Pemphigus Foliaceus

Zamkati

• Zizindikiro zake ndi ziti?
• Zimayambitsa ndi chiyani?
• Kodi njira zamankhwala ndi ziti?
• Zovuta zake ndi ziti?
• Nthawi yoti muwonane ndi dokotala
• Chiwonetsero

Chidule

Pemphigus foliaceus ndi matenda omwe amachititsa kuti matuza ayambe kupanga pakhungu lanu. Ndi mbali ya banja losaoneka khungu lotchedwa pemphigus lomwe limatulutsa matuza kapena zilonda pakhungu, mkamwa, kapena kumaliseche.

Pali mitundu iwiri ikuluikulu ya pemphigus:

• pemphigus vulgaris
• pemphigus foliaceus

Pemphigus vulgaris ndi mtundu wofala kwambiri komanso woopsa kwambiri. Pemphigus vulgaris imakhudza khungu osati khungu kokha. Zimayambitsa matuza opweteka pakamwa panu, pakhungu lanu, komanso kumaliseche kwanu.

Pemphigus foliaceus imapangitsa matuza ang'onoang'ono kupanga pamwamba pamutu ndi nkhope. Ndiwofatsa kuposa pemphigus vulgaris.

Pemphigus erythematosus ndi mtundu wa pemphigus foliaceus womwe umapangitsa matuza kuti apange okha pamaso. Zimakhudza anthu omwe ali ndi lupus.

Zizindikiro zake ndi ziti?

Pemphigus foliaceus imayambitsa matuza odzaza madzi pakhungu lanu, nthawi zambiri pachifuwa, kumbuyo, ndi pamapewa. Poyamba matuza ndi ochepa, koma pang'onopang'ono amakula ndikuwonjezeka. Pamapeto pake amatha kuphimba thupi lanu lonse, nkhope yanu, ndi khungu lanu.

Matuza amatseguka mosavuta. Madzi amatha kutuluka kuchokera kwa iwo. Mukapukuta khungu lanu, gawo lonse lathunthu limatha kusiyanasiyana kuchokera pansi kenako ndikutsuka papepala.

Matuza atseguka, amatha kupanga zilonda. Zilondazo zimakula ndikutumphuka.

Ngakhale pemphigus foliaceus nthawi zambiri siyopweteka, mutha kumva kupweteka kapena kutentha m'dera la matuza. Matuza amathanso kuyabwa.

Zimayambitsa ndi chiyani?

Pemphigus foliaceus ndimatenda amthupi okha. Nthawi zambiri, chitetezo chamthupi chimatulutsa mapuloteni otchedwa ma antibodies kuti athane ndi adani akunja monga mabakiteriya ndi ma virus. Kwa anthu omwe ali ndi matenda omwe amadzichitira okhaokha, ma antibodies amalakwitsa molakwika mthupi mwawo.

Mukakhala ndi pemphigus foliaceus, ma antibodies amamangirira puloteni m'mbali yakunja ya khungu lanu, yotchedwa epidermis. M'mbali imeneyi ya khungu mumakhala maselo otchedwa keratinocytes. Maselowa amapanga protein - keratin - yomwe imapanga khungu lanu ndikuthandizira. Ma antibodies akamenyana ndi keratinocytes, amasiyana.Madzi amadzaza malo omwe amasiya. Timadziti timatulutsa matuza.

Madokotala sakudziwa chomwe chimayambitsa pemphigus foliaceus. Zinthu zochepa zomwe zingakulitse mwayi wanu wopeza izi, kuphatikizapo:

• kukhala ndi abale ndi pemphigus foliaceus
• kuwonetseredwa padzuwa
• kulumidwa ndi tizilombo (m'mayiko a South America)

Mankhwala angapo amalumikizananso ndi pemphigus foliaceus, kuphatikiza:

• penicillamine (Cuprimine), amagwiritsidwa ntchito pochiza matenda a Wilson
• angiotensin amatembenuza ma enzyme inhibitors monga captopril (Capoten) ndi enalapril (Vasotec), omwe amagwiritsidwa ntchito pochizira kuthamanga kwa magazi
• angiotensin-II receptor blockers monga candesartan (Atacand), omwe amagwiritsidwa ntchito pochiza kuthamanga kwa magazi
• maantibayotiki monga rifampicin (Rifadin), omwe amagwiritsidwa ntchito pochiza matenda a bakiteriya
• mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs)

Pemphigus foliaceus imatha kuyambira zaka zilizonse, koma nthawi zambiri imakhudza anthu azaka zapakati pa 50 ndi 60. Anthu omwe ali achiyuda ali pachiwopsezo chachikulu cha pemphigus vulgaris.

Kodi njira zamankhwala ndi ziti?

Cholinga cha chithandizo ndikuchotsa matuza ndikuchiritsa matuza omwe muli nawo kale. Dokotala wanu akhoza kukupatsani zonona za corticosteroid kapena mapiritsi. Mankhwalawa amabweretsa kutupa mthupi lanu. Kuchuluka kwa corticosteroids kumatha kuyambitsa zovuta zina monga kuchuluka kwa shuga m'magazi, kunenepa, komanso kutaya mafupa.

Mankhwala ena omwe amagwiritsidwa ntchito pochizira pemphigus foliaceus ndi awa:

• Kupondereza chitetezo cha mthupi. Mankhwala monga azathioprine (Imuran) ndi mycophenolate mofetil (CellCept) amateteza chitetezo cha mthupi lanu kuti lisalimbane ndi minyewa ya thupi lanu. Chotsatira chachikulu cha mankhwalawa ndi chiopsezo chowonjezeka cha matenda.
• Maantibayotiki, mankhwala ochepetsa mphamvu ya kachilombo, ndi mankhwala osokoneza bongo. Izi zitha kuteteza matuza kuti asatengeke ngati atseguka.

Ngati matuza ataphimba khungu lanu, mungafunikire kukhala mchipatala kuti mukalandire chithandizo. Madokotala ndi anamwino amatsuka ndikumanga zilonda zanu kuti mupewe matenda. Mutha kupeza madzi kuti mutenge zomwe mwataya ndi zilonda.

Zovuta zake ndi ziti?

Matuza omwe amatseguka atha kutenga kachilomboka. Ngati mabakiteriya alowa m'magazi anu, amatha kuyambitsa matenda owopsa omwe amatchedwa sepsis.

Nthawi yoti muwonane ndi dokotala

Onani dokotala wanu ngati muli ndi matuza pakhungu lanu, makamaka ngati atseguka.

Dokotala wanu adzafunsa za matenda anu ndikuwunika khungu lanu. Amatha kuchotsa chidutswa cha chithuza ndikuchitumiza ku labu kukayezetsa. Izi zimatchedwa biopsy khungu.

Muthanso kuyesa magazi kuti mupeze ma antibodies omwe chitetezo chanu chamthupi chimatulutsa mukakhala ndi pemphigus foliaceus.

Ngati mwapezeka kuti muli ndi pemphigus kale, muyenera kulumikizana ndi dokotala mukayamba:

• matuza atsopano kapena zilonda
• kufalikira kofulumira kwa chiwerengero cha zilonda
• malungo
• kufiira kapena kutupa
• kuzizira
• kufooka kapena kupweteka kwa minofu kapena mafupa

Chiwonetsero

Anthu ena amachira popanda chithandizo. Ena atha kukhala ndi matendawa kwazaka zambiri. Mungafunike kumwa mankhwala kwa zaka zambiri kuti matuza asabwererenso.

Ngati mankhwala adayambitsa pemphigus foliaceus, kusiya mankhwalawa kumatha kutsirizitsa matendawa.