Prolactin mwa amuna: zoyambitsa, zizindikiro ndi chithandizo

Zamkati

• Zizindikiro za kuchuluka kwa prolactin mwa amuna
• Zimayambitsa kuchuluka kwa prolactin mwa amuna
• Kufufuza kwa Prolactin kwa amuna
• Chithandizo chotsitsa prolactin

Prolactin ndi mahomoni omwe, ngakhale ali ndi udindo wopanga mkaka wa m'mawere, mwa amuna, ali ndi ntchito zina, monga kupumula thupi atafika pachimake, mwachitsanzo.

Magulu abwinobwino a prolactin mwa amuna amakhala ochepera 10 mpaka 15 ng / mL, koma amatha kufikira kwambiri chifukwa chodwala, kugwiritsa ntchito mankhwala omwe amakhala ndi mbali iyi, kapena chifukwa cha chotupa muubongo.

Zizindikiro za kuchuluka kwa prolactin mwa amuna

Kutulutsa mkaka kudzera munsonga yamunthuyo, kumatha kupezeka nthawi zina, ndipo kumatha kuwonedwa adotolo atakakamira mdera lakuda la bere. Zizindikiro zina ndi izi:

• Kuchepetsa chilakolako chogonana;
• Kugonana;
• Kuchepetsa umuna;
• Kuchepetsa magulu a testosterone;
• Kukula kwa m'mawere ndi kutsekemera kwa mkaka sizingachitike kawirikawiri.

Zizindikiro zina zosafala kwambiri ndikumva mutu, kusintha kwa masomphenya chifukwa cha kufooka kwa mitsempha ya optic komanso kufooka kwa mitsempha ya cranial, yomwe imakonda kwambiri amuna kuposa akazi, mwina chifukwa mwa amuna zotupazo nthawi zambiri zimakhala zazikulu kuposa azimayi.

Zimayambitsa kuchuluka kwa prolactin mwa amuna

Zitsanzo zina za mankhwala omwe amatsogolera kuwonjezeka kwa prolactin wamwamuna ndi awa:

• Mankhwala opatsirana pogonana: alprazolam, fluoxetine, paroxetine;
• Zithandizo za khunyu: haloperidol, risperidone, chlorpromazine;
• Zithandizo zam'mimba ndi mseru: cimetidine ndi ranitidine; metoclopramide, domperidone ndi cisapride;
• Mankhwala a kuthamanga kwa magazi: reserpine, verapamil, methyldopa, atenolol.

Kuphatikiza pa mankhwala, zotupa za pituitary, zotchedwa prolactinomas, zimathanso kuyambitsa kuchuluka kwa prolactin m'magazi. Matenda monga sarcoidosis, chifuwa chachikulu, aneurysm ndi radiotherapy kumutu amathanso kutenga nawo gawo, komanso kulephera kwa impso, chiwindi cha chiwindi ndi hypothyroidism.

Kufufuza kwa Prolactin kwa amuna

Amuna, ma prolactin amayenera kukhala oposa 20 ng / mL, ndipo kukwera mtengo uku, kumawonjezera chiwopsezo chotupa chotchedwa prolactinoma.

Poona kuwonjezeka kwa kuyezetsa magazi adotolo amatha kuyitanitsa mayeso azithunzi kuti athe kuyesa gland. Mayeso omwe atha kuyitanidwanso ndi ma X-ray am'mutu ndi Magnetic Resonance Imaging.

Chithandizo chotsitsa prolactin

Chithandizo chikuwonetsedwa kuti chitha kuthana ndi kusabereka, mavuto azakugonana komanso kulimbitsa mafupa. Pachifukwa ichi pangafunike kumwa mankhwala monga Bromocriptine ndi Cabergoline (lisuride, pergolide, quinagolide).

Kuchita opaleshoni kumawonetsedwa kuti kumachotsa chotupacho, pakakhala chachikulu kapena chikukula kukula. Radiotherapy sikuwonetsedwa nthawi zonse chifukwa mulingo wopambana siwokwera kwambiri.

Kuyesaku kuyenera kubwerezedwa miyezi iwiri kapena itatu iliyonse mchaka choyamba cha chithandizo, ndiyeno miyezi isanu ndi umodzi kapena chaka chilichonse, monga momwe endocrinologist imakondera.