 atalandira katemera, malinga ndi zomwe atolankhani atulutsa kuchokera ku kampaniyo. (Zambiri "zidzatumizidwa ku magazini yowunikiridwa ndi anzawo m'masabata akudzawa," atero atolankhani.)

Johnson & Johnson adanenanso kuti katemera wake wachitetezo ku COVID yochepa anali 72% ku US, 66% ku Latin America, ndi 57% ku South Africa (komwe, kuphatikiza, kumakupatsirani kuchuluka kwa magwiridwe antchito 66%) . Ngati ziwerengerozi zikuwoneka ngati zosafunikira, tiyenera kudziwa kuti, poyerekeza, chimfine chimangokhala 40 mpaka 60% yothandiza kuteteza thupi ku fuluwenza, komabe imathandizanso pakuchepetsa kulumikizana ndi chimfine, akuti Dr. Olulade. (Zokhudzana: Kodi Flu Shot Ingakutetezeni ku Coronavirus?)

Zambiri za Matenda a COVID-19 ndi Imfa

Poyamba, mphamvu ya katemera wa Johnson & Johnson yokwanira 66% ingawoneke ngati yotsika, makamaka mukayifanizira ndi kuchuluka kwa mphamvu kuchokera ku Moderna (94.5% ogwira ntchito) ndi Pfizer ("opitilira 90% ogwira ntchito," malinga ndi kampaniyo). Koma ngati mukumba mozama, zambiri za Johnson & Johnson chitani kuwonetsa zotsatira zabwino kwambiri, makamaka zikafika pamilandu yoopsa kwambiri ya COVID-19.

Katemera aliyense anali 85% yothandiza poletsa zovuta za COVID-19, malinga ndi zomwe atolankhani a Johnson & Johnson adalemba. M'malo mwake, kampaniyo idazindikira kuti katemera wake adawonetsa "chitetezo chathunthu kuchipatala chokhudzana ndi COVID ndikumwalira" masiku 28 atalandira katemera, "popanda milandu" ya kuchipatala yokhudzana ndi COVID kapena kufa pakati pa omwe adalandira katemera wa Johnson & Johnson.

Pankhani ya zoyipa, Johnson & Johnson adati katemera wake wa COVID "amalekerera bwino" kwa onse omwe adachita nawo mayesowo. Zotsatira zoyambirira za kampaniyo zikusonyeza kuti katemerayu atha kuyambitsa "zovuta zochepa zomwe zimakhudzana ndi katemera," kuphatikiza kutopa, kupweteka mutu, kupweteka kwa minofu, komanso kupweteka kwa tsamba la jekeseni.

COVID-19 Zosiyanasiyana

Mosiyana ndi kafukufuku wa Pfizer ndi Moderna, mayeso a katemera a Johnson & Johnson akuphatikiza zotsatira m'malo ambiri - kuphatikiza omwe awona posachedwa milandu ya COVID yoyambitsidwa ndimatenda omwe akutuluka. Dr. Inde, ofufuza tsopano akuyang'ana momwe angagwiritsire ntchito zonse Katemera wa COVID-19 atha kukhala oteteza thupi ku mitundu ingapo ya COVID-19. Pakadali pano, Dr. Busse akuti kusiyanasiyana kwa UK "sikuyenera kukhala vuto la katemera wa COVID." Komabe, akuwonjezera, pamenepo ndi kuyerekezera kuti mitundu ya COVID yaku South Africa ndi Brazil itha "kusintha momwe ma antibodies amalumikizirana ndi kachilomboka" ndikupangitsa kuti ma antibodies oteteza "asamagwire bwino ntchito." (Zogwirizana: Chifukwa Chiyani Makina Atsopano a COVID-19 Akufalikira Mwachangu?)

Izi zati, ngakhale katemera sangalepheretse matenda a COVID-19, zikuwoneka kuti amathandiza anthu kupewa kachilombo koyipa kwambiri. "Izi zikutanthawuzanso kuti ili ndi mphamvu yochepetsera katundu pachipatala chathu cholemedwa kwambiri ndipo zimatifikitsa pafupi ndi kuwalako kumapeto kwa msewu," akutero Dr. Olulade.

"Ndikofunikanso kukumbukira kuti tikamapereka anthu katemera mwachangu, mavutowo amafunika kusintha ndikusinthanso," akuwonjezera motero Dr. Olulade. "Ndiye chifukwa chake tiyenera kupeza aliyense [katemera] posachedwa."

Kodi ndi mankhwala angati a katemera a Johnson & Johnson COVID-19 omwe mukufuna?

Kupatula pa kugwira ntchito kwa katemera wokha, akatswiri akuti katemera wa COVID wa Johnson & Johnson akulonjezanso chifukwa amangofunika kuwombera kamodzi, pomwe katemera wa Pfizer ndi Moderna aliyense amafuna kuwombera kawiri patadutsa milungu ingapo.

"Izi zitha kukhala zosintha masewera," akutero Dr. Olulade. "Tikuwona kuti odwala ena, mwatsoka, sabweranso kuti adzalandire mlingo wawo wachiwiri," kotero kuti njira imodzi yokhayo imatha kutanthauzira katemera wambiri.

Phindu lina lalikulu la katemera wa Johnson & Johnson's COVID? Mlingo wake mwachiwonekere ndi wosavuta kusunga ndi kugawa kuposa katemera wa Pfizer ndi Moderna, chifukwa chogwiritsa ntchito ukadaulo wa katemera wa adenovector wa J & J. Dr. "Katemera wa Johnson & Johnson amakhala wokhazikika mufiriji kwa miyezi itatu, zomwe zimapangitsa kuti zikhale zosavuta kutumiza ndikugawa kwa omwe akuzifuna."

Kodi katemera wa Johnson & Johnson amakhudza bwanji kufalikira kwa COVID-19?

"Kwatsala pang'ono kunena," atero a Prabhjot Singh, MD, Ph.D., mlangizi wamkulu wazachipatala ndi sayansi wa CV19 CheckUp, chida chapaintaneti chomwe chimathandiza kuwunika kuopsa kwa COVID-19. Izo zimapita kwa zonse a katemera wa COVID-19 omwe tawonapo mpaka pano BTW, osati Johnson & Johnson okha, akutero Dr. Singh. "Kafukufuku woyambirira akuwonetsa kuti chiopsezo chotenga kachilomboka chiyenera kuchepa pambuyo polandira katemera, koma yankho lotsimikizika limafuna kafukufuku wokhazikika," akufotokoza motero.

Popeza zotsatira za katemera pa kufala kwa COVID sizikudziwikabe, ndikofunikira kwambiri kuti mupitirize kuvala masks ndikukhala kutali ndi anthu omwe ali kunja kwa nyumba yanu, akutero Dr. Olulade. (Yembekezani, kodi mukuyenera kukhala mukuphimba kawiri kuti muteteze ku COVID-19?)

Mfundo yofunika: Zonse katemera ameneyu akuwoneka kuti akuteteza kwambiri ku COVID-19, yomwe ndiyabwino. Chikhalirechobe, “katemera sali chilolezo cha kulepheretsa chisamaliro chanu,” akufotokoza motero Dr. Olulade. "Tiyenera kuganizira mopanda dyera za thanzi ndi moyo wa ena omwe sanalandirebe katemera ndipo mwina alibe chitetezo ku COVID."

Zomwe zili munkhaniyi ndizolondola monga nthawi yolemba. Pomwe zosintha za coronavirus COVID-19 zikupitilizabe kusintha, ndizotheka kuti zina ndi zina zomwe zanenedwa m'nkhaniyi zasintha kuyambira pomwe zidasindikizidwa koyamba. Tikukulimbikitsani kuti mumayang'anitsitsa pafupipafupi ndi zinthu monga CDC, WHO, ndi dipatimenti yazaumoyo yakwanuko kuti mumve zambiri zamtunduwu komanso malingaliro awo.

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