Zithandizo zochizira ndi kupewa gout ndi zoyipa zake
Zamkati
- 1. Mankhwala osagwiritsa ntchito mankhwala opatsirana pogonana
- 2. Colchicine
- 3. Ma Corticoids
- 4. Zoletsa kupanga uric acid
- 5. Zithandizo zomwe zimawonjezera kuthetsedwa kwa uric acid
Pofuna kuchiza gout, adokotala amalimbikitsa kugwiritsa ntchito mankhwala osokoneza bongo, opweteka ndi ma corticosteroids, omwe amagwiritsidwa ntchito munthawi zovuta. Kuphatikiza apo, ena mwa mankhwalawa atha kugwiritsidwanso ntchito, poyerekeza pang'ono, popewa ziwopsezo.
Palinso zithandizo zina zomwe zimathandiza kupewa zovuta zomwe zimadza chifukwa cha matendawa, zomwe zimagwira ntchito pochepetsa uric acid kapena kulimbikitsa kuthetsedwa.
Chifukwa chake, chithandizo cha gout chiyenera kukhala payokha malinga ndi kuuma kwake, kutalika kwa mavutowo, mafupa omwe akhudzidwa, zotsutsana ndi zomwe adakumana nazo kale ndi munthuyo.
1. Mankhwala osagwiritsa ntchito mankhwala opatsirana pogonana
Mankhwala osagwiritsa ntchito zotupa monga ibuprofen, naproxen, indomethacin kapena celecoxib amagwiritsidwa ntchito kwambiri kuthana ndi ziwopsezo za gout, pamlingo waukulu, komanso kupewa kuukira kwamtsogolo pamlingo wochepa.
Komabe, mankhwalawa amatha kuyambitsa mavuto m'mimba, monga kupweteka m'mimba, kutuluka magazi ndi zilonda, makamaka kwa anthu omwe amamwa mankhwalawa tsiku lililonse. Kuti muchepetse zotsatirazi, choyenera ndikumwa mankhwalawo mukatha kudya ndipo adokotala angatanthauzenso kumwa choteteza m'mimba, tsiku lililonse, m'mimba yopanda kanthu, kuti muchepetse kusapeza bwino.
2. Colchicine
Colchicine ndi mankhwala omwe amagwiritsidwa ntchito kwambiri pochiza ndi kupewa kuukira kwa gout, chifukwa amachepetsa kuyikika kwa timibulu ta urate ndi zotsatira zake zotupa, motero kumachepetsa kupweteka. Mankhwalawa amatha kugwiritsidwa ntchito tsiku ndi tsiku popewa ziwopsezo, ndipo mlingowo ukhoza kuwonjezeka pakamachitika koopsa. Dziwani zambiri za mankhwalawa.
Zotsatira zoyipa kwambiri zomwe zimatha kuchitika ndikugwiritsa ntchito colchicine ndizovuta zam'mimba, monga kutsegula m'mimba, mseru ndi kusanza.
3. Ma Corticoids
Adotolo amalimbikitsa ma corticosteroids monga prednisolone m'mapiritsi kapena ma jakisoni, kuti muchepetse kupweteka ndi kutupa, komwe kumagwiritsidwa ntchito nthawi zambiri pomwe anthu sangatenge mankhwala ena opatsirana ndi kutupa monga indomethacin kapena celecoxib, mwachitsanzo, kapena sangathe kugwiritsa ntchito colchicine.
Zotsatira zoyipa kwambiri zomwe zimatha chifukwa chogwiritsa ntchito prednisolone ndikusintha kwamaganizidwe, kuchuluka kwa shuga m'magazi komanso kuthamanga kwa magazi. Dziwani kuti zovuta zina zimatha kuyambitsidwa ndi corticosteroids.
4. Zoletsa kupanga uric acid
Mankhwala omwe amagwiritsidwa ntchito kwambiri poletsa kupanga uric acid ndi allopurinol (Zyloric), yomwe imaletsa xanthine oxidase, yomwe ndi enzyme yomwe imasintha xanthine kukhala uric acid, yomwe imachepetsa milingo yake m'magazi, zomwe zimachepetsa chiopsezo cha kuoneka kwa zovuta. Onani zambiri zamankhwalawa.
Zotsatira zoyipa zomwe zimayambitsidwa ndi allopurinol ndi zotupa pakhungu.
5. Zithandizo zomwe zimawonjezera kuthetsedwa kwa uric acid
Mankhwala omwe angagwiritsidwe ntchito kuthetsa uric acid mu mkodzo ndi probenecid, zomwe zimapangitsa kuchepa kwa magazi. Dziwani zambiri za mankhwalawa.
Zotsatira zoyipa kwambiri zomwe zingachitike ndikugwiritsa ntchito mankhwalawa ndi zotupa pakhungu, kupweteka m'mimba ndi miyala ya impso.
Kuphatikiza apo, mankhwala ena, monga losartan, calcium channel antagonists, fenofibrate ndi statins, nawonso amathandizira kuchepetsa uric acid, chifukwa chake, pakafunika kulungamitsidwa, ayenera kuganiziridwa, poganizira phindu lawo mu gout.