Mlembi: Charles Brown
Tsiku La Chilengedwe: 1 Febuluwale 2021
Sinthani Tsiku: 21 Novembala 2024
Anonim
#PAMIDRONATO
Kanema: #PAMIDRONATO

Zamkati

Pamidronate ndi mankhwala opangira anti-hypercalcemic omwe amadziwika kuti Aredia.

Mankhwalawa omwe amagwiritsidwa ntchito jakisoni amawonetsedwa pa matenda a Paget, osteolysis popeza imaletsa kuyambiranso kwa mafupa kudzera munjira zingapo, kuchepetsa zizindikilo za matenda.

Zisonyezero za Pamidronate

Matenda a Paget; hypercalcemia (yogwirizana ndi neoplasia); osteolysis (yotengeka ndi chotupa cha m'mawere kapena myeloma).

Mtengo wa Pamidronato

Mtengo wa mankhwalawo sunapezeke.

Zotsatira zoyipa za Pamidronate

Kuchepetsa potaziyamu wamagazi; kuchepa kwa phosphates m'magazi; zotupa pakhungu; kuumitsa; kupweteka; kugwedeza; kutupa; kutupa mtsempha; malungo ochepa.

Matenda a Paget: kuthamanga kwa magazi; kupweteka kwa mafupa; mutu; kupweteka pamodzi.

Matenda a osteolysis: kuchepa magazi; kusowa chilakolako; kutopa; kuvuta kupuma kudzimbidwa; kuwawa kwam'mimba; kupweteka pamodzi; chifuwa; mutu.


Zotsutsana za Pamidronate

Kuopsa kwa Mimba C; kuyamwitsa: odwala omwe ali ndi ziwengo ku bisphosphonates; Kukhwimitsa magwiridwe antchito pazinthu zilizonse.

Momwe mungagwiritsire ntchito Pamidronate

Ntchito m'jekeseni

Akuluakulu

  • Matenda a Hypercalcemia: 60 mg yoperekedwa kwa maola 4 mpaka 24 (hypercalcemia - coral calcium yolondola kwambiri kuposa 13.5 mg / dL - ingafune 90 mg yoperekedwa maola 24).
  • Odwala omwe ali ndi vuto la impso kapena ochepa hypercalcemia: 60 mg kutumikiridwa pa 4 kuti 24 maola.

Mungodziwiratu: ngati hypercalcemia ibwereranso, chithandizo chatsopano chitha kuganiziridwa ngati masiku 7 atadutsa.

  • Matenda a Paget a fupa: Chiwerengero chonse cha 90 mpaka 180 mg pa nthawi ya chithandizo; Mlingo wonse ungaperekedwe kwa 30 mg tsiku lililonse kwa masiku 3 motsatizana kapena 30 mg kamodzi pamlungu kwa milungu 6. Mlingo wa makonzedwe nthawi zonse ndi 15 mg pa ola limodzi.
  • Osteolysis yotulutsa chotupa (mu khansa ya m'mawere): 90 mg imayendetsedwa kuposa maola awiri, milungu itatu kapena inayi iliyonse; (mu myeloma): 90 mg yoyendetsedwa kuposa maola 2, kamodzi pamwezi.

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