Matenda a Goodpasture: ndi chiyani, zizindikiro, zoyambitsa ndi chithandizo

Zamkati

• Zizindikiro zazikulu
• Momwe mungatsimikizire matendawa
• Zomwe zingayambitse
• Momwe mankhwalawa amachitikira

Goodpasture Syndrome ndi matenda osowa mthupi okhaokha, momwe chitetezo chamthupi chimagwirira impso ndi mapapo, makamaka zimayambitsa zizindikilo monga kutsokomola kwamagazi, kupuma movutikira komanso kutaya magazi mkodzo.

Izi zimachitika chifukwa cha kupezeka kwa ma antibodies omwe amalimbana ndi maselo a impso ndi mapapo. Zina mwazinthu zomwe zikuwoneka kuti zikuwonjezera chiopsezo chotenga matendawa ndi: kukhala ndi mbiri ya matendawa komanso kusuta, kukhala ndi matenda opatsirana mobwerezabwereza ndikuwonetsedwa ndi zinthu monga methane kapena propane, mwachitsanzo.

Chithandizochi chimachokera pakugwiritsa ntchito mankhwala monga immunosuppressants ndi corticosteroids, koma pamavuto akulu kwambiri, plasmapheresis kapena hemodialysis itha kukhala yofunikira.

Zizindikiro zazikulu

Zizindikiro zazikulu za Goodpasture Syndrome ndi izi:

• Kutopa kwambiri;
• Kutsokomola magazi;
• Kupuma kovuta;
• Ululu mukamapuma;
• Kuchuluka kwa urea m'magazi;
• Kukhalapo kwa magazi ndi / kapena thovu mu mkodzo;
• Kuwotcha pokodza.

Zizindikiro zikayamba, ndikulimbikitsidwa kuti mupite kuchipatala mwachangu kukayezetsa ndikuwonetsa chithandizo chofunikira kwambiri, chifukwa zizindikilozo zimatha kukulira ngati matendawa sakuchiritsidwa msanga.

Kuphatikiza apo, matenda ena atha kukhala ndi zizindikiro zofananira ndi matendawa, monga Wegener granulomatosis, yomwe imapangitsa kuti matenda azivuta. Dziwani zizindikiritso ndi momwe mungachiritsire Wegener's granulomatosis.

Momwe mungatsimikizire matendawa

Kuti adziwe za Goodpasture's syndrome, adotolo awunika mbiri yaumoyo wanu komanso kutalika kwa zomwe mukudwala. Kenako, adotolo amatha kuyitanitsa mayeso, monga kuyesa magazi ndi mkodzo, kuti adziwe ma antibodies omwe amapangidwa ndi thupi omwe amayambitsa matenda a Goodpasture.

monga kupsyinjika kwa impso, komwe ndiko kuchotsa gawo laling'ono la impso, kuti muwone ngati pali maselo omwe amayambitsa matenda a Goodpasture.

Kuphatikiza apo, adotolo amathanso kuyitanitsa mayeso ena, monga kupsyinjika kwa impso, komwe kumakhala kuchotsa gawo laling'ono la impso lomwe liziwunikidwa mu labotale, kuti muwone ngati pali maselo omwe amayambitsa matenda a Goodpasture.

Ma X-ray ndi ma CT scan amathanso kuyitanidwa ndi dokotala kuti azindikire kuwonongeka kwamapapu. Onani zambiri zamomwe kompyuta tomography imagwiridwira.

Zomwe zingayambitse

Zomwe zimayambitsa matenda a Goodpasture zimachitika chifukwa cha ma anti-GBM antibodies omwe amalimbana ndi NC-1 gawo la mtundu wa IV collagen m'maselo a impso ndi m'mapapo.

Matendawa amawoneka ofala kwambiri mwa amuna kuposa akazi, azaka zapakati pa 20 mpaka 30, komanso mwa anthu omwe ali ndi khungu lowala. Kuphatikiza apo, kupezeka kwa mankhwala monga mankhwala ophera tizilombo, utsi wa ndudu, ndi matenda omwe amayamba chifukwa cha mavairasi ndi zina mwazinthu zomwe zimawoneka kuti zimawonjezera chiopsezo chokhala ndi matendawa, chifukwa zimatha kupangitsa kuti chitetezo chamthupi chiwononge mapapo ndi mapapo.

Momwe mankhwalawa amachitikira

Chithandizo cha Goodpasture's Syndrome chimachitika kuchipatala ndipo chimatengera kugwiritsa ntchito mankhwala osokoneza bongo komanso ma corticosteroids, omwe amateteza maselo amthupi kuwononga impso ndi mapapo.

Nthawi zina, mankhwala a plasmapheresis amawonetsedwa, yomwe ndi njira yomwe imasefa magazi ndikulekanitsa ma antibodies omwe ndi owopsa ku impso ndi mapapo. Ngati impso zakhudzidwa kwambiri, hemodialysis kapena kumuika impso kungafunike. Kumvetsetsa bwino chomwe plasmapheresis ndi momwe zimachitikira.